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Drug Kinetics

Known as: PK, Pharmacokinetics, Kinetics, Drug 
Dynamic and kinetic mechanisms of exogenous chemical and DRUG LIBERATION; ABSORPTION; BIOLOGICAL TRANSPORT; TISSUE DISTRIBUTION; BIOTRANSFORMATION… 
National Institutes of Health

Related topics

Related topics

20 relations
Biological AvailabilityBody partBody spaceBody tissue

Narrower (6)

Drug effect disorderMetabolic Clearance Ratedrug absorptiondrug binding

Broader (3)

PharmacologyUptakepharmacology and toxicology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Randomized, double-blind, double-dummy, vehicle-controlled study of ingenol mebutate gel 0.025% and 0.05% for actinic keratosis.
Highly Cited
2001
Highly Cited
2001
Anti-Fas-induced apoptosis in chondrocytes reduced by hyaluronan: evidence for CD44 and CD54 (intercellular adhesion molecule 1) invovement.
OBJECTIVE To investigate the in vitro effect of therapeutic hyaluronan (HA) of 500-730 kd on anti-Fas-induced apoptosis of… 
Highly Cited
2000
Highly Cited
2000
Effects of 4‐nonylphenol on fecundity and biomarkers of estrogenicity in fathead minnows (Pimephales promelas)
Aultfathead minnows (Pimophales promelas) were exposed to waterborne concentrations of 4‐nonylphenol (NP) ranging from 0.05 to 3… 
Highly Cited
1990
Highly Cited
1990
Mechanism of cardiac defibrillation in open-chest dogs with unipolar DC-coupled simultaneous activation and shock potential recordings.
The automatic implantable cardioverter-defibrillator has been shown to dramatically improve survival. The future refinement of… 
Review
1988
Review
1988
A Review of Organophosphate Poisoning
SummaryMany organophosphate compounds are pesticides widely used for the control of insect vectors. They are not ideal agents… 
Highly Cited
1987
Highly Cited
1987
Regulation of Eicosanoid Production: Role of Phospholipases and Inhibitors
The control of prostaglandin and leukotriene biosynthesis in inflammatory and other cells depends on the enzymatic release of… 
Highly Cited
1983
Highly Cited
1983
Activation of calcium channels by novel 1,4-dihydropyridines. A new mechanism for positive inotropics or smooth muscle stimulants.
The effects of the novel, 1,4-dihydropyridine derivative methyl 1,4-dihydro-2,6-dimethyl-3-nitro-4-(2-trifluoromethylphenyl… 
Review
1982
Review
1982
Angiotensin‐converting enzyme inhibitors: Medicinal chemistry and biological actions
A decade of experimentation, with work in the last four years greatly accelerated by the availability of captopril, favors the… 
Highly Cited
1981
Highly Cited
1981
Calcium: its role in the mechanism of action of angiotensin II and potassium in aldosterone production.
The role of calcium in the angiotensin II- or potassium-mediated increase in aldosterone production was analyzed in isolated… 
Review
1972
Review
1972
Studies on the mechanism of action of local anesthetics with phospholipid model membranes.
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