deiodination

 
National Institutes of Health

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2010
2010
BACKGROUND Therapy with tyrosine kinase inhibitors is associated with thyroid dysfunction. Decreased serum thyroid hormone levels… (More)
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Review
2007
Review
2007
At least six major steps are required for secreted thyroid hormone (TH) to exert its action on target tissues. Mutations… (More)
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Review
2006
Review
2006
Because the avian thyroid gland secretes almost exclusively thyroxine (T4), the availability of receptor-active 3,3',5… (More)
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Review
1997
Review
1997
The realization some forty years ago that several iodothyronine compounds are present in the circulation suggested that… (More)
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1996
1996
In the present study we investigated the biochemical properties of in vitro phenolic (5'D) and tyrosyl (5D) ring deiodination and… (More)
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1996
1996
Placental deiodination of T4 to rT3 has been proposed as the factor controlling materno-fetal transmission of T4. We investigated… (More)
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1988
1988
Liver is an important site for the peripheral production of T3 by outer ring deiodination (ORD) of T4 as well as for the… (More)
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1983
1983
In man and animals iodothyronines are metabolized by deiodination and conjugation with glucuronic acid or sulfate. Until now… (More)
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1983
1983
We have studied 5'-deiodination of thyroxine (T(4)) and 3,3',5'-triiodothyronine (rT(3)) in rat pituitary tissue in vitro, with… (More)
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1980
1980
Conversion of thyroxine (T(4)) to 3,5,3'-triiodothyronine (T(3)) in rat brain has recently been shown in in vivo studies. This… (More)
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