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ellipticine

Known as: 5,11-dimethyl-6H-pyrido(4,3-b)carbazole 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (3)

Antineoplastic AgentsEllipticinesUncoupling Agents

Narrower (3)

NSC 71795ellipticine hydrochlorideellipticine tartrate

Papers overview

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Highly Cited
2008
Highly Cited
2008
Sequence Effect of Self-Assembling Peptides on the Complexation and In Vitro Delivery of the Hydrophobic Anticancer Drug Ellipticine
A special class of self-assembling peptides has been found to be capable of stabilizing the hydrophobic anticancer agent… 
2008
2008
A high-content chemical screen identifies ellipticine as a modulator of p53 nuclear localization
Abstractp53 regulates apoptosis and the cell cycle through actions in the nucleus and cytoplasm. Altering the subcellular… 
Highly Cited
2000
Highly Cited
2000
Synthesis of 6H-indolo[2,3-b][1,6]naphthyridines and related compounds as the 5-Aza analogues of ellipticine alkaloids.
Treatment of 2-(1-alkynyl)phenyl isocyanates 6 with the iminophosphorane 14 produced in situ the benzoenynyl carbodiimides 15… 
1992
1992
Molecular analysis of mutations induced by the intercalating agent ellipticine at the hisd3052 allele of salmonella typhimurium TA98
We have used DNA colony hybridization, the polymerase chain reaction (PCR), and direct DNA sequencing to determine the mutations… 
Highly Cited
1991
Highly Cited
1991
Sequence requirements for mammalian topoisomerase II mediated DNA cleavage stimulated by an ellipticine derivative.
Various antitumor drugs stabilize DNA topoisomerase II-DNA transient covalent complexes. The complexes distribution along pBR322… 
1982
1982
Metabolic activation of 2-amino-9H-pyrido[2,3-b]indole by rat-liver microsomes.
1982
1982
Uracil-DNA glycosylase. Purification and properties of uracil-DNA glycosylase from Micrococcus luteus.
1982
1982
Omega-hydroxylation of acyclic monoterpene alcohols by rat lung microsomes.
Highly Cited
1979
Highly Cited
1979
Relationship between cytotoxicity and DNA strand breakage produced by adriamycin and other intercalating agents.
Highly Cited
1971
Highly Cited
1971
Inhibition of the processing of ribosomal precursor RNA by intercalating agents.
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