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ciprofibrate

Known as: 2-(4-(2,2-dichlorocyclopropyl)phenoxy)2-methylpropanoic acid, 2-(P-(2,2-Dichlorocyclopropyl)Phenoxy)-2-Methylpropionic Acid, Propanoic Acid, 2-(4-(2,2-Dichlorocyclopropyl)Phenoxy)-2-Methyl- 
A fibrate derivative with antilipidemic activity.
National Institutes of Health

Related topics

Related topics

6 relations

Broader (4)

Clofibric AcidFibric AcidsHypolipidemic AgentsPeroxisome Proliferators

Narrower (2)

LipanorOroxadin

Papers overview

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Highly Cited
2005
Highly Cited
2005
Gene expression profiling of the PPAR-alpha agonist ciprofibrate in the cynomolgus monkey liver.
Fibrates, such as ciprofibrate, fenofibrate, and clofibrate, are peroxisome proliferator-activated receptor-alpha (PPARalpha… Expand
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Highly Cited
2004
Highly Cited
2004
Application of comparative functional genomics to identify best-fit mouse models to study human cancer
Genetically modified mice have been extensively used for analyzing the molecular events that occur during tumor development. In… Expand
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Highly Cited
2000
Highly Cited
2000
Peroxisome Proliferator-activated Receptor α Activators Improve Insulin Sensitivity and Reduce Adiposity*
Fibrates and glitazones are two classes of drugs currently used in the treatment of dyslipidemia and insulin resistance (IR… Expand
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Highly Cited
2000
Highly Cited
2000
Ciprofibrate therapy improves endothelial function and reduces postprandial lipemia and oxidative stress in type 2 diabetes mellitus.
BACKGROUND Exaggerated postprandial lipemia (PPL) is a factor in atherogenesis, involving endothelial dysfunction and enhanced… Expand
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Highly Cited
2000
Highly Cited
2000
Extended-release niacin vs gemfibrozil for the treatment of low levels of high-density lipoprotein cholesterol. Niaspan-Gemfibrozil Study Group.
OBJECTIVE To provide a direct comparison of agents that raise plasma levels of high-density lipoprotein cholesterol (HDL-C) to… Expand
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Highly Cited
1996
Highly Cited
1996
Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate.
Vaccinium myrtillus L. (blueberry) leaf infusions are traditionally used as a folk medicine treatment of diabetes. To further… Expand
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Highly Cited
1993
Highly Cited
1993
Cloning of a new member of the peroxisome proliferator-activated receptor gene family from mouse liver.
Peroxisome proliferators are postulated to elicit predictable pleiotropic responses in the liver by activating a peroxisome… Expand
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Highly Cited
1989
Highly Cited
1989
Evaluation of liver cell proliferation during ciprofibrate-induced hepatocarcinogenesis.
To determine if the carcinogenic potential of peroxisome proliferators is dependent upon their ability to induce cell… Expand
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Highly Cited
1986
Highly Cited
1986
Transcription regulation of peroxisomal fatty acyl-CoA oxidase and enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase in rat liver by peroxisome proliferators.
The structurally diverse peroxisome proliferators ciprofibrate, clofibrate, and bis(2-ethylhexyl) phthalate [(EtHx)2 greater than… Expand
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Highly Cited
1984
Highly Cited
1984
Inhibitory effect of antioxidants ethoxyquin and 2(3)-tert-butyl-4-hydroxyanisole on hepatic tumorigenesis in rats fed ciprofibrate, a peroxisome proliferator.
The objective of this study was to test the hypothesis that hepatocarcinogenesis by peroxisome proliferators, a novel class of… Expand
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