Skip to search formSkip to main contentSkip to account menu

desirudin

Known as: 63-Desulfohirudin (Hirudo Medicinalis Isoform HV1), 63-Desulfohirudin, desulfatohirudin 
A synthetic recombinant form of the naturally occurring hirudin, the anticoagulant substance found in leech. Desirudin is a selective and almost… 
National Institutes of Health

Related topics

Related topics

7 relations

Broader (4)

AnticoagulantsFibrinolytic AgentsHirudinsRecombinant Proteins

Narrower (3)

CGP 39393IK-HIR02Revasc

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1998
1998
Individual saturated fatty acids and effects on whole blood aggregation in vitro
Objectives: In two studies we have compared the effects of four different saturated fat diets (medium chain fatty acids (MCFA… 
1993
1993
Platelet and fibrin deposition on coronary stents in minipigs: effect of hirudin versus heparin.
1992
1992
A non‐occlusive model of arterial thrombus formation in the rat and its modification by inhibitors of platelet function, or thrombin activity
A technically simple model of arterial thrombosis in the rat, induced by a crush injury to the dorsal aorta is described. The… 
1991
1991
Hirudin as anticoagulant in experimental hemodialysis.
After genetically engineered recombinant DNA desulfatohirudin (r-hirudin) had been investigated as to its pharmacokinetic… 
1990
1990
Preparation of dextran-bound recombinant hirudin and its pharmacokinetic behaviour.
Recombinant desulphatohirudin was bound via lysine residues to oxidized dextrans. The hirudin-dextran conjugates inhibit thrombin… 
Highly Cited
1989
Highly Cited
1989
Recombinant Desulphatohirudin (CGP 39393) Anticoagulant and Antithrombotic Properties In Vivo
Summary The effects of the newly available biotechnology product, recombinant desulphatohirudin (CGP 39393) have been… 
1987
1987
Isolation and characterization of recombinant desulfatohirudin from yeast, a highly selective thrombin inhibitor
Highly Cited
1986
Highly Cited
1986
Expression, secretion and processing of hirudin in E. coli using the alkaline phosphatase signal sequence
1973
1973
Osmo- und Volumenregulation beiHirudo medicinalis nach Nahrungsaufnahme
Summary1.The salt and water balance of the leech was investigated after the uptake of blood and other electrolyte solutions into… 
1957
1957
[Electron-microscopic study of the apathic neurofibrils of Hirudo medicinalis L].
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)