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Chlormethiazole
Known as:
CLOMETHIAZOLE
, Chlormethiazole [Chemical/Ingredient]
, Thiazole, 5-(2-chloroethyl)-4-methyl-
A sedative and anticonvulsant often used in the treatment of alcohol withdrawal. Chlormethiazole has also been proposed as a neuroprotective agent…
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National Institutes of Health
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Related topics
Related topics
15 relations
Narrower (3)
5-acetyl-4-methylthiazole
Distraneurin
clomethiazole edisylate
Broader (5)
Anticonvulsants
Azoles
GABA Modulators
Hypnotics and Sedatives
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In Blood
agonists
analogs & derivatives
antagonists & inhibitors
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
CYP2E1 potentiates binge alcohol-induced gut leakiness, steatohepatitis, and apoptosis.
M. Abdelmegeed
,
A. Banerjee
,
+5 authors
B. Song
Free Radical Biology & Medicine
2013
Corpus ID: 13796138
Highly Cited
2008
Highly Cited
2008
Cytochrome P450 2E1 contributes to ethanol‐induced fatty liver in mice
Yongke Lu
,
J. Zhuge
,
Xiaodong Wang
,
J. Bai
,
A. Cederbaum
Hepatology
2008
Corpus ID: 205864994
Cytochrome P450 2E1 (CYP2E1) is suggested to play a role in alcoholic liver disease, which includes alcoholic fatty liver…
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Highly Cited
2007
Highly Cited
2007
A simple and reliable procedure for the determination of psychoactive drugs in oral fluid by gas chromatography-mass spectrometry.
M. Pujadas
,
S. Pichini
,
E. Civit
,
E. Santamariña
,
Katherine Pérez
,
R. de la Torre
Journal of Pharmaceutical and Biomedical Analysis
2007
Corpus ID: 2574692
Highly Cited
2002
Highly Cited
2002
Clomethiazole Acute Stroke Study in Ischemic Stroke (CLASS-I): Final Results
P. Lyden
,
A. Shuaib
,
+8 authors
E. Salazar-Grueso
Stroke
2002
Corpus ID: 1012405
Background and Purpose— A previous trial (the Clomethiazole Acute Stroke Study) generated the hypothesis that clomethiazole is…
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Highly Cited
2001
Highly Cited
2001
A study of the mechanisms involved in the neurotoxic action of 3,4‐methylenedioxymethamphetamine (MDMA, ‘ecstasy’) on dopamine neurones in mouse brain
M. Colado
,
J. Camarero
,
+4 authors
A. Green
British Journal of Pharmacology
2001
Corpus ID: 20672348
Administration of 3,4‐methylenedioxymethamphetamine (MDMA, ‘ecstasy’) to mice produces acute hyperthermia and long‐term…
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Review
2000
Review
2000
GABA potentiation: a logical pharmacological approach for the treatment of acute ischaemic stroke
A. Green
,
A. Hainsworth
,
D. Jackson
Neuropharmacology
2000
Corpus ID: 39073036
Highly Cited
2000
Highly Cited
2000
Use of headspace solid-phase microextraction (HS-SPME) in hair analysis for organic compounds.
F. Sporkert
,
F. Pragst
Forensic Science International
2000
Corpus ID: 25024612
Highly Cited
1999
Highly Cited
1999
Ethyl glucuronide--a marker of alcohol consumption and a relapse marker with clinical and forensic implications.
F. Wurst
,
C. Kempter
,
S. Seidl
,
A. Alt
Alcohol and Alcoholism
1999
Corpus ID: 15451836
Ethyl glucuronide (EtG) is a non-volatile, water-soluble, direct metabolite of ethanol that can be detected in body fluids and…
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Highly Cited
1999
Highly Cited
1999
Clomethiazole acute stroke study (CLASS): results of a randomized, controlled trial of clomethiazole versus placebo in 1360 acute stroke patients.
N. Wahlgren
,
K. Ranasinha
,
+4 authors
L. Claesson
Stroke
1999
Corpus ID: 133681
BACKGROUND AND PURPOSE The efficacy and safety of the neuroprotective drug clomethiazole was tested in a double blind placebo…
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Highly Cited
1997
Highly Cited
1997
A new rating scale for the assessment of the alcohol-withdrawal syndrome (AWS scale).
T. Wetterling
,
R. Kanitz
,
+5 authors
M. Driessen
Alcohol and Alcoholism
1997
Corpus ID: 2453190
A new rating scale for the quantitative assessment of the alcohol-withdrawal syndrome (AWS) was developed from the CIWA-A scale…
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