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chondrocyte differentiation

The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell… 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (1)

Chondrogenesis

Narrower (2)

chondrocyte developmentchondrocyte differentiation involved in endochondral bone morphogenesis
positive regulation of chondrocyte differentiationregulation of chondrocyte differentiation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
The Signaling Pathways Involved in Chondrocyte Differentiation and Hypertrophic Differentiation
Chondrocytes communicate with each other mainly via diffusible signals rather than direct cell-to-cell contact. The chondrogenic… 
Highly Cited
2012
Highly Cited
2012
ECM stiffness primes the TGFβ pathway to promote chondrocyte differentiation
ECM stiffness enhances chondrocyte differentiation by priming cells for a potent response to TGFβ. ECM stiffness modifies the TGF… 
Review
2009
Review
2009
TGF-beta signaling in chondrocyte terminal differentiation and osteoarthritis: modulation and integration of signaling pathways through receptor-Smads.
Highly Cited
2009
Highly Cited
2009
Notch pathway regulation of chondrocyte differentiation and proliferation during appendicular and axial skeleton development
The role of Notch signaling in cartilage differentiation and maturation in vivo was examined. Conditional Notch pathway gain and… 
Highly Cited
2005
Highly Cited
2005
Increased type II collagen degradation and very early focal cartilage degeneration is associated with upregulation of chondrocyte differentiation related genes in early human articular cartilage…
OBJECTIVE Articular cartilage degeneration in osteoarthritis (OA) involves excessive degradation of extracellular matrix (ECM… 
Highly Cited
2002
Highly Cited
2002
Wnt regulation of chondrocyte differentiation
The Wnt family of growth factors are important regulators of several developmental processes including skeletogenesis. To further… 
Review
2000
Review
2000
Transcriptional mechanisms of chondrocyte differentiation.
Highly Cited
2000
Highly Cited
2000
Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188
Highly Cited
1999
Highly Cited
1999
Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed.
The Drosophila sprouty gene encodes an antagonist of FGF and EGF signaling whose expression is induced by the signaling pathways… 
Highly Cited
1994
Highly Cited
1994
Cartilage-derived morphogenetic proteins. New members of the transforming growth factor-beta superfamily predominantly expressed in long bones during human embryonic development.
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