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Ellipticines
Known as:
Ellipticines [Chemical/Ingredient]
Pyrido-CARBAZOLES originally discovered in the bark of OCHROSIA ELLIPTICA. They inhibit DNA and RNA synthesis and have immunosuppressive properties.
National Institutes of Health
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Related topics
Related topics
33 relations
Narrower (23)
12-hydroxyellipticine
13-hydroxyellipticine
13-oxoellipticine
2-methylellipticinium
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Broader (2)
Antineoplastic Agents, Phytogenic
Immunosuppressive Agents
In Blood
Process of secretion
agonists
antagonists & inhibitors
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2001
2001
Screening for and identification of novel agents directed at renal cell carcinoma.
S. Mertins
,
Timothy G Myers
,
+9 authors
Urologic Oncology Branch
Clinical Cancer Research
2001
Corpus ID: 30200211
We were interested in identifying novel agents for renal cell carcinoma (RCC) by screening for activities that model renal tumor…
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1997
1997
Structure-activity relationship for DNA topoisomerase II-induced DNA cleavage by azatoxin analogues.
J. Madalengoitia
,
J. Tepe
,
K. Werbovetz
,
E. Lehnert
,
T. Macdonald
Bioorganic & Medicinal Chemistry
1997
Corpus ID: 38803587
Review
1994
Review
1994
Clinical development of topoisomerase-interactive drugs.
F. Muggia
,
H. Burris
Advances in Pharmacology
1994
Corpus ID: 32774535
1994
1994
Cellular uptake as a determinant of cytotoxicity of quaternized ellipticines to human brain tumor cells.
D. Vistica
,
Susan Kenney
,
M. Hursey
,
Michael R. Boyd
Biochemical and Biophysical Research…
1994
Corpus ID: 8934407
The quaternized ellipticine derivative, 9-methoxy-N2-methylellipticinium acetate (MMEA), is representative of a group of…
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1994
1994
Design, synthesis, and study of 9-substituted ellipticine and 2-methylellipticinium analogues as potential CNS-selective antitumor agents.
W. Anderson
,
A. Gopalsamy
,
P. S. Reddy
Journal of Medicinal Chemistry
1994
Corpus ID: 28617818
N,N-Dimethylformamide (DMF) dineopentyl acetal-mediated O-alkylations of 9-hydroxyellipticine gave 9-ethoxy-, 9-(1-methylethoxy…
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1988
1988
A comparative model membrane study on structural effects of membrane-active positively charged anti-tumor drugs.
Klaas Nicolay
,
A. Sautereau
,
+4 authors
B. de Kruijff
Biochimica et Biophysica Acta
1988
Corpus ID: 39569953
1988
1988
Binding characteristics of 4-S proteins from rat and mouse liver. High affinity of ellipticines.
M. Roy
,
N. Fernandez
,
P. Lesca
European Journal of Biochemistry
1988
Corpus ID: 43252700
The binding characteristics of 4-S components (carcinogen-binding protein) from livers of Sprague-Dawley rats, C57BL/6 and DBA/2…
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Highly Cited
1980
Highly Cited
1980
DNA intercalating compounds as potential antitumor agents. 1. Preparation and properties of 7H-pyridocarbazoles.
D. Pélaprat
,
R. Oberlin
,
I. Le Guen
,
B. Roques
,
J. Le Pecq
Journal of Medicinal Chemistry
1980
Corpus ID: 24783365
The DNA intercalating compounds derived from 6H-pyridocarbazole (ellipticines, olivacines) elicit high antitumor properties. In…
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Highly Cited
1979
Highly Cited
1979
A class of strong inhibitors of microsomal monooxygenases: the ellipticines.
P. Lesca
,
E. Rafidinarivo
,
P. Lecointe
,
D. Mansuy
Chemico-Biological Interactions
1979
Corpus ID: 11608314
1977
1977
A new approach to the synthesis of ellipticines.
A. Jackson
,
P. R. Jenkins
,
P. Shannon
Journal of The Chemical Society-perkin…
1977
Corpus ID: 12176548
1,4-Dimethylcarbazole-3-carbaldehyde (2a) was condensed with aminoacetaldehyde diethyl acetal, and the Schiff's base was…
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