Peroxisome Proliferators

Known as: Proliferators, Peroxisome, peroxisome proliferator 
A class of nongenotoxic CARCINOGENS that induce the production of hepatic PEROXISOMES and induce hepatic neoplasms after long-term administration.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2006
Review
2006
The three peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors of the nuclear hormone… (More)
  • figure 1
Is this relevant?
Review
1999
Review
1999
I. Introduction II. Molecular Aspects A. PPAR isotypes: identity, genomic organization and chromosomal localization B. DNA… (More)
  • figure 1
  • table 1
  • table 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Prolonged deprivation of food induces dramatic changes in mammalian metabolism, including the release of large amounts of fatty… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1998
Highly Cited
1998
The peroxisome proliferator-activated receptor-γ (PPAR-γ) is a member of the nuclear receptor superfamily of ligand-dependent… (More)
  • figure 1
  • figure 215
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Fatty acids (FAs) and their derivatives are essential cellular metabolites whose concentrations must be closely regulated. This… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Thiazolidinedione derivatives are antidiabetic agents that increase the insulin sensitivity of target tissues in animal models of… (More)
Is this relevant?
Highly Cited
1995
Highly Cited
1995
To gain insight into the function of peroxisome proliferator-activated receptor (PPAR) isoforms in rodents, we disrupted the… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Prostaglandins (PGs) of the J2 series form in vivo and exert effects on a variety of biological processes. While most of PGs… (More)
  • figure 2
  • figure 1
  • figure 3
  • figure 4
  • table 1
Is this relevant?
Highly Cited
1994
Highly Cited
1994
To gain insight into the function of peroxisome proliferator-activated receptor (PPAR) isoforms in mammals, we have cloned and… (More)
Is this relevant?
Highly Cited
1990
Highly Cited
1990
We have cloned a member of the steroid hormone receptor superfamily of ligand-activated transcription factors. The receptor… (More)
Is this relevant?