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deiodination

 
National Institutes of Health

Papers overview

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Review
2007
Review
2007
At least six major steps are required for secreted thyroid hormone (TH) to exert its action on target tissues. Mutations… Expand
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Review
1997
Review
1997
The realization some forty years ago that several iodothyronine compounds are present in the circulation suggested that… Expand
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Highly Cited
1996
Highly Cited
1996
In the present study we investigated the biochemical properties of in vitro phenolic (5'D) and tyrosyl (5D) ring deiodination and… Expand
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Highly Cited
1988
Highly Cited
1988
Liver is an important site for the peripheral production of T3 by outer ring deiodination (ORD) of T4 as well as for the… Expand
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Review
1984
Review
1984
THYROIDAL secretion is the only source of thyroxine (T4) in the human systemic circulation, and in euthyroid man, T4 is the main… Expand
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Highly Cited
1983
Highly Cited
1983
We have studied 5'-deiodination of thyroxine (T(4)) and 3,3',5'-triiodothyronine (rT(3)) in rat pituitary tissue in vitro, with… Expand
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Highly Cited
1983
Highly Cited
1983
In man and animals iodothyronines are metabolized by deiodination and conjugation with glucuronic acid or sulfate. Until now… Expand
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Highly Cited
1981
Highly Cited
1981
Human placental homogenate deiodinates the tyrosyl ring of T4 and T3, converting these active thyroid hormones to the inactive… Expand
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Highly Cited
1980
Highly Cited
1980
Renal membranes (crude microsomal fraction) which catalyze the thiol-dependent outer ring deiodination of LT4 with the formation… Expand
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Highly Cited
1980
Highly Cited
1980
Conversion of thyroxine (T(4)) to 3,5,3'-triiodothyronine (T(3)) in rat brain has recently been shown in in vivo studies. This… Expand
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