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Multidrug Pump Inhibitors Uncover Remarkable Activity of Plant Antimicrobials
ABSTRACT Plant antimicrobials are not used as systemic antibiotics at present. The main reason for this is their low level of activity, especially against gram-negative bacteria. The reported MIC isExpand
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Synergy in a medicinal plant: antimicrobial action of berberine potentiated by 5'-methoxyhydnocarpin, a multidrug pump inhibitor.
Multidrug resistance pumps (MDRs) protect microbial cells from both synthetic and natural antimicrobials. Amphipathic cations are preferred substrates of MDRs. Berberine alkaloids, which are cationicExpand
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Molecular and Biochemical Characterization of an Enzyme Responsible for the Formation of Hypericin in St. John's Wort (Hypericum perforatum L.)*
A major gene termed Hyp-1 encoding for hypericin (HyH) biosynthesis was cloned and characterized from Hypericum perforatum (St. John's wort) cell cultures. H. perforatum leaves are widely used as anExpand
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Enantiomeric-Dependent Phytotoxic and Antimicrobial Activity of (±)-Catechin. A Rhizosecreted Racemic Mixture from Spotted Knapweed1
In this communication, we unravel part of the mystery surrounding the allelopathic capability of the noxious weed spotted knapweed ( Centaurea maculosa ). We have found that (−)-catechin is aExpand
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Biogeographical variation in community response to root allelochemistry: novel weapons and exotic invasion
Centaurea diffusa is one of the most destructive invasive weeds in the western USA and allelopathy appears to contribute to its invasiveness (Callaway & Aschehoug 2000). Here we identify a chemicalExpand
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Acute Hepatitis Associated with the Chinese Herbal Product Jin Bu Huan
Estimates of the percentage of patients using alternative medications worldwide range from 4% to 50% [1]. According to a recent U.S. survey, 34% of adult respondents used unconventional therapy andExpand
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Host plant utilization and iridoid glycoside sequestration byEuphydryas anicia (Lepidoptera: Nymphalidae)
The iridoid glycoside content of individual adultEuphydryas anicia butterflies from two Colorado populations was quantitatively determined. At one site (Red Hill), larval host plants wereCastillejaExpand
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Isoflavones as potentiators of antibacterial activity.
Isoflavones isolated from Lupinus argenteus were found to potentiate the antibacterial activity of alpha-linolenic acid, also found in the same plant. The isoflavones also potentiated the activity ofExpand
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Metabolic profiling of root exudates of Arabidopsis thaliana.
In addition to accumulating biologically active chemicals, plant roots continuously produce and secrete compounds into their immediate rhizosphere. However, the mechanisms that drive and regulateExpand
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Chemical Composition and Physical Characteristics of Unpopped Popcorn Hybrids
Abstract Kernel number, individual kernel weight, individual kernel volume, crude fat, crude protein, reducing sugars, starch content, amylose/amylopectin ratio and fatty acid composition wereExpand
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