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Drug Kinetics
Known as:
PK
, Pharmacokinetics
, Kinetics, Drug
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Dynamic and kinetic mechanisms of exogenous chemical and DRUG LIBERATION; ABSORPTION; BIOLOGICAL TRANSPORT; TISSUE DISTRIBUTION; BIOTRANSFORMATION…
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National Institutes of Health
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Related topics
Related topics
20 relations
Biological Availability
Body part
Body space
Body tissue
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Narrower (6)
Drug effect disorder
Metabolic Clearance Rate
drug absorption
drug binding
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Broader (3)
Pharmacology
Uptake
pharmacology and toxicology
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Phase I trial of veliparib, (ABT-888), a poly(ADP-ribose) polymerase (PARP) inhibitor, in combination with doxorubicin and cyclophosphamide in breast cancer and other solid tumors.
Antoinette R. Tan
,
D. Toppmeyer
,
+9 authors
R. DiPaola
Journal of Clinical Oncology
2011
Corpus ID: 13552359
3041 Background: Veliparib is a potent, oral inhibitor of PARP-1 and PARP-2. We previously reported phase I results of veliparib…
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1999
1999
Establishing Data-Derived Adjustment Factors from Published Pharmaceutical Clinical Trial Data
K. Silverman
,
B. Naumann
,
+4 authors
M. Gallo
1999
Corpus ID: 73085026
In non-cancer risk assessment the goal traditionally has been to protect the majority of people by setting limits that account…
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1982
1982
A potential mechanism of action of colloidal bismuth subcitrate: diffusion barrier to hydrochloric acid.
Lee Sp
1982
Corpus ID: 58791335
: The mode of action of colloidal bismuth subcitrate (CBS), a colloidal bismuth preparation often used in the treatment of…
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Review
1980
Review
1980
Drug Kinetics in Childbirth
R. Nation
Clinical Pharmacokinetics
1980
Corpus ID: 27585288
SummaryDrugs from a wide range of pharmacological classes are commonly given to women in childbirth, either for a maternal effect…
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Highly Cited
1977
Highly Cited
1977
Drug Kinetics and Artificial Kidneys
T. Gibson
,
H. Nelson
Clinical Pharmacokinetics
1977
Corpus ID: 37536874
The factors affecting solute movement across the membrane during haemodialysis are well understood. Likewise the mathematics of…
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Highly Cited
1975
Highly Cited
1975
The immunological response of the rat to infection with Taenia taeniaeformis. V. Sequence of appearance of protective immunoglobulins and the mechanism of action of 7Sgamma2a antibodies.
A. Musoke
,
J. F. Williams
Immunology
1975
Corpus ID: 6991289
Passive transfer of immunity to Taenia taeniaeformis was achieved with serum taken 14, 21, 49 and 63 days after infection. The…
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Highly Cited
1970
Highly Cited
1970
Studies on the mechanism of action of diphenylhydantoin.
J. Pincus
,
I. Grove
,
B. Mariño
,
G. Glaser
Archives of Neurology
1970
Corpus ID: 30822251
IN EXPERIMENTS reported in 1955, Woodbury 1 demonstrated in normal rats that the intracellular concentration of brain sodium was…
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1967
1967
On the contractile response of the isolated rat uterus to prostaglandin E1.
D. Paton
,
E. Daniel
Canadian Journal of Physiology and Pharmacology
1967
Corpus ID: 34514843
The mechanism of action of prostaglandin E1 (PGE1) on rat uterine horns was analyzed. Contractile responses to PGE1 were not due…
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Review
1961
Review
1961
Treatment of hypercholesteremia by nicotinic acid. Progress report with review of studies regarding mechanism of action.
W. Parsons
Archives of Internal Medicine
1961
Corpus ID: 42462686
Introduction The use of nicotinic acid in large doses has gained wide recognition as a means of reducing serum cholesterol levels…
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Highly Cited
1957
Highly Cited
1957
A possible mechanism of action of quinidine.
W. Holland
American Journal of Physiology
1957
Corpus ID: 36028576
Quinidine increases the refractory period and depresses both the rate and amplitude of beat of isolated rabbit atria. These…
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