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caspase-3 activity

OBSOLETE. Catalysis of the cleavage at the terminal bond of the motif: Asp-Xaa-Xaa-Asp-Xaa. Enzymes with this function are members of the peptidase… 
National Institutes of Health

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Broader (1)

caspase activity
caspase-3

Papers overview

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Highly Cited
2011
Highly Cited
2011
Dietary flavanols exert different effects on antioxidant defenses and apoptosis/proliferation in Caco-2 and SW480 colon cancer cells.
Highly Cited
2008
Highly Cited
2008
Guggulsterone Inhibits Adipocyte Differentiation and Induces Apoptosis in 3T3‐L1 Cells
Objective: To determine the effects of guggulsterone (GS), the active substance in guggulipid, on apoptosis, adipogenesis, and… 
Highly Cited
2008
Highly Cited
2008
The influence of tumor necrosis factor alpha (TNF) on the secretory function of bovine corpus luteum: TNF and its receptors expression during the estrous cycle.
Highly Cited
2008
Highly Cited
2008
Selenium activates p53 and p38 pathways and induces caspase-independent cell death in cervical cancer cells
The mechanisms of sodium selenite-induced cell death in cervical carcinoma cells were studied during 24 h of exposure in the HeLa… 
Highly Cited
2006
Highly Cited
2006
The role of polyol pathway in high glucose-induced endothelial cell damages.
Highly Cited
2005
Highly Cited
2005
Regulation of Monocyte Apoptosis by the Protein Kinase Cδ-dependent Phosphorylation of Caspase-3*
Monocytes are central components of the innate immune response and normally circulate for a short period of time before… 
Highly Cited
2004
Highly Cited
2004
Midkine protects hepatocellular carcinoma cells against TRAIL‐mediated apoptosis through down‐regulation of caspase‐3 activity
It is believed that midkine (MK), a heparin‐binding growth factor, plays an important role in carcinogenesis. However, the… 
Highly Cited
2003
Highly Cited
2003
Expression of the low affinity neurotrophin receptor p75 in spinal motoneurons in a transgenic mouse model for amyotrophic lateral sclerosis
Highly Cited
2002
Highly Cited
2002
Bone morphogenetic proteins are involved in fetal kidney tissue transplantation-induced neuroprotection in stroke rats
Highly Cited
2000
Highly Cited
2000
XIAP Regulates DNA Damage-induced Apoptosis Downstream of Caspase-9 Cleavage*
The IAP (inhibitor ofapoptosis) family of anti-apoptotic proteins regulates programmed cell death. Of the six known human IAP… 
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