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docetaxel

Known as: docetaxel hydrate, [2aR-[2a Alphaa,4beta,4a beta,6beta,9alpha,(alphaR*,betaS*),-11alpha,12alpha,12a alpha,12b alpha]]-beta-[[(1,1-dimethylethoxy)carbonyl]-amino]-alpha-hydroxybenzemepropanoic Acid 12b-(Acetyloxy)-12(benzyloxy)-2a,3,4,4a,5,6,8,10,11,12,12a,12b-dodecahydeo-4,-6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester, docetaxol 
A semi-synthetic, second-generation taxane derived from a compound found in the European yew tree, Taxus baccata. Docetaxel displays potent and broad… 
National Institutes of Health

Related topics

Related topics

41 relations
1 ML docetaxel 20 MG/ML Injection [Taxotere]Ad5CMV-p53 gene/docetaxel/doxorubicinApoptosisBCL2 protein, human

Broader (2)

Antineoplastic AgentsTaxoids

Narrower (6)

DOCETAXEL ANHYDROUSNSC 628503RP 56976RP56976

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
In Vivo Cancer Targeting of Water-Soluble Taxol by Folic Acid
Previously, folic acid receptor-targeted Dextran-Taxol-Folic acid (Dex-TXL-FA) has shown the in vitro superior and selective… 
2008
2008
The Prostate 69 : 92 ^ 104 ( 2009 ) Therapeutic Efficacyof 177 Lu-CHX-A 00-DTPA-hu 3 S 193 Radioimmunotherapy in ProstateCancer Is Enhanced by EGFRInhibitionorDocetaxel Chemotherapy
Marcus P. Kelly,* Sze Ting Lee, F.-T. Lee, Fiona E. Smyth, Ian D. Davis, Martin W. Brechbiel, and Andrew M. Scott TumourTargeting… 
2007
2007
Updated analysis of SWOG 0023: A randomized phase III trial of gefitinib versus placebo maintenance after definitive chemoradiation followed by docetaxel in patients with locally advanced stage III…
7513 Background: Early clinical studies with gefitinib (G) showed promising efficacy and mild toxicity in patients (pts) with… 
2005
2005
Bortezomib ± docetaxel in previously treated patients with advanced non-small cell lung cancer (NSCLC): A phase 2 study
7034 Background: Bortezomib (VELCADE, Vc, Millennium Pharmaceuticals), a novel proteasome inhibitor, has demonstrated activity… 
2002
2002
Taxane analogues: distinguishing royal robes from the "Emperor's New Clothes".
Whenever anticancer agents of therapeutic impact are identified, analogue development reflexively surges forward. In these… 
1999
1999
Docetaxel (taxotere) administered in weekly schedules
: The administration of a weekly low-dose taxane markedly reduces the severity of myelosuppression compared with a once-every-3… 
Highly Cited
1998
Highly Cited
1998
Phase I study of docetaxel dose escalation in combination with fixed weekly gemcitabine in patients with advanced malignancies.
PURPOSE To determine the maximum-tolerated dose of monthly docetaxel combined with fixed-dose weekly gemcitabine and describe the… 
1997
1997
Docetaxel-induced subungual hemorrhage.
Docetaxel (RP 56976 or Taxotere), a semisynthetic drug belonging to the family of taxoids, is a new chemotherapeutic agent used… 
Review
1996
Review
1996
Docetaxel: a review of its pharmacology and clinical activity.
: Docetaxel (Rhone-Poulenc Rorer Pharmaceuticals Inc.), a new and novel taxoid, is a potent antitumor agent that promotes… 
1982
1982
Embryotoxicity of benzothiazoles, benzenesulfohydrazide, and dithiodimorpholine to the chicken embryo
Benzothiazole accelerators, 2-mercaptobenzimidazole, benzenesulfohydrazide, pentachlorothiophenol, a mixture of…