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Drug Kinetics

Known as: PK, Pharmacokinetics, Kinetics, Drug 
Dynamic and kinetic mechanisms of exogenous chemical and DRUG LIBERATION; ABSORPTION; BIOLOGICAL TRANSPORT; TISSUE DISTRIBUTION; BIOTRANSFORMATION… 
National Institutes of Health

Related topics

Related topics

20 relations
Biological AvailabilityBody partBody spaceBody tissue

Narrower (6)

Drug effect disorderMetabolic Clearance Ratedrug absorptiondrug binding

Broader (3)

PharmacologyUptakepharmacology and toxicology

Papers overview

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2011
2011
Phase I trial of veliparib, (ABT-888), a poly(ADP-ribose) polymerase (PARP) inhibitor, in combination with doxorubicin and cyclophosphamide in breast cancer and other solid tumors.
3041 Background: Veliparib is a potent, oral inhibitor of PARP-1 and PARP-2. We previously reported phase I results of veliparib… 
1988
1988
Effect of several penetration enhancers on the percutaneous absorption of indomethacin in hairless rats.
In order to measure the effect of several penetration enhancers on the percutaneous absorption of drugs and to classify the… 
1982
1982
A potential mechanism of action of colloidal bismuth subcitrate: diffusion barrier to hydrochloric acid.
: The mode of action of colloidal bismuth subcitrate (CBS), a colloidal bismuth preparation often used in the treatment of… 
Review
1980
Review
1980
Drug Kinetics in Childbirth
SummaryDrugs from a wide range of pharmacological classes are commonly given to women in childbirth, either for a maternal effect… 
Highly Cited
1977
Highly Cited
1977
Drug Kinetics and Artificial Kidneys
The factors affecting solute movement across the membrane during haemodialysis are well understood. Likewise the mathematics of… 
Review
1977
Review
1977
Influence of Sex on Drug Kinetics in Man
SummaryVery few investigations in man have been specifically devoted to the influence of sex on drug kinetics. Although the… 
Highly Cited
1975
Highly Cited
1975
The immunological response of the rat to infection with Taenia taeniaeformis. V. Sequence of appearance of protective immunoglobulins and the mechanism of action of 7Sgamma2a antibodies.
Passive transfer of immunity to Taenia taeniaeformis was achieved with serum taken 14, 21, 49 and 63 days after infection. The… 
1967
1967
On the contractile response of the isolated rat uterus to prostaglandin E1.
The mechanism of action of prostaglandin E1 (PGE1) on rat uterine horns was analyzed. Contractile responses to PGE1 were not due… 
Highly Cited
1957
Highly Cited
1957
A possible mechanism of action of quinidine.
Quinidine increases the refractory period and depresses both the rate and amplitude of beat of isolated rabbit atria. These… 
1954
1954
The distribution of radioactivity following administration of triethylenimino-s-triazine-C14 in tumor-bearing and control mice.
1. Triethylenimino-1-3-5-triazine-C14 was synthesized from urea-C14. 2. A study was made of the excretion and tissue…