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dehydroretronecine

Known as: 6,7-dihydro-7-hydroxy-1-hydroxymethyl-5H-pyrrolizine, dehydro-retronecine, dehydroretro-necine 
 
National Institutes of Health

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2013
2013
A series of novel hybrid spiro heterocycles comprising pyrrolizine, spiroxindole and piperidine moieties was synthesized chemo… Expand
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2005
2005
Retronecine-based pyrrolizidine alkaloids, such as riddelliine, retrorsine, and monocrotaline, are toxic to domestic livestock… Expand
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1982
1982
Dehydroretronecine, an antimitotic and carcinogenic agent, reacted with deoxyguanosine at pH 7.4 in vitro to yield in nearly… Expand
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1982
1982
Rates of alkaline hydrolysis of 18 natural or semisynthetic pyrrolizidine alkaloids, all retronecine diesters, have been compared… Expand
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1978
1978
Monocrotaline was placed in the drinking water of rats at a concentration of 20 mg per liter for periods of up to three weeks… Expand
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1978
1978
Female Swiss mice susceptible to skin tumors received 6 sc injections and/or topical applications of dehydroretronecine, a… Expand
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1976
1976
Male Sprague-Dawley rats received sc injections biweekly of either the pyrrolizidine alkaloid monocrotaline or its metabolite… Expand
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1976
1976
The covalent interaction of dehydroretronecine, a carcinogenic metabolite of the pyrrolizidine alkaloid monocrotaline, with… Expand
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1976
1976
62 pyrrolizidine alkaloids and derivatives have been screened for acute and chronic hepato- and pneumotoxicity by the single dose… Expand
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1975
1975
Two groups of rat were given s.c. injections of either monocrotaline or its major detectable metabolite, dehydroretronecine… Expand
  • table I
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