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Drug Kinetics
Known as:
PK
, Pharmacokinetics
, Kinetics, Drug
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Dynamic and kinetic mechanisms of exogenous chemical and DRUG LIBERATION; ABSORPTION; BIOLOGICAL TRANSPORT; TISSUE DISTRIBUTION; BIOTRANSFORMATION…
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National Institutes of Health
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Related topics
Related topics
20 relations
Biological Availability
Body part
Body space
Body tissue
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Narrower (6)
Drug effect disorder
Metabolic Clearance Rate
drug absorption
drug binding
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Broader (3)
Pharmacology
Uptake
pharmacology and toxicology
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Phase I trial of veliparib, (ABT-888), a poly(ADP-ribose) polymerase (PARP) inhibitor, in combination with doxorubicin and cyclophosphamide in breast cancer and other solid tumors.
Antoinette R. Tan
,
D. Toppmeyer
,
+9 authors
R. DiPaola
Journal of Clinical Oncology
2011
Corpus ID: 13552359
3041 Background: Veliparib is a potent, oral inhibitor of PARP-1 and PARP-2. We previously reported phase I results of veliparib…
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Review
1996
Review
1996
[Antiepileptic drugs: mechanism of action].
J. M. Mercadé Cerdá
Neurología
1996
Corpus ID: 68208430
Great progress has been made in the development of antiepileptic drugs (AEDs) from their early empirical stage until the current…
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1995
1995
Continuous infusion of ceftazidime in febrile neutropenic patients with acute myeloid leukemia
S. Daenen
,
Z. Erjavec
,
D. Uges
,
H. Vries-Hospers
,
P. Jonge
,
M. Halie
European Journal of Clinical Microbiology and…
1995
Corpus ID: 42035793
Twelve febrile patients with severe neutropenia, who had undergone aggressive chemotherapy for acute myeloid leukemia, were…
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1982
1982
A potential mechanism of action of colloidal bismuth subcitrate: diffusion barrier to hydrochloric acid.
Lee Sp
1982
Corpus ID: 58791335
: The mode of action of colloidal bismuth subcitrate (CBS), a colloidal bismuth preparation often used in the treatment of…
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Review
1980
Review
1980
Drug Kinetics in Childbirth
R. Nation
Clinical Pharmacokinetics
1980
Corpus ID: 27585288
SummaryDrugs from a wide range of pharmacological classes are commonly given to women in childbirth, either for a maternal effect…
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Highly Cited
1977
Highly Cited
1977
Drug Kinetics and Artificial Kidneys
T. Gibson
,
Howard A. Nelson
Clinical Pharmacokinetics
1977
Corpus ID: 37536874
The factors affecting solute movement across the membrane during haemodialysis are well understood. Likewise the mathematics of…
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Review
1977
Review
1977
Influence of Sex on Drug Kinetics in Man
J. Giudicelli
,
J. Tillement
Clinical Pharmacokinetics
1977
Corpus ID: 25090219
SummaryVery few investigations in man have been specifically devoted to the influence of sex on drug kinetics. Although the…
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Highly Cited
1975
Highly Cited
1975
The immunological response of the rat to infection with Taenia taeniaeformis. V. Sequence of appearance of protective immunoglobulins and the mechanism of action of 7Sgamma2a antibodies.
A. Musoke
,
J. F. Williams
Immunology
1975
Corpus ID: 6991289
Passive transfer of immunity to Taenia taeniaeformis was achieved with serum taken 14, 21, 49 and 63 days after infection. The…
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Highly Cited
1957
Highly Cited
1957
A possible mechanism of action of quinidine.
W. Holland
American Journal of Physiology
1957
Corpus ID: 36028576
Quinidine increases the refractory period and depresses both the rate and amplitude of beat of isolated rabbit atria. These…
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1954
1954
The distribution of radioactivity following administration of triethylenimino-s-triazine-C14 in tumor-bearing and control mice.
M. V. Nadkarni
,
Edwin I. Goldenthal
,
Paul K. Smith
Cancer Research
1954
Corpus ID: 16095581
1. Triethylenimino-1-3-5-triazine-C14 was synthesized from urea-C14. 2. A study was made of the excretion and tissue…
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