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Peroxisome Proliferators
Known as:
Proliferators, Peroxisome
, peroxisome proliferator
A class of nongenotoxic CARCINOGENS that induce the production of hepatic PEROXISOMES and induce hepatic neoplasms after long-term administration.
National Institutes of Health
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Related topics
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12 relations
In Blood
Peroxisome Proliferator-Activated Receptors
agonists
antagonists & inhibitors
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Nafenopin
ciprofibrate
pirinixic acid
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Peroxisome Proliferator-Activated Receptor-&ggr; Agonists Promote Differentiation and Antioxidant Defenses of Oligodendrocyte Progenitor Cells
A. Bernardo
,
D. Bianchi
,
V. Magnaghi
,
L. Minghetti
Journal of Neuropathology and Experimental…
2009
Corpus ID: 205875077
Several lines of evidence suggest that peroxisome proliferator-activated receptor-&ggr; (PPAR-&ggr;) agonists may control brain…
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Highly Cited
2009
Highly Cited
2009
FoxO1 Haploinsufficiency Protects Against High-Fat Diet–Induced Insulin Resistance With Enhanced Peroxisome Proliferator–Activated Receptor γ Activation in Adipose Tissue
Jane J Kim
,
Pingping Li
,
Jessica Huntley
,
J. Chang
,
K. Arden
,
J. Olefsky
Diabetes
2009
Corpus ID: 18213695
OBJECTIVE Forkhead box O (FoxO) transcription factors represent evolutionarily conserved targets of insulin signaling, regulating…
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Highly Cited
2007
Highly Cited
2007
PEDF induces p53-mediated apoptosis through PPAR gamma signaling in human umbilical vein endothelial cells.
Tsung-Chuan Ho
,
S.-L. Chen
,
Y. Yang
,
C.-L. Liao
,
H. Cheng
,
Y. Tsao
Cardiovascular Research
2007
Corpus ID: 24061506
Review
2007
Review
2007
Fuel economy in food‐deprived skeletal muscle: signaling pathways and regulatory mechanisms
P. Lange
,
M. Moreno
,
E. Silvestri
,
A. Lombardi
,
F. Goglia
,
A. Lanni
The FASEB Journal
2007
Corpus ID: 25123191
Energy deprivation poses a tremendous challenge to skeletal muscle. Glucose (ATP) depletion causes muscle fibers to undergo rapid…
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Highly Cited
2006
Highly Cited
2006
15 -Deoxy -Δ12,14 -prostaglandin J2 as a potential endogenous regulator of redox-sensitive transcription factors
Eun-Hee Kim
,
Y. Surh
2006
Corpus ID: 8481721
Highly Cited
2000
Highly Cited
2000
A ligand of peroxisome proliferator-activated receptor gamma, retinoids, and prevention of preneoplastic mammary lesions.
Rajendra G. Mehta
,
Elizabeth A. Williamson
,
Minu K. Patel
,
H. Koeffler
Journal of the National Cancer Institute
2000
Corpus ID: 32584651
BACKGROUND Chemoprevention of breast cancer is an active area of investigation. Recent in vivo and in vitro studies have shown…
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Highly Cited
1999
Highly Cited
1999
A New Ligand for the Peroxisome Proliferator-Activated Receptor-γ (PPAR-γ), GW7845, Inhibits Rat Mammary Carcinogenesis
N. Suh
,
Yongping Wang
,
+4 authors
M. Sporn
1999
Corpus ID: 86189146
We have tested a new ligand for peroxisome proliferator-activated receptor-gamma, GW7845, as an inhibitor of experimental mammary…
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Highly Cited
1999
Highly Cited
1999
Pro12Ala substitution in the peroxisome proliferator-activated receptor-gamma2 is not associated with type 2 diabetes.
F. Mancini
,
O. Vaccaro
,
+4 authors
V. Colantuoni
Diabetes
1999
Corpus ID: 21112524
Peroxisome proliferator-activated receptor (PPAR)-gamma is a major regulator of adipogenesis and insulin sensitivity. The PPAR…
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Review
1987
Review
1987
The effect of peroxisome proliferators on microsomal, peroxisomal, and mitochondrial enzyme activities in the liver and kidney.
J. Hawkins
,
W. Jones
,
F. Bonner
,
G. Gibson
Drug metabolism reviews (Softcover ed.)
1987
Corpus ID: 32579156
(1987). The Effect of Peroxisome Prouferators on Microsomal. Peroxisomal, and Mitochondrial Enzyme Activities in the Liver and…
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Highly Cited
1983
Highly Cited
1983
Peroxisome proliferation in primary cultures of rat hepatocytes.
T. Gray
,
B. Lake
,
J. Beamand
,
J. Foster
,
S. Gangolli
Toxicology and Applied Pharmacology
1983
Corpus ID: 20318055
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