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chondrocyte development

The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development… Expand
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

chondrocyte differentiation

Narrower (2)

chondrocyte hypertrophychondrocyte morphogenesis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Differential expression of TGF-β superfamily members and role of Smad1/5/9-signalling in chondral versus endochondral chondrocyte differentiation
Proteins of the transforming-growth-factor-β (TGF-β)-superfamily have a remarkable ability to induce cartilage and bone and the… Expand
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2014
2014
SOX9 Regulates Multiple Genes in Chondrocytes, Including Genes Encoding ECM Proteins, ECM Modification Enzymes, Receptors, and Transporters
The transcription factor SOX9 plays an essential role in determining the fate of several cell types and is a master factor in… Expand
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Highly Cited
2009
Highly Cited
2009
Chondrocyte-specific modulation of Cyp27b1 expression supports a role for local synthesis of 1,25-dihydroxyvitamin D3 in growth plate development.
The Cyp27b1 enzyme (25-hydroxyvitamin D-1alpha-hydroxylase) that converts 25-hydroxyvitamin D into the active metabolite, 1,25… Expand
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Highly Cited
2009
Highly Cited
2009
Performance of new gellan gum hydrogels combined with human articular chondrocytes for cartilage regeneration when subcutaneously implanted in nude mice.
Gellan gum is a polysaccharide that has been recently proposed by our group for cartilage tissue-engineering applications. It is… Expand
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Highly Cited
2007
Highly Cited
2007
PTHrP regulates growth plate chondrocyte differentiation and proliferation in a Gli3 dependent manner utilizing hedgehog ligand dependent and independent mechanisms.
Growth plate chondrocytes undergo a tightly regulated process of differentiation, allowing for the longitudinal growth of bones… Expand
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Highly Cited
2006
Highly Cited
2006
Vitamin D receptor in chondrocytes promotes osteoclastogenesis and regulates FGF23 production in osteoblasts.
Genomic actions induced by 1alpha25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)] are crucial for normal bone metabolism, mainly… Expand
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Highly Cited
2005
Highly Cited
2005
Maintenance of chondroitin sulfation balance by chondroitin-4-sulfotransferase 1 is required for chondrocyte development and growth factor signaling during cartilage morphogenesis
Glycosaminoglycans (GAGs) such as heparan sulfate and chondroitin sulfate are polysaccharide chains that are attached to core… Expand
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Highly Cited
2004
Highly Cited
2004
Soluble VEGF isoforms are essential for establishing epiphyseal vascularization and regulating chondrocyte development and survival.
VEGF is crucial for metaphyseal bone vascularization. In contrast, the angiogenic factors required for vascularization of… Expand
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2003
2003
Growth/differentiation factor 5 enhances chondrocyte maturation.
Growth/differentiation factor 5 (GDF5) is required for limb mesenchymal cell condensation and joint formation during… Expand
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Review
2000
Review
2000
Chondrocytes and longitudinal bone growth: the development of tibial dyschondroplasia.
Growth plate cartilage is central to the process of bone elongation. Chondrocytes originating within the resting zone of the… Expand
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