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cyclin-dependent protein kinase regulator activity

Known as: cyclin, cyclin-dependent protein serine/threonine kinase regulator activity 
Modulates the activity of a cyclin-dependent protein serine/threonine kinase, enzymes of the protein kinase family that are regulated through… 
National Institutes of Health

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CyclinsPCNA geneProliferating Cell Nuclear Antigencyclin-dependent protein kinase activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Abstract 1650: Discovery of AZD4573, a potent and selective inhibitor of CDK9 that enables transient target engagement for the treatment of hematologic malignancies
Cyclin-dependent kinase 9 (CDK9) is a serine/threonine kinase that regulates elongation of transcription through phosphorylation… 
2017
2017
1-1-2013 Cyclin-Dependent Kinase 2 Regulates Foxp 3 and Regulatory T Cell Function
Foxp3 is a transcription factor required for the development and function of regulatory T cells (Treg). Humans lacking functional… 
2014
2014
hnRNPA2/B1 and nELAV proteins bind to a specific U-rich element in CDK5R1 3'-UTR and oppositely regulate its expression.
2014
2014
CDK5 Contributes to Neuronal Apoptosis via Promoting MEF2D Phosphorylation in Rat Model of Intracerebral Hemorrhage
Cyclin-dependent kinase-5 (CDK5), a serine/threonine kinase which can be activated by its neuron-specific activator p35, or its… 
2010
2010
Phosphorylation of Cyclin-dependent kinase 5 at Tyrosine 15
2007
2007
Genome-wide association data highlight an aetiological role for disturbances in cyclin-dependent kinase pathways in type 2 diabetes
2006
2006
Cyclin-dependent kinase 5, Munc18a and Munc18-interacting protein 1/X11alpha protein up-regulation in Alzheimer's disease.
Besides formation of neurofibrillary tangles and neuron loss, the Alzheimer's disease brain is characterized by neuritic plaques… 
2004
2004
α‐Chimaerin exists in a functional complex with the Cdk5 kinase in brain
Highly Cited
2002
Highly Cited
2002
Cyclin-Dependent Kinase 5/p35 Contributes Synergistically with Reelin/Dab1 to the Positioning of Facial Branchiomotor and Inferior Olive Neurons in the Developing Mouse Hindbrain
Cyclin-dependent kinase 5 (Cdk5)/p35 is a serine/threonine kinase, and its activity is detected primarily in postmitotic neurons… 
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