dehydroretronecine

Known as: 6,7-dihydro-7-hydroxy-1-hydroxymethyl-5H-pyrrolizine, dehydro-retronecine, dehydroretro-necine 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1973-2016
012319732016

Papers overview

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1989
1989
New procedures are described for converting unsaturated pyrrolizidine alkaloids to chemically reactive pyrrolic esters (dehydro… (More)
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1988
1988
Dehydroretronecine (DHR), a major metabolite of the pyrrolizidine alkaloids, has been shown to bind and crosslink pBR322 plasmid… (More)
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1983
1983
A method is described for detecting alkylation of nucleophiles by dehydroretronecine (DHR) in vitro: whereas DHR is rapidly… (More)
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1982
1982
Dehydroretronecine, an antimitotic and carcinogenic agent, reacted with deoxyguanosine at pH 7.4 in vitro to yield in nearly… (More)
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1981
1981
Levels of pyrrolic metabolites have been measured in the livers of rats given some pyrrolizidine alkaloids and semisynthetic… (More)
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1978
1978
Female Swiss mice susceptible to skin tumors received 6 sc injections and/or topical applications of dehydroretronecine, a… (More)
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1977
1977
The covalent interaction of dehydroretronecine, a carcinogenic metabolite of the pyrrolizidine alkaloid monocrotaline, with… (More)
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1976
1976
Male Sprague-Dawley rats received sc injections biweekly of either the pyrrolizidine alkaloid monocrotaline or its metabolite… (More)
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1975
1975
Two groups of rat were given s.c. injections of either monocrotaline or its major detectable metabolite, dehydroretronecine… (More)
  • table I
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1975
1975
In vivo and in vitro experiments have shown that the pyrrolizidine alkaloid metabolite dehydroretronecine binds readily to… (More)
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