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caveolin 1

Known as: VIP21 Protein, Caveolin-1, Vesicular Integral Membrane Protein 21 kDa 
A tyrosine phosphoprotein that plays an essential role in CAVEOLAE formation. It binds CHOLESTEROL and is involved in LIPIDS transport, membrane… 
National Institutes of Health

Related topics

Related topics

18 relations
CAV1 geneCAV2 geneCAV3 geneIn Blood

Narrower (4)

CAV1 protein, humanCav-1 protein, XenopusCav1 protein, mousecaveolin-1 (82-101)

Broader (3)

CaveolaeCaveolinsMembrane Proteins

Papers overview

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Highly Cited
2005
Highly Cited
2005
Combined c‐Myc and caveolin‐1 expression in human prostate carcinoma predicts prostate carcinoma progression
Over‐expression of the oncogene c‐Myc has been implicated in the development and progression of human prostate carcinoma. However… 
Highly Cited
2004
Highly Cited
2004
Caveolin-1 deficiency stimulates neointima formation during vascular injury.
Neointima formation is a process characterized by smooth muscle cell (SMC) proliferation and extracellular matrix deposition in… 
Highly Cited
2003
Highly Cited
2003
Development of an immunoassay for serum caveolin-1: a novel biomarker for prostate cancer.
PURPOSE Caveolin-1 (cav-1), the major protein component of caveolae, plays an important role in multiple signaling pathways… 
Highly Cited
2001
Highly Cited
2001
Caveolin-1 mediates testosterone-stimulated survival/clonal growth and promotes metastatic activities in prostate cancer cells.
Previously, we demonstrated that up-regulation of caveolin-1 (cav-1) was associated with prostate cancer metastasis, biochemical… 
Highly Cited
2001
Highly Cited
2001
Ligand-independent activation of oestrogen receptor alpha by caveolin-1.
Expression of caveolin-1 in the human mammary adenocarcinoma cell line MCF-7 causes ligand-independent concentration of oestrogen… 
Highly Cited
2000
Highly Cited
2000
Caveolin-1 Inhibits Epidermal Growth Factor-stimulated Lamellipod Extension and Cell Migration in Metastatic Mammary Adenocarcinoma Cells (MTLn3)
Caveolin-1 is a principal component of caveolae membranes that may function as a transformation suppressor. For example, the… 
Review
2000
Review
2000
Caveolae: An Alternative Membrane Transport Compartment
Caveolae are omega-shaped invaginations of the plasma membrane with a diameter of 50-100 nm. Caveolae invaginations can detach… 
Highly Cited
2000
Highly Cited
2000
Differential Expression of Caveolin-1 in Lipopolysaccharide-Activated Murine Macrophages
ABSTRACT Five reciprocal cycles of subtractive hybridization using cDNA generated from fibroblasts with normal lipopolysaccharide… 
Highly Cited
1999
Highly Cited
1999
Analysis of the CAVEOLIN-1 gene at human chromosome 7q31.1 in primary tumours and tumour-derived cell lines
We identified CAVEOLIN-1 as a candidate for a tumour suppressor gene mapping to human chromosome 7q31.1. A number of studies… 
Highly Cited
1999
Highly Cited
1999
Identification of caveolin-1 in lipoprotein particles secreted by exocrine cells
Caveolin-1 is a protein component (of relative molecular mass 22,000) of the striated coat that decorates the cytoplasmic surface… 
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