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cytidylyl-3'-5'-guanosine

Known as: CpG Dinucleotide, CG-dinucleotide, CpG 
A dinucleotide consisting of cytosine followed by guanine.
National Institutes of Health

Related topics

Related topics

3 relations
Base SequenceCpG Islands

Broader (1)

Dinucleoside Phosphates

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Aberrant CpG island hypermethylation along multistep hepatocarcinogenesis.
Highly Cited
2002
Highly Cited
2002
Reversal of Tumor-induced Dendritic Cell Paralysis by CpG Immunostimulatory Oligonucleotide and Anti–Interleukin 10 Receptor Antibody
Progressing tumors in man and mouse are often infiltrated by dendritic cells (DCs). Deficient antitumor immunity could be related… 
Highly Cited
2002
Highly Cited
2002
An epigenetic mouse model for molecular and behavioral neuropathologies related to schizophrenia vulnerability
Reelin and glutamic acid decarboxylase (GAD)67 expressed by cortical γ-aminobutyric acid-ergic interneurons are down-regulated in… 
Highly Cited
2002
Highly Cited
2002
Epstein-barr virus-positive gastric carcinoma demonstrates frequent aberrant methylation of multiple genes and constitutes CpG island methylator phenotype-positive gastric carcinoma.
Highly Cited
1999
Highly Cited
1999
CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression.
The molecular basis of aberrant hypermethylation of CpG islands observed in a subset of human colorectal tumors is unknown. One… 
Highly Cited
1998
Highly Cited
1998
CpG DNA induces sustained IL-12 expression in vivo and resistance to Listeria monocytogenes challenge.
Vertebrates have evolved innate immune defense mechanisms that recognize and respond to structural patterns that are specific to… 
Highly Cited
1996
Highly Cited
1996
Identification of the gene FMR2, associated with FRAXE mental retardation
Five folate-sensitive fragile sites have been characterized at the molecular level (FRAXA, FRAXE, FRAXF, FRA16A and FRA11B)1–8… 
Review
1995
Review
1995
CpG islands and genes.
Highly Cited
1994
Highly Cited
1994
Purification of CpG islands using a methylated DNA binding column
CpG islands are short stretches of DNA containing a high density of non–methylated CpG dinucleotides, predominantly associated… 
Highly Cited
1989
Highly Cited
1989
CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation.
In mammals and other vertebrates, cytosine methylation in CpG sites is often negatively correlated with gene activity. Because… 
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