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carumonam

Known as: (((2-((2-(((Aminocarbonyl)oxy)methyl)-4-oxo-1-sulfo-3-azetidinyl)amino)-1-(2-amino-4-thiazolyl)-2-oxoethylidene)amino)oxy)acetic acid (2S-(2alpha,3alpha(Z)))-, (3S,4S)-3-[2-(2-aminothiazol-4-yl)-(Z)-2-carboxymethoxyiminoacetamido]-4-carbamoyloxymethyl-2-azetidinone-1-sulfonic acid 
An N-sulfo monocyclic beta-lactam antibiotic derived from sulfazecin. Carumonam has high resistance to beta-lactamases and activity against aerobic… 
National Institutes of Health

Related topics

Related topics

4 relations

Narrower (2)

AMA 1080Carumonam Sodium

Broader (1)

Aztreonam
analogs & derivatives

Papers overview

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Review
1993
Review
1993
Clinical features of Pseudomonas cepacia pneumonia in an epidemic among immunocompromised patients.
Between January 1990 and August 1991, there were 37 patients admitted to our Department of Internal Medicine with hematologic… 
1989
1989
Multiple intravenous dose pharmacokinetic study of carumonam in healthy subjects.
Steady-state pharmacokinetics of carumonam were investigated in twelve healthy adult male volunteers after 20 min intravenous… 
1988
1988
Pharmacokinetics of carumonam after single and multiple 1- and 2-g dosage regimens
The pharmacokinetics of carumonam after single and multiple intravenous administration of 1- and 2-g dosage regimens were studied… 
1988
1988
Effect of medium chain glycerides on enteral and rectal absorption of beta-lactam and aminoglycoside antibiotics.
The rat enteral and rabbit rectal models were utilized to study the effect of Capmul (medium chain glycerides) on the absorption… 
1987
1987
Carumonam enhances reactivity of Escherichia coli with mono- and polyclonal antisera to rough Escherichia coli J5
Escherichia coli O111 reacts only slightly with antiserum to its rough mutant E. coli J5 in an enzyme-linked immunosorbent assay… 
1987
1987
Pharmacokinetics and dose recommendations of carumonam in renal failure.
The pharmacokinetics of (Z)-[[[(2-aminothiazol-4-yl)[[(2S,3S)-2-(hydroxymethyl)-4-oxo-1- sulfoazetidin-3-yl]carbamoyl]methylene… 
1986
1986
Multiply resistant mutants of Enterobacter cloacae selected by beta-lactam antibiotics
Mutants of Enterobacter cloacae, selected in vitro with ceftriaxone, ceftazidime, carumonam, or aztreonam, fell into several… 
1986
1986
Disposition of carumonam (AMA-1080/Ro 17-2301), a new N-sulfonated monocyclic beta-lactam, in rats and dogs
Rats and dogs were given a single 20-mg/kg dose of [14C]carumonam intramuscularly or intravenously. In rats, the level in plasma… 
1986
1986
Colorimetric detection and spectrophotometric determination of the aminothiazolyl-alkoxyimino beta-lactams.
The 2-aminothiazolyl-4-yl-2-alkoxyiminoacetamido substituent-containing beta-lactam antibiotics (cephalosporins and monobactams… 
1985
1985
Affinity of carumonam for penicillin-binding proteins.
Direct labeling experiments with [14C]-carumonam as well as competition binding assays with [14C]-benzylpenicillin and [14C… 
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