ebselen

Known as: 2-phenyl-1,2-benzoisoselenazol-3(2H)-one 
A organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity. Ebselen acts as a glutathione peroxidase mimetic and is… (More)
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
Although the accelerated atherosclerosis and premature aging of the cardiovascular system in patients with metabolic syndrome… (More)
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Highly Cited
2004
Highly Cited
2004
Zucker diabetic fat (ZDF) rats with the metabolic syndrome and hyperlipidemia develop focal and segmental sclerosis. The role of… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Altered endothelial cell nitric oxide (NO(*)) production in atherosclerosis may be due to a reduction of intracellular… (More)
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Highly Cited
2000
Highly Cited
2000
Doxorubicin (DOX) is a broad spectrum anthracycline antibiotic used to treat a variety of cancers. Redox activation of DOX to… (More)
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Review
2000
Review
2000
Stroke occurs due to haemorrhage or occlusive injury and results in ischaemia and reperfusion injury. A variety of destructive… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND AND PURPOSE The effect of ebselen, a seleno-organic compound with antioxidant activity through a glutathione… (More)
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Highly Cited
1998
Highly Cited
1998
Transcriptional activation of erythropoietin, glycolytic enzymes, and vascular endothelial growth factor occurs during hypoxia or… (More)
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Highly Cited
1998
Highly Cited
1998
Background and Purpose—The effect of ebselen, a seleno-organic compound with antioxidant activity through a glutathione… (More)
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1996
1996
Ebselen, 2-phenyl-1,2-benzisoselenazol-3(2H)-one, rapidly reacts with peroxynitrite, the rate constant being of the order of 10(6… (More)
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Review
1995
Review
1995
1. Ebselen (2-phenyl-1,2-benzisoselenazol-3(2H)-one) is a non-toxic seleno-organic drug with antiinflammatory… (More)
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