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desirudin

Known as: 63-Desulfohirudin (Hirudo Medicinalis Isoform HV1), 63-Desulfohirudin, desulfatohirudin 
A synthetic recombinant form of the naturally occurring hirudin, the anticoagulant substance found in leech. Desirudin is a selective and almost… Expand
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Recent studies have shown high usage of the IGHV1-69 germline immunoglobulin gene for influenza hemagglutinin stem-directed… Expand
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Highly Cited
2009
Highly Cited
2009
Voltage-dependent H(+) (Hv) channels mediate proton conduction into and out of cells under the control of membrane voltage. Hv… Expand
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Highly Cited
1997
Highly Cited
1997
A family of potent insecticidal toxins has recently been isolated from the venom of Australian funnel web spiders. Among these is… Expand
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Highly Cited
1997
Highly Cited
1997
Specific inhibition of thrombin is a new method for the prevention of postoperative deep-vein thrombosis. The objective of this… Expand
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1995
1995
BACKGROUND Thrombi are known to induce activation of the coagulation system, which may be a mechanism for progression of… Expand
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Highly Cited
1991
Highly Cited
1991
BACKGROUND The effectiveness of balloon angioplasty is limited by a restenosis rate of approximately 30%. Recombinant… Expand
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Highly Cited
1991
Highly Cited
1991
Recombinant desulfatohirudin (r-hirudin), a highly specific inhibitor of thrombin, was examined to determine whether it would… Expand
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Highly Cited
1991
Highly Cited
1991
To determine the role of thrombin in high blood flow, platelet-dependent thrombotic and hemostatic processes we measured the… Expand
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Highly Cited
1989
Highly Cited
1989
The effect of recombinant hirudin and the dosage of heparin on acute platelet-thrombus deposition during carotid angioplasty in… Expand
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1989
1989
The use of medicinal leeches (Hiruda medicinalis) is becoming more common after plastic surgery to control venous congestion of… Expand
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