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carumonam

Known as: (((2-((2-(((Aminocarbonyl)oxy)methyl)-4-oxo-1-sulfo-3-azetidinyl)amino)-1-(2-amino-4-thiazolyl)-2-oxoethylidene)amino)oxy)acetic acid (2S-(2alpha,3alpha(Z)))-, (3S,4S)-3-[2-(2-aminothiazol-4-yl)-(Z)-2-carboxymethoxyiminoacetamido]-4-carbamoyloxymethyl-2-azetidinone-1-sulfonic acid 
An N-sulfo monocyclic beta-lactam antibiotic derived from sulfazecin. Carumonam has high resistance to beta-lactamases and activity against aerobic… 
National Institutes of Health

Related topics

Related topics

4 relations

Narrower (2)

AMA 1080Carumonam Sodium

Broader (1)

Aztreonam
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1989
1989
Resistance of Xanthomonas maltophilia to antibiotics and the effect of beta-lactamase inhibitors.
1988
1988
Carumonam (Ro 17-2301; AMA-1080) compared with gentamicin for treatment of complicated urinary tract infections
Carumonam and gentamicin were compared in a prospective, randomized study of 52 patients with complicated urinary tract… 
1988
1988
Susceptibility of 310 nonfermentative gram-negative bacteria to aztreonam, carumonam, ciprofloxacin, ofloxacin and fleroxacin.
The susceptibility of 310 mainly clinically isolated Gram-negative nonfermenters to aztreonam, carumonam, ciprofloxacin… 
1987
1987
Carumonam enhances reactivity of Escherichia coli with mono- and polyclonal antisera to rough Escherichia coli J5
Escherichia coli O111 reacts only slightly with antiserum to its rough mutant E. coli J5 in an enzyme-linked immunosorbent assay… 
Highly Cited
1987
Highly Cited
1987
Contribution of beta-lactamase hydrolysis and outer membrane permeability to ceftriaxone resistance in Enterobacter cloacae
Mechanisms of ceftriaxone resistance were examined in Enterobacter cloacae. Clones were selected from four strains: susceptible… 
1986
1986
Pharmacokinetics of carumonam in patients with renal insufficiency
The pharmacokinetics of carumonam after a single 1,000-mg intravenous infusion (20 min) were evaluated in four groups of subjects… 
1986
1986
Comparative pharmacokinetics of carumonam and aztreonam in mice, rats, rabbits, dogs, and cynomolgus monkeys
The pharmacokinetic properties of carumonam (AMA-1080, Ro 17-2301) were studied in mice, rats, rabbits, dogs, and cynomolgus… 
1985
1985
In vitro and in vivo antibacterial activities of carumonam (AMA-1080), a new N-sulfonated monocyclic beta-lactam antibiotic
The in vitro and in vivo antibacterial activities of carumonam (AMA-1080), a synthetic sulfazecin derivative, were compared with… 
1985
1985
Affinity of carumonam for penicillin-binding proteins.
Direct labeling experiments with [14C]-carumonam as well as competition binding assays with [14C]-benzylpenicillin and [14C… 
Review
1984
Review
1984
Ceftriaxone. A review of its antibacterial activity, pharmacological properties and therapeutic use.
Ceftriaxone is a new 'third generation' semisynthetic cephalosporin with a long half-life which has resulted in a recommended… 
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