Skip to search formSkip to main contentSkip to account menu

Fluorouracil

Known as: 5-Fluracil, 5-Fluoro-2,4(1H,3H)-pyrimidinedione, Fluouracil 
An antimetabolite fluoropyrimidine analog of the nucleoside pyrimidine with antineoplastic activity. Fluorouracil and its metabolites possess a… 
National Institutes of Health

Related topics

Related topics

49 relations
10 ML Fluorouracil 50 MG/ML InjectionCAFVP protocolCFP protocolCMF-B protocol

Narrower (20)

COFP protocol 1CytosafeFCC protocolFDV protocol

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised…
Highly Cited
2007
Highly Cited
2007
Cisplatin, fluorouracil, and docetaxel in unresectable head and neck cancer.
BACKGROUND Phase 2 studies suggest that the standard regimen of cisplatin and fluorouracil (PF) plus docetaxel (TPF) improves… 
Review
2005
Review
2005
Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials
Highly Cited
2004
Highly Cited
2004
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer.
BACKGROUND Bevacizumab, a monoclonal antibody against vascular endothelial growth factor, has shown promising preclinical and… 
Highly Cited
2004
Highly Cited
2004
Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer.
BACKGROUND The standard adjuvant treatment of colon cancer is fluorouracil plus leucovorin (FL). Oxaliplatin improves the… 
Review
2003
Review
2003
5-Fluorouracil: mechanisms of action and clinical strategies
5-Fluorouracil (5-FU) is widely used in the treatment of cancer. Over the past 20 years, increased understanding of the mechanism… 
Highly Cited
2000
Highly Cited
2000
Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer.
PURPOSE In a previous study of treatment for advanced colorectal cancer, the LV5FU2 regimen, comprising leucovorin (LV) plus… 
Highly Cited
2000
Highly Cited
2000
Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. Irinotecan Study Group.
BACKGROUND The combination of fluorouracil and leucovorin has until recently been standard therapy for metastatic colorectal… 
Highly Cited
2000
Highly Cited
2000
Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial
Highly Cited
1990
Highly Cited
1990
Levamisole and fluorouracil for adjuvant therapy of resected colon carcinoma.
Twelve hundred ninety-six patients with resected colon cancer that either was locally invasive (Stage B2) or had regional nodal… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License