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Fluorouracil
Known as:
5-Fluracil
, 5-Fluoro-2,4(1H,3H)-pyrimidinedione
, Fluouracil
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An antimetabolite fluoropyrimidine analog of the nucleoside pyrimidine with antineoplastic activity. Fluorouracil and its metabolites possess a…
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National Institutes of Health
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Related topics
Related topics
49 relations
10 ML Fluorouracil 50 MG/ML Injection
CAFVP protocol
CFP protocol
CMF-B protocol
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Narrower (19)
COFP protocol 1
Cytosafe
FCC protocol
FDV protocol
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Activity of the combination of bevacizumab (Bev) with capecitabine/irinotecan (CapIri/Bev) or capecitabine/oxaliplatin (CapOx/Bev) in advanced colorectal cancer (ACRC): A randomized phase II study of…
A. Reinacher-Schick
,
S. Kubicka
,
+7 authors
W. Schmiegel
2008
Corpus ID: 72997073
4030 Background: The combination of Bev with 5-FU/FA and irinotecan or oxaliplatin is highly active in ACRC. A recent phase III…
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2004
2004
Bevacizumab (BV) plus 5-FU/leucovorin (FU/LV) for advanced colorectal cancer (CRC) that progressed after standard chemotherapies: An NCI Treatment Referral Center trial (TRC-0301).
H X Chen
,
M. Mooney
,
+6 authors
R. Kaplan
Journal of Clinical Oncology
2004
Corpus ID: 32156391
3515 Background: The addition of bevacizumab (BV, Avastin) to IFL for untreated metastatic CRC produces survival benefit (Hurwitz…
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Highly Cited
2002
Highly Cited
2002
Early detection and treatment of skin cancer
Peter Trovitch
,
A. Gupte
,
K. Çiftçi
2002
Corpus ID: 26718424
The most deadly but less common form of skin cancer, melanoma is now the most common cancer found in women between the ages 25 to…
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Review
2001
Review
2001
Simultaneous Radiochemotherapy in Cervical Cancer: Recommendations for Chemotherapy
J. Dunst
,
G. Haensgen
Strahlentherapie und Onkologie (Print)
2001
Corpus ID: 22795166
Background: Simultaneous radiochemotherapy has recently been demonstrated to be superior to radiation alone in the treatment of…
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Highly Cited
1983
Highly Cited
1983
Microangiopathic hemolytic anemia, renal failure, and noncardiogenic pulmonary edema: a chemotherapy-induced syndrome.
J. Jolivet
,
L. Giroux
,
S. Laurin
,
J. Gruber
,
P. Bettez
,
Band Pr
Cancer treatment reports
1983
Corpus ID: 8667217
Following gastrectomy for locally advanced adenocarcinomas, three patients developed microangiopathic hemolytic anemia and renal…
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Highly Cited
1983
Highly Cited
1983
Phase I-II studies of oral tegafur (ftorafur).
F. Ansfield
,
G. J. Kallas
,
J. P. Singson
Journal of Clinical Oncology
1983
Corpus ID: 23164536
A total of 65 patients with advanced colorectal or breast cancer were given oral tegafur in the phase I study. Of these, 28…
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1981
1981
5-FU cardiotoxicity.
S. Sanani
,
Spaulding Mb
,
Masud Ar
,
R. Canty
Cancer treatment reports
1981
Corpus ID: 36836408
Highly Cited
1979
Highly Cited
1979
Effect of 5-fluorouracil on RNA metabolism in Novikoff hepatoma cells.
J. G. Cory
,
J. C. Breland
,
G. L. Carter
Cancer Research
1979
Corpus ID: 36636287
The resistance of a Novikoff hepatoma cell line (N1-S1/FdUrd) to 5-fluorouracil (FUra) was reversed by the inclusion of inosine…
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Highly Cited
1969
Highly Cited
1969
Mechanism of pyrimethamine-induced megaloblastosis in human bone marrow.
S. Waxman
,
V. Herbert
New England Journal of Medicine
1969
Corpus ID: 31901518
Abstract Megaloblastosis appeared in a patient receiving pyrimethamine. Pyrimethamine seemed to act as does the folate antagonist…
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1958
1958
Uracil antagonism and inhibition of mammary adenocarcinoma 755.
G. Elion
,
S. Bieber
,
H. Nathan
,
G. Hitchings
Cancer Research
1958
Corpus ID: 26603407
Several types of analogs of the natural pyrimidines have been tested for their ability to restrain the growth of mammary…
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