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darodipine

Known as: 3,5-Pyridinedicarboxylic acid, 4-(4-benzofurazanyl)-1,4-dihydro-2,6-dimethyl-, diethyl ester 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Calcium Channel BlockersNifedipine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1995
1995
Effects of the calcium channel antagonist darodipine on ethanol withdrawal in rats.
The effect of the dihydropyridine calcium channel antagonist, darodipine, on ethanol withdrawal syndrome was examined in rats… 
1991
1991
The Preparation and Acute Antihypertensive Effects of a Nanocapsular Form of Darodipine, a Dihydropyridine Calcium Entry Blocker
We have addressed two problems associated with the use of dihydropyridine calcium entry blockers in antihypertensive therapy… 
Highly Cited
1990
Highly Cited
1990
Threshold concentrations of endothelin-1 potentiate contractions to norepinephrine and serotonin in human arteries. A new mechanism of vasospasm?
Endothelin-1 is an endothelium-derived vasoconstrictor peptide. Its circulating levels are below those known to evoke direct… 
Highly Cited
1990
Highly Cited
1990
Different Mobilization of Calcium in Endothelin‐1 -Induced Contractions in Human Arteries and Veins: Effects of Calcium Antagonists
Summary We studied the role of extra-and intracellular Ca2+ in endothelin-1 -induced contractions of the isolated human internal… 
Highly Cited
1990
Highly Cited
1990
Isradipine
SummarySynopsisIsradipine, a dihydropyridine derivative, inhibits the inward calcium flux through ‘slow’ channels of cardiac and… 
1989
1989
Cerebrovascular, biochemical, and cytoprotective effects of isradipine in laboratory animals.
1988
1988
Cardiovascular drugs and atherosclerosis: effects of calcium antagonists, beta-blockers, and nitrates on atherosclerotic characteristics of human aortic cells.
Primary cell culture derived from atherosclerotic plaque of human aorta was used to assess direct effects of calcium antagonists… 
1987
1987
Effect of the binding of isradipine and darodipine to different plasma proteins on their transfer through the rat blood-brain barrier. Drug binding to lipoproteins does not limit the transfer of drug…
Brain extraction of two calcium channel antagonists, isradipine (PN 200-110) and darodipine (PY 108-068) was investigated using… 
1987
1987
Vasopressin increases 45Ca2+ influx in rat aortic smooth muscle cells.
1985
1985
A smooth muscle cell line suitable for the study of voltage sensitive calcium channels.
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