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Drug Kinetics

Known as: PK, Pharmacokinetics, Kinetics, Drug 
Dynamic and kinetic mechanisms of exogenous chemical and DRUG LIBERATION; ABSORPTION; BIOLOGICAL TRANSPORT; TISSUE DISTRIBUTION; BIOTRANSFORMATION… 
National Institutes of Health

Related topics

Related topics

20 relations
Biological AvailabilityBody partBody spaceBody tissue

Narrower (6)

Drug effect disorderMetabolic Clearance Ratedrug absorptiondrug binding

Broader (3)

PharmacologyUptakepharmacology and toxicology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Strain specificity in antimicrobial activity of silver and copper nanoparticles.
Review
2008
Review
2008
Pharmacokinetics and biodistribution of nanoparticles.
Nanoparticles show their promise for improving the efficacy of drugs with a narrow therapeutic window or low bioavailability… 
Highly Cited
2007
Highly Cited
2007
Half-Life of Serum Elimination of Perfluorooctanesulfonate,Perfluorohexanesulfonate, and Perfluorooctanoate in Retired Fluorochemical Production Workers
Background The presence of perfluorooctanesulfonate (PFOS), perfluorohexanesulfonate (PFHS), and perfluorooctanoate (PFOA) has… 
Review
2002
Review
2002
Nonsteroidal anti-inflammatory drugs as anticancer agents: mechanistic, pharmacologic, and clinical issues.
Numerous experimental, epidemiologic, and clinical studies suggest that nonsteroidal anti-inflammatory drugs (NSAIDs… 
Review
2001
Review
2001
Oral anticoagulants: mechanism of action, clinical effectiveness, and optimal therapeutic range.
Abbreviations: AFASAK 5 Atrial Fibrillation, Aspirin, Anticoagulation; AMI 5 acute myocardial infarction; AF 5 atrial… 
Highly Cited
2000
Highly Cited
2000
Specificity and mechanism of action of some commonly used protein kinase inhibitors.
The specificities of 28 commercially available compounds reported to be relatively selective inhibitors of particular serine… 
Review
1994
Review
1994
Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications.
Review
1992
Review
1992
Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic and psychostimulant effects
Highly Cited
1990
Highly Cited
1990
Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.
Thapsigargin, a tumor-promoting sesquiterpene lactone, discharges intracellular Ca2+ in rat hepatocytes, as it does in many… 
Highly Cited
1971
Highly Cited
1971
Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs.
  • J. Vane
  • Nature: New biology
  • 1971
  • Corpus ID: 19514782
Experiments with guinea-pig lung suggest that some of the therapeutic effects of sodium salicylate and aspirin-like drugs are due… 
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