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CGP 39393

Known as: CGP-39393 
 
National Institutes of Health

Papers overview

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Highly Cited
1996
Highly Cited
1996
BACKGROUND The frequency of thromboembolism after major orthopaedic surgery continues to be high despite prophylaxis. New agents… Expand
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Highly Cited
1994
Highly Cited
1994
Hirudin is an anticoagulant originally extracted from the leech Hirudo medicinalis. Using recombinant DNA technology a new… Expand
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Highly Cited
1993
Highly Cited
1993
OBJECTIVES The purpose of this study was to investigate the biologic efficacy and pharmacokinetics of different doses of… Expand
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Highly Cited
1993
Highly Cited
1993
Summary Clinical pharmacology of the intravenously administered recombinant desulfatohirudin CGP 39393 was investigated in 47… Expand
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1993
1993
The infusion of a high dose of recombinant desulphatohirudin HVI (CGP 39393) for 40 min at 30 μg/kg/min, resulted in a… Expand
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1991
1991
An existing arterio-venous shunt thrombosis model in the rat has been modified to increase its usefulness for the testing of anti… Expand
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1991
1991
The in vitro anticoagulant activities of recombinant desulphatohirudin (r-hirudin) were studied in the activated partial… Expand
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Highly Cited
1990
Highly Cited
1990
The aim of this study was to compare the ability of standard heparin and recombinant (r-)hirudin, a specific inhibitor of… Expand
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1990
1990
We studied the inhibitory action of recombinant desulphatohirudin (CGP 39393) on thrombin generation in whole plasma. Human… Expand
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1989
1989
The effects of the newly available biotechnology product, recombinant desulphatohirudin (CGP 39393) have been investigated in… Expand
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