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drug binding

Known as: binding drug, binding drugs 
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when… Expand
National Institutes of Health

Related topics

Related topics

4 relations
Blood Proteinsreceptor binding

Broader (2)

Drug Kineticsbiochemical mechanism

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Weak-binding molecules are not drugs?—toward a systematic strategy for finding effective weak-binding drugs
Designing maximally selective ligands that act on individual drug targets with high binding affinity has been the central dogma… Expand
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2016
2016
Neutron structure of human carbonic anhydrase II in complex with methazolamide: mapping the solvent and hydrogen-bonding patterns of an effective clinical drug
The room-temperature X-ray/neutron structure of human carbonic anhydrase II in complex with methazolamide has been determined… Expand
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2016
2016
2-(m-Azidobenzoyl)taxol binds differentially to distinct β-tubulin isotypes
Significance β-Tubulin is a validated target for Taxol. There are seven β-tubulin isotypes present in distinct quantities in… Expand
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2016
2016
Mutant bacterial sodium channels as models for local anesthetic block of eukaryotic proteins
ABSTRACT Voltage gated sodium channels are the target of a range of local anesthetic, anti-epileptic and anti-arrhythmic… Expand
2016
2016
Albumin-binding drugs as drug delivery systems in oncology
2015
2015
Fatty Acid Binding Proteins Expressed at the Human Blood–Brain Barrier Bind Drugs in an Isoform-Specific Manner
ABSTRACTPurposeTo examine the expression of fatty acid binding proteins (FABPs) at the human blood–brain barrier (BBB) and to… Expand
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Review
2014
Review
2014
Complex Interplay between the P-Glycoprotein Multidrug Efflux Pump and the Membrane: Its Role in Modulating Protein Function
  • F. Sharom
  • Front. Oncol.
  • 2014
    • Corpus ID: 11609355
Multidrug resistance in cancer is linked to expression of the P-glycoprotein multidrug transporter (Pgp, ABCB1), which exports… Expand
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2014
2014
Calorimetric investigation of diclofenac drug binding to a panel of moderately glycated serum albumins.
Glycation alters the drug binding properties of serum proteins and could affect free drug concentrations in diabetic patients… Expand
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Review
2008
Review
2008
Designing transient binding drugs: a new concept for drug discovery.
  • S. Ohlson
  • Drug discovery today
  • 2008
    • Corpus ID: 207151341
A multitude of weak, or transient, biological interactions (dissociation constant: K(d)>microM), either working alone or in… Expand
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Review
1999
Review
1999
Structure-based and combinatorial search for new RNA-binding drugs.
The discovery by structure-based and combinatorial methods of new RNA-binding drugs presents great opportunities for… Expand
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