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ebselen
Known as:
2-phenyl-1,2-benzoisoselenazol-3(2H)-one
A organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity. Ebselen acts as a glutathione peroxidase mimetic and is…
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National Institutes of Health
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Related topics
Related topics
9 relations
Broader (7)
Anti-Inflammatory Agents, Non-Steroidal
Anti-Ulcer Agent
Antioxidants
Azoles
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Narrower (2)
DR 3305
PZ 51
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Speaker 4: Kim Do,Switzerland
D. Dwir
,
J. Cabungcal
,
P. Steullet
,
M. Cuenod
,
K. Do
International Journal of Neuropsychopharmacology
2016
Corpus ID: 45500012
2008
2008
Study of biomarkers to evaluate the protective effects of antioxidants against manganese neurotoxicity
M. L. Santos
2008
Corpus ID: 56329511
Tese de mestrado, Biologia (Biologia Humana e Ambiente), 2008, Universidade de Lisboa, Faculdade de Ciencias
2008
2008
The Protective Role of Ebselen and VitE on Hypertensive Heart Damage in NO-deficient Rats
Si Zhou
2008
Corpus ID: 76178684
Background Chronic administration with inhibitor of nitric oxide synthase (N_ω-nitro-L-arginine methyl ester,L-NAME) induces…
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2005
2005
Selective inhibition of leukotriene B4 formation by Ebselen: A novel approach to antiinflammatory therapy
P. Kuhl
,
Harald Borbe
,
A. Römer
,
H. Fischer
,
M. J. Parnham
Agents and Actions
2005
Corpus ID: 40046579
Leukotriene B4 (LTB4) is a dihydroxy metabolite of arachidonic acid, released by stimulated leukocytes, and a potent stimulator…
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2005
2005
Preparation and dissolution of Ebselen solid dispersion
Mei Zhang
2005
Corpus ID: 102419970
OBJECTIVE To improve the dissolution of ebselen in vitro.METHODS Ebselen solid dispersion was prepared. The dissolutions of the…
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Review
2003
Review
2003
Organoselenium Compounds as Glutathione Peroxidase Mimics
Carolyn J. Fisher
2003
Corpus ID: 53476263
Glutathione peroxidase (GPx) is a selenoenzyme that protects biological membranes and other cellular components from oxidative…
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Review
2001
Review
2001
[Neuroprotective therapy for the treatment of acute ischemic stroke].
H. Naritomi
Rinshō shinkeigaku Clinical neurology
2001
Corpus ID: 31017697
Following cerebral ischemia, various biochemical reactions are provoked in a stepwise manner leading neuronal cells to ischemic…
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1996
1996
The Synthesis and Anti-lipid Peroxidation Activity of Amino Acid Derivatives of Ebselen
Xiao Ying
1996
Corpus ID: 88344703
Amino acid was used as a carrier of the active molecule──ebselen,which mimicked the properties of GSH-Px and was known as an anti…
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1993
1993
Synthesis and Anti-tumor Activity of Ebselen and Its Derivatives
Zhi Zhou
1993
Corpus ID: 101986567
Ebselen is a organoselenium compound. It exhibits anti-tumor oxidant activity similar to that of glutathione-peroxidase(GSH-Px…
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1989
1989
Effect of Ebselen (PZ-51) in Liver Failure Induced by Propionibacterium acnes (P. acnes)
M. Akasaki
,
T. Ikeda
,
F. Numata
,
Y. Kurebayashi
,
W. Tsukada
1989
Corpus ID: 68226180
Intravenous injection of P. acnes and lipopolysaccharide (LPS) into BALB/c mice resulted in acute liver failure. Treatment with…
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