desirudin

Known as: 63-Desulfohirudin (Hirudo Medicinalis Isoform HV1), 63-Desulfohirudin, desulfatohirudin 
A synthetic recombinant form of the naturally occurring hirudin, the anticoagulant substance found in leech. Desirudin is a selective and almost… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1957-2018
0519572017

Papers overview

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1998
1998
 The present study investigates the actions of robustoxin (atracotoxin-Ar1) purified from the venom of the male Sydney funnel-web… (More)
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1997
1997
OBJECTIVE To investigate the pharmacokinetics and pharmacodynamics of desirudin in subjects with various degrees of renal… (More)
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1997
1997
Specific inhibition of thrombin is a new method for the prevention of postoperative deep-vein thrombosis. The objective of this… (More)
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1995
1995
BACKGROUND Thrombi are known to induce activation of the coagulation system, which may be a mechanism for progression of… (More)
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Highly Cited
1994
Highly Cited
1994
OBJECTIVES The purpose of this study was to assess the value of recombinant desulfatohirudin (hirudin) as adjunctive therapy to… (More)
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Highly Cited
1991
Highly Cited
1991
Recombinant desulfatohirudin (r-hirudin), a highly specific inhibitor of thrombin, was examined to determine whether it would… (More)
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1991
1991
To determine the role of thrombin in high blood flow, platelet-dependent thrombotic and hemostatic processes we measured the… (More)
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1991
1991
BACKGROUND The effectiveness of balloon angioplasty is limited by a restenosis rate of approximately 30%. Recombinant… (More)
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Highly Cited
1989
Highly Cited
1989
The effect of recombinant hirudin and the dosage of heparin on acute platelet-thrombus deposition during carotid angioplasty in… (More)
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1989
1989
The use of medicinal leeches (Hiruda medicinalis) is becoming more common after plastic surgery to control venous congestion of… (More)
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