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Ellipticines

Known as: Ellipticines [Chemical/Ingredient] 
Pyrido-CARBAZOLES originally discovered in the bark of OCHROSIA ELLIPTICA. They inhibit DNA and RNA synthesis and have immunosuppressive properties.
National Institutes of Health

Related topics

Related topics

33 relations

Narrower (23)

12-hydroxyellipticine13-hydroxyellipticine13-oxoellipticine2-methylellipticinium

Broader (2)

Antineoplastic Agents, PhytogenicImmunosuppressive Agents
In BloodProcess of secretionagonistsantagonists & inhibitors

Papers overview

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Review
1994
Review
1994
DNA topoisomerase inhibitors.
1987
1987
Etude par radiolyse pulsée et gamma de la chimie radicalaire de certains composés antitumoraux appartenant à la famille des ellipticines : Influence de l'oxygène
Certains derives de l'ellipticine sont bien connus pour leurs proprietes cytotoxiques et antitumorales. L'hypothese d'une… 
1985
1985
Ellipticines: correlation between in vitro DNA intercalation and physiological properties?
The in vitro DNA-intercalator ellipticine and five of its derivatives have been investigated for some of their physiological… 
1984
1984
Synthèse de 5H-pyrido [3',4':4,5] pyrrolo [2,3-g] isoquinoléines disubstituées en 1,10 (aza-9 ellipticines)
Synthese des derives du titre disubtitues en 1,10 par diethylamino-3' propylamino ou diethylamino-3' hydroxy-2' propylamino a… 
1984
1984
Le BD-40, intercalant dérivé des aza-9 ellipticines, induit dans l'ADN cellulaire des cassures associées à des pontages protéiques.
: The nature of the lesions induced in cell DNA by BD-40, a chemical analog of Ellipticine was analyzed by submitting DNA from… 
1983
1983
Likelihood of the new antitumoral drug 10-[gamma-diethylaminopropylamino]-6-methyl-5H-pyrido[3',4':4,5]pyrrolo [2,3-g]isoquinoline (BD-40), a pyridopyrroloisoquinoline derivative, to induce DNA…
BD-40, a pyridopyrroloisoquinoline analogue of ellipticines, has dose-dependent cytostatic and cytotoxic effects on cultures of… 
1982
1982
[Syntheses designed to produce 8-amino ellipticine. Synthesis and pharmacological properties of 8-nitro ellipticine].
The synthesis of 8-nitro ellipticine starting from 6-nitro indole is reported. It is the first derivative of ellipticine… 
1980
1980
Interactions between ellipticine and phospholipids. Effect of ellipticine and 9-methoxyellipticine on the phase behaviour of phosphatidylglycerols. A monolayer study.
Ellipticine and some of its derivatives constitute an interesting class of substances displaying an antitumoral activity against… 
1980
1980
Antitumoral activity of dipyrido [4,3-b] [3,4-f] indoles on L 1210 leukemia.
Newly synthesized dipyrido [4,3-b] [3,4-f] indole compounds have a structural similarity with the DNA intercalating agents… 
1980
1980
Nitro-9 et amino-9 ellipticines et dérivés: synthèse et propriétés pharmacologiques.