FAQ

chondrocyte development

The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1977-2018
010203019772018

Related topics

Related topics

3 relations

Broader (1)

chondrocyte differentiation

Narrower (2)

chondrocyte hypertrophychondrocyte morphogenesis

Related mentions per year

Related mentions per year

1968-2018
1960198020002020
chondrocyte development
chondrocyte differentiation
chondrocyte hypertrophy
chondrocyte morphogenesis

Papers overview

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2014
2014
SOX9 Regulates Multiple Genes in Chondrocytes, Including Genes Encoding ECM Proteins, ECM Modification Enzymes, Receptors, and Transporters
The transcription factor SOX9 plays an essential role in determining the fate of several cell types and is a master factor in… (More)
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2014
2014
Explore on the effect of ATF6 on cell growth and apoptosis in cartilage development
We previously report that BMP2 mediates mild ER stress-activated ATF6 and directly regulates XBP1S splicing in the course of… (More)
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2012
2012
BDNF alters ERK/p38 MAPK activity ratios to promote differentiation in growth plate chondrocytes.
The ERK and p38 MAPK pathways are well-known transducers of signals that regulate proliferation and differentiation, but… (More)
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2009
2009
Chondrocyte-specific modulation of Cyp27b1 expression supports a role for local synthesis of 1,25-dihydroxyvitamin D3 in growth plate development.
The Cyp27b1 enzyme (25-hydroxyvitamin D-1alpha-hydroxylase) that converts 25-hydroxyvitamin D into the active metabolite, 1,25… (More)
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2007
2007
PTHrP regulates growth plate chondrocyte differentiation and proliferation in a Gli3 dependent manner utilizing hedgehog ligand dependent and independent mechanisms.
Growth plate chondrocytes undergo a tightly regulated process of differentiation, allowing for the longitudinal growth of bones… (More)
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Highly Cited
2006
Highly Cited
2006
Vitamin D receptor in chondrocytes promotes osteoclastogenesis and regulates FGF23 production in osteoblasts.
Genomic actions induced by 1alpha25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)] are crucial for normal bone metabolism, mainly… (More)
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Highly Cited
2005
Highly Cited
2005
Maintenance of chondroitin sulfation balance by chondroitin-4-sulfotransferase 1 is required for chondrocyte development and growth factor signaling during cartilage morphogenesis.
Glycosaminoglycans (GAGs) such as heparan sulfate and chondroitin sulfate are polysaccharide chains that are attached to core… (More)
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Highly Cited
2004
Highly Cited
2004
Soluble VEGF isoforms are essential for establishing epiphyseal vascularization and regulating chondrocyte development and survival.
VEGF is crucial for metaphyseal bone vascularization. In contrast, the angiogenic factors required for vascularization of… (More)
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2003
2003
Growth/differentiation factor 5 enhances chondrocyte maturation.
Growth/differentiation factor 5 (GDF5) is required for limb mesenchymal cell condensation and joint formation during… (More)
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1994
1994
Retinoic acid is a major regulator of chondrocyte maturation and matrix mineralization.
During the process of endochondral bone formation, chondrocytes undergo a series of complex maturational changes. Our recent… (More)
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