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Prasugrel versus clopidogrel in patients with acute coronary syndromes.
- S. Wiviott, E. Braunwald, E. Antman
- Medicine, BiologyThe New England journal of medicine
- 15 November 2007
In patients with acute coronary syndromes with scheduled percutaneous coronary intervention, prasugrel therapy was associated with significantly reduced rates of ischemic events, including stent thrombosis, but with an increased risk of major bleeding, including fatal bleeding.
Third universal definition of myocardial infarction.
ACCF : American College of Cardiology Foundation ACS : acute coronary syndrome AHA : American Heart Association CAD : coronary artery disease CABG : coronary artery bypass grafting CKMB : creatine…
The TIMI risk score for unstable angina/non-ST elevation MI: A method for prognostication and therapeutic decision making.
In patients with UA/NSTEMI, the TIMI risk score is a simple prognostication scheme that categorizes a patient's risk of death and ischemic events and provides a basis for therapeutic decision making.
Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials
Edoxaban versus warfarin in patients with atrial fibrillation.
Both once-daily regimens of edoxaban were noninferior to warfarin with respect to the prevention of stroke or systemic embolism and were associated with significantly lower rates of bleeding and death from cardiovascular causes.
ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult—Summary Article
The American College of Cardiology (ACC)/AHA Task Force on Practice Guidelines regularly reviews existing guidelines to determine when an update or full revision is needed.
ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction--executive summary. A report of the American College of Cardiology/American Heart Association Task Force on…
Cytochrome p-450 polymorphisms and response to clopidogrel.
Carriers of a reduced-function CYP2C19 allele had significantly lower levels of the active metabolite of clopidogrel, diminished platelet inhibition, and a higher rate of major adverse cardiovascular events, including stent thrombosis, than did noncarriers.
Universal definition of myocardial infarction.
The document is based on the Fourth Universal Definition of Myocardial Infarction, developed jointly by experts from the European Society of Cardiology (ETC) / American College of Cardiology (ACC) /…
Myocardial infarction redefined--a consensus document of The Joint European Society of Cardiology/American College of Cardiology Committee for the redefinition of myocardial infarction.
- J. Alpert, K. Thygesen, E. Antman, J. Bassand
- MedicineJournal of the American College of Cardiology
- 30 September 2000
Biochemical markers of myocardial necrosis may have normalized, depending on the length of time that has passed since the infarct developed, and one of the following criteria satisfies the diagnosis for established MI: development of new pathologic Q waves on serial ECGs.