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caspase activity

OBSOLETE. Catalysis of the hydrolysis of a peptide bond on the carboxyl side of an aspartate residue. [PMID:10872455]
National Institutes of Health

Related topics

Related topics

13 relations
caspase

Narrower (11)

caspase-1 activitycaspase-10 activitycaspase-2 activitycaspase-3 activity

Broader (1)

cysteine-type endopeptidase activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Erythropoietin improved cognitive function and decreased hippocampal caspase activity in rat pups after traumatic brain injury.
UNLABELLED Traumatic brain injury (TBI) is a leading cause of acquired neurologic disability in children. Erythropoietin (EPO… 
2005
2005
Amplification loop cascade for increasing caspase activity induced by docetaxel
The hierarchy of events accompanying induction of apoptosis by the microtubule inhibitor docetaxel was investigated in HL‐60… 
2005
2005
Selective up-regulation of caspase-3 gene expression following TCR engagement.
Highly Cited
2001
Highly Cited
2001
Antiapoptotic Signaling Generated by Caspase-Induced Cleavage of RasGAP
ABSTRACT Activation of caspases 3 and 9 is thought to commit a cell irreversibly to apoptosis. There are, however, several… 
Highly Cited
2001
Highly Cited
2001
Effect of polyamine depletion on caspase activation: a study with spermine synthase-deficient cells.
Activation of the caspase proteases represents a central point in apoptosis. The requirement for spermine for the processes… 
2000
2000
Inhibition of caspase activity delays apoptosis in a transfected NS/0 myeloma cell line.
The productivity of NS/0 myeloma batch cultures is often compromised by the premature induction of apoptosis, now established to… 
Highly Cited
1999
Highly Cited
1999
Caspase involvement in the induction of apoptosis by the environmental toxicants tributyltin and triphenyltin.
Organotin compounds such as tributyltin (TBT) and triphenyltin (TPT) can kill target cells by triggering apoptosis. The mechanism… 
Highly Cited
1999
Highly Cited
1999
Inhibition of caspase activity prevents CD95‐mediated hepatic microvascular perfusion failure and restores Kupffer cell clearance capacity
Using a murine model, we studied the effect of agonistic anti‐CD95 antibodies (aCD95) on sinusoidal lining cells and a potential… 
1999
1999
Nitric oxide can function as either a killer molecule or an antiapoptotic effector in cardiomyocytes.
1999
1999
Inhibition of caspase activity does not prevent the signaling phase of apoptosis in prostate cancer cells
Caspases are a family of cysteine proteases capable of characteristically cleaving after an aspartic acid residue. Various… 
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