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Molecular origin of cancer: catechol estrogen-3,4-quinones as endogenous tumor initiators.
TLDR
The hypothesis that CE-3,4-Q are endogenous tumor initiators is supported, supported by data that indicates that depurinating hydrocarbon-DNA adducts generate oncogenic mutations found in mouse skin papillomas.
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Phycobilisomes Supply Excitations to Both Photosystems in a Megacomplex in Cyanobacteria
TLDR
In vivo protein cross-linking, mass spectrometry, and time-resolved spectroscopy indicates that the megacomplex is organized to facilitate energy transfer but not intercomplex electron transfer, which requires diffusible intermediates and the cytochrome b6f complex.
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MRI Is a DNA Damage Response Adaptor during Classical Non-homologous End Joining.
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Fourier transform mass spectrometry.
Fourier transform mass spectrometry will play an important role in the future because of its unique combination of high mass resolution, high upper mass limit, and multichannel advantage. These…
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A major incident of dioxin contamination : sediments of New Jersey estuaries
2,3,7,8-Tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD) was measured in sediments and suspended matter samples from estuaries adjacent to an industrial site in Newark, NJ, where chlorinated phenols had…
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Laser flash photolysis of hydrogen peroxide to oxidize protein solvent-accessible residues on the microsecond timescale
  • D. Hambly, M. Gross
  • Chemistry, Biology
    Journal of the American Society for Mass…
  • 1 December 2005
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Molecular mechanism of photoactivation and structural location of the cyanobacterial orange carotenoid protein.
TLDR
An investigation on the OCP photoactivation from the cyanobacterium Synechocystis sp.
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Ionic liquids as matrixes for matrix-assisted laser desorption/ionization mass spectrometry.
TLDR
Whether their high solubalizing power, negligible vapor pressure, and broad liquid temperature range are advantageous if they are used as matrixes for UV-MALDI is examined.
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Metabolism and DNA binding studies of 4-hydroxyestradiol and estradiol-3,4-quinone in vitro and in female ACI rat mammary gland in vivo.
TLDR
Results demonstrate that the 4-CE are metabolized to CE-3,4-Q, which react with DNA to form primarily depurinating adducts, which can generate the critical mutations that initiate cancer.
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Comparing similar spectra: From similarity index to spectral contrast angle
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