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- Publications
- Influence
Multidrug Pump Inhibitors Uncover Remarkable Activity of Plant Antimicrobials
- G. Tegos, F. Stermitz, O. Lomovskaya, K. Lewis
- Biology, Medicine
- Antimicrobial Agents and Chemotherapy
- 1 October 2002
ABSTRACT Plant antimicrobials are not used as systemic antibiotics at present. The main reason for this is their low level of activity, especially against gram-negative bacteria. The reported MIC is… Expand
Synergy in a medicinal plant: antimicrobial action of berberine potentiated by 5'-methoxyhydnocarpin, a multidrug pump inhibitor.
- F. Stermitz, P. Lorenz, J. Tawara, L. Zenewicz, K. Lewis
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 15 February 2000
Multidrug resistance pumps (MDRs) protect microbial cells from both synthetic and natural antimicrobials. Amphipathic cations are preferred substrates of MDRs. Berberine alkaloids, which are cationic… Expand
Molecular and Biochemical Characterization of an Enzyme Responsible for the Formation of Hypericin in St. John's Wort (Hypericum perforatum L.)*
- H. Bais, R. Vepachedu, C. Lawrence, F. Stermitz, J. Vivanco
- Biology, Medicine
- Journal of Biological Chemistry
- 22 August 2003
A major gene termed Hyp-1 encoding for hypericin (HyH) biosynthesis was cloned and characterized from Hypericum perforatum (St. John's wort) cell cultures. H. perforatum leaves are widely used as an… Expand
Enantiomeric-Dependent Phytotoxic and Antimicrobial Activity of (±)-Catechin. A Rhizosecreted Racemic Mixture from Spotted Knapweed1
- H. Bais, T. S. Walker, F. Stermitz, R. Hufbauer, J. Vivanco
- Biology, Medicine
- Plant Physiology
- 1 April 2002
In this communication, we unravel part of the mystery surrounding the allelopathic capability of the noxious weed spotted knapweed ( Centaurea maculosa ). We have found that (−)-catechin is a… Expand
Biogeographical variation in community response to root allelochemistry: novel weapons and exotic invasion
- J. Vivanco, H. Bais, F. Stermitz, G. Thelen, R. Callaway
- Biology
- 1 April 2004
Centaurea diffusa is one of the most destructive invasive weeds in the western USA and allelopathy appears to contribute to its invasiveness (Callaway & Aschehoug 2000). Here we identify a chemical… Expand
Acute Hepatitis Associated with the Chinese Herbal Product Jin Bu Huan
- G. Woolf, L. Petrovic, +8 authors J. Vierling
- Medicine
- Annals of Internal Medicine
- 15 November 1994
Estimates of the percentage of patients using alternative medications worldwide range from 4% to 50% [1]. According to a recent U.S. survey, 34% of adult respondents used unconventional therapy and… Expand
Host plant utilization and iridoid glycoside sequestration byEuphydryas anicia (Lepidoptera: Nymphalidae)
- D. Gardner, F. Stermitz
- Biology, Medicine
- Journal of Chemical Ecology
- 1 December 1988
The iridoid glycoside content of individual adultEuphydryas anicia butterflies from two Colorado populations was quantitatively determined. At one site (Red Hill), larval host plants wereCastilleja… Expand
Isoflavones as potentiators of antibacterial activity.
- C. Morel, F. Stermitz, G. Tegos, K. Lewis
- Chemistry, Medicine
- Journal of agricultural and food chemistry
- 9 August 2003
Isoflavones isolated from Lupinus argenteus were found to potentiate the antibacterial activity of alpha-linolenic acid, also found in the same plant. The isoflavones also potentiated the activity of… Expand
Metabolic profiling of root exudates of Arabidopsis thaliana.
- T. S. Walker, H. Bais, K. Halligan, F. Stermitz, J. Vivanco
- Biology, Medicine
- Journal of agricultural and food chemistry
- 20 March 2003
In addition to accumulating biologically active chemicals, plant roots continuously produce and secrete compounds into their immediate rhizosphere. However, the mechanisms that drive and regulate… Expand
Chemical Composition and Physical Characteristics of Unpopped Popcorn Hybrids
- Donkeun Park, K. Allen, F. Stermitz, J. Maga
- Chemistry
- 1 December 2000
Abstract Kernel number, individual kernel weight, individual kernel volume, crude fat, crude protein, reducing sugars, starch content, amylose/amylopectin ratio and fatty acid composition were… Expand
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