Skip to search formSkip to main contentSkip to account menu

cyclophosphamide/fluorouracil/methotrexate protocol

Known as: CMF Regimen, Cytoxan-Methotrexate-Fluorouracil Regimen, Cyclophosphamide/Fluorouracil/Methotrexate 
An abbreviation for a chemotherapy combination used alone or with other therapies to treat breast cancer. It is also being studied in the treatment… 
National Institutes of Health

Related topics

Related topics

7 relations

Broader (3)

Antineoplastic Combined Chemotherapy ProtocolsCyclophosphamideMethotrexate
Breast CarcinomaDaunorubicinFluorouracilVincristine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Research-Based PAM50 Subtype Predictor Identifies Higher Responses and Improved Survival Outcomes in HER2-Positive Breast Cancer in the NOAH Study
Purpose: We report a retrospective exploratory analysis of the association of the research-based prediction analysis of… 
Highly Cited
2005
Highly Cited
2005
30 years' follow up of randomised studies of adjuvant CMF in operable breast cancer: cohort study
Abstract Objective To assess the long term effectiveness of adjuvant treatment with cyclophosphamide, methotrexate, and… 
Highly Cited
2005
Highly Cited
2005
Randomized trial comparing cyclophosphamide, epirubicin, and fluorouracil with cyclophosphamide, methotrexate, and fluorouracil in premenopausal women with node-positive breast cancer: update of…
PURPOSE Certain anthracycline-containing adjuvant chemotherapy regimens are associated with improved relapse-free survival (RFS… 
Highly Cited
2002
Highly Cited
2002
HER-2 amplification and topoisomerase IIalpha gene aberrations as predictive markers in node-positive breast cancer patients randomly treated either with an anthracycline-based therapy or with…
PURPOSE The purpose of this study is to evaluate HER-2 and topoisomerase IIalpha (topo IIalpha) as candidates for predicting the… 
Review
1998
Review
1998
Cytotoxic and hormonal treatment for metastatic breast cancer: a systematic review of published randomized trials involving 31,510 women.
PURPOSE A systematic review of randomized clinical trials (RCTs) was undertaken to assess the effectiveness of medical treatment… 
Highly Cited
1992
Highly Cited
1992
Cooperation between PDGF and FGF converts slowly dividing O-2Aadult progenitor cells to rapidly dividing cells with characteristics of O- 2Aperinatal progenitor cells
We have shown previously that oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells isolated from adult rat optic nerves can… 
Review
1988
Review
1988
Identification of a subgroup of patients with breast cancer and histologically positive axillary nodes receiving adjuvant chemotherapy who may benefit from postoperative radiotherapy.
Risk factors for isolated local-regional (LR) recurrence following mastectomy for breast cancer were analyzed in a review of 627… 
Highly Cited
1981
Highly Cited
1981
Methods for the isolation of intact epithelium from the mouse intestine
Methods are described for the isolation of intact intestinal epithelium in several novel forms. The first method described is for… 
Highly Cited
1978
Highly Cited
1978
A randomized comparative trial of adriamycin versus methotrexate in combination drug therapy
A prospective randomized trial was conducted comparing the clinical response of 78 previously untreated patients with advanced… 
Review
1963
Review
1963
STUDIES ON CELL AGGREGATION: DEMONSTRATION OF MATERIALS WITH SELECTIVE CELL-BINDING ACTIVITY.
The mechanisms involved in the mutual attachments of cells and in selectivity of cell contacts are of major interest in studies… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)