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Peroxisome Proliferators

Known as: Proliferators, Peroxisome, peroxisome proliferator 
A class of nongenotoxic CARCINOGENS that induce the production of hepatic PEROXISOMES and induce hepatic neoplasms after long-term administration.
National Institutes of Health

Papers overview

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Review
2003
Review
2003
Investigations of biological programs that are controlled by gene transcription have mainly studied the regulation of… Expand
Review
1999
Review
1999
I. Introduction II. Molecular Aspects A. PPAR isotypes: identity, genomic organization and chromosomal localization B. DNA… Expand
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Highly Cited
1998
Highly Cited
1998
The peroxisome proliferator-activated receptor-γ (PPAR-γ) is a member of the nuclear receptor superfamily of ligand-dependent… Expand
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Highly Cited
1998
Highly Cited
1998
The peroxisome proliferator-activated receptor-γ (PPAR-γ) is a ligand-dependent transcription factor that is important in… Expand
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Highly Cited
1995
Highly Cited
1995
Prostaglandins (PGs) of the J2 series form in vivo and exert effects on a variety of biological processes. While most of PGs… Expand
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Highly Cited
1995
Highly Cited
1995
To gain insight into the function of peroxisome proliferator-activated receptor (PPAR) isoforms in rodents, we disrupted the… Expand
Highly Cited
1995
Highly Cited
1995
Thiazolidinedione derivatives are antidiabetic agents that increase the insulin sensitivity of target tissues in animal models of… Expand
Highly Cited
1994
Highly Cited
1994
To gain insight into the function of peroxisome proliferator-activated receptor (PPAR) isoforms in mammals, we have cloned and… Expand
Review
1992
Review
1992
PEROXISOMES are cytoplasmic organelles which are important in mammals in modulation of lipid homeostasis, including the… Expand
Highly Cited
1990
Highly Cited
1990
We have cloned a member of the steroid hormone receptor superfamily of ligand-activated transcription factors. The receptor… Expand