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Azole resistance in Aspergillus fumigatus has now been reported from 6 continents and is emerging as a global health problem. The… Expand Once considered the 'holy grail' of organometallic chemistry, synthetically useful reactions employing C-H bond activation have… Expand
An increase in the frequency of azole-resistant Aspergillus fumigatus has emerged.
Background Resistance to triazoles was recently reported in Aspergillus fumigatus isolates cultured from patients with invasive… Expand Huisgen's 1,3-dipolar cycloadditions become nonconcerted when copper(I) acetylides react with azides and nitrile oxides… Expand SUMMARY Candida albicans is the most common fungal pathogen of humans and has developed an extensive repertoire of putative… Expand SUMMARY Major developments in research into the azole class of antifungal agents during the 1990s have provided expanded options… Expand Resistance to azole antifungal agents in Candida albicans can be mediated by multidrug efflux transporters. In a previous study… Expand Azole antifungal agents, and especially fluconazole, have been used widely to treat oropharyngeal candidiasis in patients with… Expand