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Chlormethiazole
Known as:
CLOMETHIAZOLE
, Chlormethiazole [Chemical/Ingredient]
, Thiazole, 5-(2-chloroethyl)-4-methyl-
A sedative and anticonvulsant often used in the treatment of alcohol withdrawal. Chlormethiazole has also been proposed as a neuroprotective agent…
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National Institutes of Health
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Related topics
Related topics
15 relations
Narrower (3)
5-acetyl-4-methylthiazole
Distraneurin
clomethiazole edisylate
Broader (5)
Anticonvulsants
Azoles
GABA Modulators
Hypnotics and Sedatives
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In Blood
agonists
analogs & derivatives
antagonists & inhibitors
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2002
2002
Preconditioned resistance to oxygen–glucose deprivation-induced cortical neuronal death: alterations in vesicular GABA and glutamate release
M. Grabb
,
D. Lobner
,
D. Turetsky
,
D. Choi
Neuroscience
2002
Corpus ID: 22840208
2002
2002
Clinical trial of the neuroprotectant clomethiazole in coronary artery bypass graft surgery: a randomized controlled trial.
R. Kong
,
J. Butterworth
,
+6 authors
S. Newman
Anesthesiology
2002
Corpus ID: 41919059
BACKGROUND The neuroprotective property of clomethiazole has been demonstrated in several animal models of global and focal brain…
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2000
2000
On the regulation of ischaemia‐induced glutamate efflux from rat cortex by GABA; in vitro studies with GABA, clomethiazole and pentobarbitone
R. M. Nelson
,
A. Green
,
D. Lambert
,
A. H. Hainsworth
British Journal of Pharmacology
2000
Corpus ID: 37384018
Prisms of adult rat cortex were maintained in vitro in either aerobic conditions (control) or conditions simulating an acute…
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Highly Cited
1999
Highly Cited
1999
Cubic phases for studies of drug partition into lipid bilayers.
Sven Engström
,
Tomas Petersson Nordén
,
Håkan Nyquist
European Journal of Pharmaceutical Sciences
1999
Corpus ID: 6384707
Highly Cited
1995
Highly Cited
1995
The effect of chlormethiazole on neuronal damage in a model of transient focal ischaemia
S. Sydserff
,
A. Cross
,
K. J. West
,
A. Green
British Journal of Pharmacology
1995
Corpus ID: 13325885
1 The effect of chlormethiazole has been studied in a transient middle cerebral artery (MCA) occlusion model of cerebral…
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Highly Cited
1995
Highly Cited
1995
The protective action of chlormethiazole against ischaemia‐induced neurodegeneration in gerbils when infused at doses having little sedative or anticonvulsant activity
A. Cross
,
J. A. Jones
,
M. Snares
,
K. Jostell
,
U. Bredberg
,
A. Green
British Journal of Pharmacology
1995
Corpus ID: 37095952
1 The effect of chlormethiazole administration on delayed neuronal death in gerbil hippocampus following transient global…
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1987
1987
Harman induces preference for ethanol in rats: Is the effect specific for ethanol?
H. Rommelspacher
,
Cornelia Büchau
,
J. Weiss
Pharmacology, Biochemistry and Behavior
1987
Corpus ID: 29653675
Highly Cited
1982
Highly Cited
1982
Interactions between drugs and intravenous delivery systems.
E. Kowaluk
,
M. Roberts
,
A. Polack
American journal of hospital pharmacy
1982
Corpus ID: 41929802
The loss of 45 drugs from intravenous solutions during simulated infusions through plastic infusion sets; factors affecting such…
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1981
1981
Anticonvulsant Therapy. Pharmacological Basis and Practice. Second edition
Mervin J. Eadie
,
J. Tyrer
,
Henn Kutt
1981
Corpus ID: 72017998
Highly Cited
1980
Highly Cited
1980
Improved hypnotic treatment using chlormethiazole and temazepam.
R. Briggs
,
C. Castleden
,
C. Kraft
British medical journal
1980
Corpus ID: 21998568
The effects of a single 384 mg oral dose of chlormethiazole were compared with those of 20 mg of temazepam and placebo in healthy…
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