Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 217,276,110 papers from all fields of science
Search
Sign In
Create Free Account
Peroxisome Proliferators
Known as:
Proliferators, Peroxisome
, peroxisome proliferator
A class of nongenotoxic CARCINOGENS that induce the production of hepatic PEROXISOMES and induce hepatic neoplasms after long-term administration.
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
12 relations
In Blood
Peroxisome Proliferator-Activated Receptors
agonists
antagonists & inhibitors
Expand
Narrower (3)
Nafenopin
ciprofibrate
pirinixic acid
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2003
Review
2003
Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator.
P. Puigserver
,
B. Spiegelman
Endocrine reviews
2003
Corpus ID: 35074591
Investigations of biological programs that are controlled by gene transcription have mainly studied the regulation of…
Expand
Highly Cited
2000
Highly Cited
2000
Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis.
J. J. Lehman
,
P. Barger
,
A. Kovács
,
J. Saffitz
,
D. Medeiros
,
D. Kelly
Journal of Clinical Investigation
2000
Corpus ID: 26694726
Cardiac mitochondrial function is altered in a variety of inherited and acquired cardiovascular diseases. Recent studies have…
Expand
Review
1999
Review
1999
Peroxisome proliferator-activated receptors: nuclear control of metabolism.
B. Desvergne
,
W. Wahli
Endocrine reviews
1999
Corpus ID: 2586436
I. Introduction II. Molecular Aspects A. PPAR isotypes: identity, genomic organization and chromosomal localization B. DNA…
Expand
Highly Cited
1998
Highly Cited
1998
The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation
M. Ricote
,
Andrew C. Li
,
T. Willson
,
C. Kelly
,
C. Glass
Nature
1998
Corpus ID: 4421986
The peroxisome proliferator-activated receptor-γ (PPAR-γ) is a member of the nuclear receptor superfamily of ligand-dependent…
Expand
Highly Cited
1998
Highly Cited
1998
Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ
R. Nolte
,
G. Wisely
,
+7 authors
M. Milburn
Nature
1998
Corpus ID: 4367396
The peroxisome proliferator-activated receptor-γ (PPAR-γ) is a ligand-dependent transcription factor that is important in…
Expand
Highly Cited
1995
Highly Cited
1995
Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators
S. Lee
,
T. Pineau
,
+6 authors
F. Gonzalez
Molecular and Cellular Biology
1995
Corpus ID: 11845359
To gain insight into the function of peroxisome proliferator-activated receptor (PPAR) isoforms in rodents, we disrupted the…
Expand
Highly Cited
1995
Highly Cited
1995
An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma).
J. Lehmann
,
L. Moore
,
T. Smith-Oliver
,
W. Wilkison
,
T. Willson
,
S. Kliewer
Journal of Biological Chemistry
1995
Corpus ID: 12743555
Thiazolidinedione derivatives are antidiabetic agents that increase the insulin sensitivity of target tissues in animal models of…
Expand
Highly Cited
1994
Highly Cited
1994
Differential expression and activation of a family of murine peroxisome proliferator-activated receptors.
S. Kliewer
,
S. Kliewer
,
+6 authors
R. Evans
Proceedings of the National Academy of Sciences…
1994
Corpus ID: 29323064
To gain insight into the function of peroxisome proliferator-activated receptor (PPAR) isoforms in mammals, we have cloned and…
Expand
Review
1992
Review
1992
Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors
S. Kliewer
,
K. Umesono
,
D. Noonan
,
R. Heyman
,
R. Evans
Nature
1992
Corpus ID: 8458567
PEROXISOMES are cytoplasmic organelles which are important in mammals in modulation of lipid homeostasis, including the…
Expand
Highly Cited
1990
Highly Cited
1990
Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
I. Issemann
,
S. Green
Nature
1990
Corpus ID: 4306126
We have cloned a member of the steroid hormone receptor superfamily of ligand-activated transcription factors. The receptor…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
(opens in a new tab)
,
Terms of Service
(opens in a new tab)
, and
Dataset License
(opens in a new tab)
ACCEPT & CONTINUE