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Fluorouracil
Known as:
5-Fluracil
, 5-Fluoro-2,4(1H,3H)-pyrimidinedione
, Fluouracil
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An antimetabolite fluoropyrimidine analog of the nucleoside pyrimidine with antineoplastic activity. Fluorouracil and its metabolites possess a…
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National Institutes of Health
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Related topics
Related topics
49 relations
10 ML Fluorouracil 50 MG/ML Injection
CAFVP protocol
CFP protocol
CMF-B protocol
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Narrower (20)
COFP protocol 1
Cytosafe
FCC protocol
FDV protocol
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised…
Y. Bang
,
E. Cutsem
,
+13 authors
Yoon-Koo Kang
The Lancet
2010
Corpus ID: 8825706
Highly Cited
2007
Highly Cited
2007
Cisplatin, fluorouracil, and docetaxel in unresectable head and neck cancer.
J. Vermorken
,
É. Remenár
,
+15 authors
J. Lefebvre
The New England journal of medicine
2007
Corpus ID: 8072265
BACKGROUND Phase 2 studies suggest that the standard regimen of cisplatin and fluorouracil (PF) plus docetaxel (TPF) improves…
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Review
2005
Review
2005
Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials
O. Abe
,
R. Abe
,
+332 authors
L. Martino
The Lancet
2005
Corpus ID: 7427749
Highly Cited
2004
Highly Cited
2004
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer.
H. Hurwitz
,
L. Fehrenbacher
,
+12 authors
F. Kabbinavar
The New England journal of medicine
2004
Corpus ID: 44963102
BACKGROUND Bevacizumab, a monoclonal antibody against vascular endothelial growth factor, has shown promising preclinical and…
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Highly Cited
2004
Highly Cited
2004
Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer.
T. André
,
C. Boni
,
+9 authors
A. de Gramont
The New England journal of medicine
2004
Corpus ID: 17718892
BACKGROUND The standard adjuvant treatment of colon cancer is fluorouracil plus leucovorin (FL). Oxaliplatin improves the…
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Review
2003
Review
2003
5-Fluorouracil: mechanisms of action and clinical strategies
D. Longley
,
D. Harkin
,
P. Johnston
Nature Reviews Cancer
2003
Corpus ID: 4357553
5-Fluorouracil (5-FU) is widely used in the treatment of cancer. Over the past 20 years, increased understanding of the mechanism…
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Highly Cited
2000
Highly Cited
2000
Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer.
A. de Gramont
,
A. Figer
,
+15 authors
A. Bonetti
Journal of clinical oncology : official journal…
2000
Corpus ID: 45209302
PURPOSE In a previous study of treatment for advanced colorectal cancer, the LV5FU2 regimen, comprising leucovorin (LV) plus…
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Highly Cited
2000
Highly Cited
2000
Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. Irinotecan Study Group.
L. Saltz
,
J. Cox
,
+9 authors
L. Miller
The New England journal of medicine
2000
Corpus ID: 29624845
BACKGROUND The combination of fluorouracil and leucovorin has until recently been standard therapy for metastatic colorectal…
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Highly Cited
2000
Highly Cited
2000
Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial
J. Douillard
,
D. Cunningham
,
+10 authors
P. Rougier
The Lancet
2000
Corpus ID: 41093096
Highly Cited
1990
Highly Cited
1990
Levamisole and fluorouracil for adjuvant therapy of resected colon carcinoma.
C. Moertel
,
T. Fleming
,
+7 authors
J. Glick
The New England journal of medicine
1990
Corpus ID: 20570715
Twelve hundred ninety-six patients with resected colon cancer that either was locally invasive (Stage B2) or had regional nodal…
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