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ciprofibrate
Known as:
2-(4-(2,2-dichlorocyclopropyl)phenoxy)2-methylpropanoic acid
, 2-(P-(2,2-Dichlorocyclopropyl)Phenoxy)-2-Methylpropionic Acid
, Propanoic Acid, 2-(4-(2,2-Dichlorocyclopropyl)Phenoxy)-2-Methyl-
A fibrate derivative with antilipidemic activity.
National Institutes of Health
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Related topics
Related topics
6 relations
Broader (4)
Clofibric Acid
Fibric Acids
Hypolipidemic Agents
Peroxisome Proliferators
Narrower (2)
Lipanor
Oroxadin
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
Mode of action framework analysis for receptor-mediated toxicity: The peroxisome proliferator-activated receptor alpha (PPARα) as a case study
J. Corton
,
M. Cunningham
,
+7 authors
J. Klaunig
Critical Reviews in Toxicology
2014
Corpus ID: 23495366
Abstract Several therapeutic agents and industrial chemicals induce liver tumors in rodents through the activation of the…
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Review
2006
Review
2006
PPARs, Obesity, and Inflammation
R. Stienstra
,
C. Duval
,
Michael Müller
,
S. Kersten
PPAR Research
2006
Corpus ID: 12669070
The worldwide prevalence of obesity and related metabolic disorders is rising rapidly, increasing the burden on our healthcare…
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Highly Cited
2004
Highly Cited
2004
Application of comparative functional genomics to identify best-fit mouse models to study human cancer
Ju-Seog Lee
,
I. Chu
,
+4 authors
S. Thorgeirsson
Nature Genetics
2004
Corpus ID: 29766633
Genetically modified mice have been extensively used for analyzing the molecular events that occur during tumor development. In…
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Highly Cited
2000
Highly Cited
2000
Peroxisome Proliferator-activated Receptor α Activators Improve Insulin Sensitivity and Reduce Adiposity*
M. Guerre-Millo
,
P. Gervois
,
+9 authors
B. Staels
Journal of Biological Chemistry
2000
Corpus ID: 21061618
Fibrates and glitazones are two classes of drugs currently used in the treatment of dyslipidemia and insulin resistance (IR…
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Highly Cited
2000
Highly Cited
2000
Ciprofibrate therapy improves endothelial function and reduces postprandial lipemia and oxidative stress in type 2 diabetes mellitus.
M. Evans
,
R. Anderson
,
+7 authors
A. Rees
Circulation
2000
Corpus ID: 10292061
BACKGROUND Exaggerated postprandial lipemia (PPL) is a factor in atherogenesis, involving endothelial dysfunction and enhanced…
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Highly Cited
1997
Highly Cited
1997
Safety and efficacy of long-term statin-fibrate combinations in patients with refractory familial combined hyperlipidemia.
V. Athyros
,
A. Papageorgiou
,
+4 authors
A. Kontopoulos
American Journal of Cardiology
1997
Corpus ID: 35964303
Highly Cited
1994
Highly Cited
1994
Negative regulation of the human apolipoprotein A-I promoter by fibrates can be attenuated by the interaction of the peroxisome proliferator-activated receptor with its response element.
N. Vu-dac
,
K. Schoonjans
,
B. Laine
,
J. Fruchart
,
J. Auwerx
,
B. Staels
Journal of Biological Chemistry
1994
Corpus ID: 25971246
Highly Cited
1993
Highly Cited
1993
Cloning of a new member of the peroxisome proliferator-activated receptor gene family from mouse liver.
Y. Zhu
,
K. Alvares
,
Q. Huang
,
M. Rao
,
J. Reddy
Journal of Biological Chemistry
1993
Corpus ID: 31669969
Review
1990
Review
1990
Fenofibrate. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in dyslipidaemia.
J. Balfour
,
D. McTavish
,
R. Heel
Drugs
1990
Corpus ID: 195693562
Fenofibrate is a lipid-regulating drug which is structurally related to other fibric acid derivatives, such as clofibrate. At the…
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Highly Cited
1988
Highly Cited
1988
Inhibitors of cytochrome P-450-dependent arachidonic acid metabolism.
J. Capdevila
,
L. Gil
,
+4 authors
J. Falck
Archives of Biochemistry and Biophysics
1988
Corpus ID: 30610909
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