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Chlormethiazole

Known as: CLOMETHIAZOLE, Chlormethiazole [Chemical/Ingredient], Thiazole, 5-(2-chloroethyl)-4-methyl- 
A sedative and anticonvulsant often used in the treatment of alcohol withdrawal. Chlormethiazole has also been proposed as a neuroprotective agent… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2005
Review
2005
BackgroundThe recurrent failure of apparently promising neuroprotective drugs to improve outcome in trials of patients with acute… Expand
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Highly Cited
2002
Highly Cited
2002
Background and Purpose— A previous trial (the Clomethiazole Acute Stroke Study) generated the hypothesis that clomethiazole is… Expand
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Highly Cited
2001
Highly Cited
2001
Administration of 3,4‐methylenedioxymethamphetamine (MDMA, ‘ecstasy’) to mice produces acute hyperthermia and long‐term… Expand
Review
2000
Review
2000
It has been shown that enhancing the function of the major inhibitory neurotransmitter GABA decreases glutamatergic activity in… Expand
Highly Cited
2000
Highly Cited
2000
Headspace solid phase microextraction (HS-SPME) has advantages of high purity of the extract, avoidance of organic solvents and… Expand
Highly Cited
1999
Highly Cited
1999
Ethyl glucuronide (EtG) is a non-volatile, water-soluble, direct metabolite of ethanol that can be detected in body fluids and… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND AND PURPOSE The efficacy and safety of the neuroprotective drug clomethiazole was tested in a double blind placebo… Expand
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Highly Cited
1997
Highly Cited
1997
A new rating scale for the quantitative assessment of the alcohol-withdrawal syndrome (AWS) was developed from the CIWA-A scale… Expand
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Highly Cited
1991
Highly Cited
1991
1 The effect of chlormethiazole, and other drugs which potentiate γ‐aminobutyric acid (GABA) function on delayed neuronal death… Expand
Highly Cited
1986
Highly Cited
1986
Publisher Summary This chapter focuses on the effects of hypnotics and sedatives. Chlormethiazole is widely used as a hypnotic… Expand