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carumonam

Known as: (((2-((2-(((Aminocarbonyl)oxy)methyl)-4-oxo-1-sulfo-3-azetidinyl)amino)-1-(2-amino-4-thiazolyl)-2-oxoethylidene)amino)oxy)acetic acid (2S-(2alpha,3alpha(Z)))-, (3S,4S)-3-[2-(2-aminothiazol-4-yl)-(Z)-2-carboxymethoxyiminoacetamido]-4-carbamoyloxymethyl-2-azetidinone-1-sulfonic acid 
An N-sulfo monocyclic beta-lactam antibiotic derived from sulfazecin. Carumonam has high resistance to beta-lactamases and activity against aerobic… Expand
National Institutes of Health

Papers overview

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2009
2009
Our objectives were to compare the pharmacokinetics (PK) of carumonam, a monobactam, between cystic fibrosis (CF) patients and… Expand
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Highly Cited
2005
Highly Cited
2005
SummaryA plasmid-encoded β-lactamase conferring extended broad spectrum resistance including cephamycins was identified in… Expand
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2002
2002
Representative strains of Streptococcus mutans and Streptococcus sobrinus showed differences in susceptibility to members of the… Expand
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Highly Cited
1990
Highly Cited
1990
Seven extended-spectrum beta-lactamases related to TEM and four enzymes derived from SHV-1 were transferred to a common… Expand
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1988
1988
Carumonam and gentamicin were compared in a prospective, randomized study of 52 patients with complicated urinary tract… Expand
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1987
1987
Escherichia coli O111 reacts only slightly with antiserum to its rough mutant E. coli J5 in an enzyme-linked immunosorbent assay… Expand
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1987
1987
The pharmacokinetics of (Z)-[[[(2-aminothiazol-4-yl)[[(2S,3S)-2-(hydroxymethyl)-4-oxo-1- sulfoazetidin-3-yl]carbamoyl]methylene… Expand
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1986
1986
For 45-60 days four geographically separate clinical laboratories tested routine clinical bacterial isolates for susceptibility… Expand
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1986
1986
The pharmacokinetics of carumonam after a single 1,000-mg intravenous infusion (20 min) were evaluated in four groups of subjects… Expand
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1985
1985
The in vitro and in vivo antibacterial activities of carumonam (AMA-1080), a synthetic sulfazecin derivative, were compared with… Expand
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