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docetaxel
Known as:
docetaxel hydrate
, [2aR-[2a Alphaa,4beta,4a beta,6beta,9alpha,(alphaR*,betaS*),-11alpha,12alpha,12a alpha,12b alpha]]-beta-[[(1,1-dimethylethoxy)carbonyl]-amino]-alpha-hydroxybenzemepropanoic Acid 12b-(Acetyloxy)-12(benzyloxy)-2a,3,4,4a,5,6,8,10,11,12,12a,12b-dodecahydeo-4,-6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester
, docetaxol
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A semi-synthetic, second-generation taxane derived from a compound found in the European yew tree, Taxus baccata. Docetaxel displays potent and broad…
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National Institutes of Health
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Related topics
Related topics
41 relations
1 ML docetaxel 20 MG/ML Injection [Taxotere]
Ad5CMV-p53 gene/docetaxel/doxorubicin
Apoptosis
BCL2 protein, human
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Broader (2)
Antineoplastic Agents
Taxoids
Narrower (6)
DOCETAXEL ANHYDROUS
NSC 628503
RP 56976
RP56976
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Detection of JWH-018 metabolites in smoking mixture post-administration urine.
T. Sobolevsky
,
I. Prasolov
,
G. Rodchenkov
Forensic Science International
2010
Corpus ID: 1553387
Highly Cited
2009
Highly Cited
2009
Sunitinib malate in the treatment of recurrent or persistent uterine leiomyosarcoma: a Gynecologic Oncology Group phase II study.
M. Hensley
,
M. Sill
,
+6 authors
P. Gehrig
Gynecologic Oncology
2009
Corpus ID: 41191237
Highly Cited
2007
Highly Cited
2007
Addition of estramustine to chemotherapy and survival of patients with castration-refractory prostate cancer: a meta-analysis of individual patient data.
K. Fizazi
,
A. le Maître
,
+6 authors
S. Michiels
The Lancet Oncology
2007
Corpus ID: 32837556
Highly Cited
2006
Highly Cited
2006
Bevacizumab and weekly taxane chemotherapy demonstrates activity in refractory ovarian cancer.
D. Cohn
,
S. Valmadre
,
K. Resnick
,
L. Eaton
,
L. Copeland
,
J. Fowler
Gynecologic Oncology
2006
Corpus ID: 39133131
Review
2006
Review
2006
Salvage bevacizumab (rhuMAB VEGF)-based therapy after multiple prior cytotoxic regimens in advanced refractory epithelial ovarian cancer
B. Monk
,
E. Han
,
Carol A. Josephs-Cowan
,
Gordon Pugmire
,
R. Burger
2006
Corpus ID: 73295685
Highly Cited
2005
Highly Cited
2005
Neoadjuvant Docetaxel before Radical Prostatectomy in Patients with High-Risk Localized Prostate Cancer
P. Febbo
,
J. Richie
,
+8 authors
W. Oh
Clinical Cancer Research
2005
Corpus ID: 15145326
Purpose: To determine the clinical, pathologic, and molecular effects of neoadjuvant docetaxel chemotherapy in high-risk…
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Review
2002
Review
2002
Ovarian cancer: progress and continuing controversies in management.
C. Moss
,
S. Kaye
European Journal of Cancer
2002
Corpus ID: 44877674
Highly Cited
2001
Highly Cited
2001
Weekly docetaxel in the treatment of elderly patients with advanced breast cancer: a Minnie Pearl Cancer Research Network phase II trial.
J. Hainsworth
,
H. Burris
,
+7 authors
F. Greco
Journal of Clinical Oncology
2001
Corpus ID: 3240627
PURPOSE To evaluate the efficacy and toxicity of docetaxel administered weekly to elderly or poor-performance status patients…
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Highly Cited
1998
Highly Cited
1998
Phase I study of docetaxel with concomitant thoracic radiation therapy.
A. Mauer
,
G. Masters
,
+4 authors
E. Vokes
Journal of Clinical Oncology
1998
Corpus ID: 23435442
PURPOSE The taxanes have demonstrated activity as radiation sensitizers in preclinical studies. This study was designed to…
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Highly Cited
1994
Highly Cited
1994
Phase I study of docetaxel administered as a 1-hour intravenous infusion on a weekly basis.
E. Tomiak
,
M. Piccart
,
+7 authors
V. Auzannet
Journal of Clinical Oncology
1994
Corpus ID: 31706577
PURPOSE This phase I study of Taxotere (RP 56976, NSC 628503; docetaxel, Rhône-Poulenc Rorer, Antony, France) was undertaken to…
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