carumonam

Known as: (((2-((2-(((Aminocarbonyl)oxy)methyl)-4-oxo-1-sulfo-3-azetidinyl)amino)-1-(2-amino-4-thiazolyl)-2-oxoethylidene)amino)oxy)acetic acid (2S-(2alpha,3alpha(Z)))-, (3S,4S)-3-[2-(2-aminothiazol-4-yl)-(Z)-2-carboxymethoxyiminoacetamido]-4-carbamoyloxymethyl-2-azetidinone-1-sulfonic acid 
An N-sulfo monocyclic beta-lactam antibiotic derived from sulfazecin. Carumonam has high resistance to beta-lactamases and activity against aerobic… (More)
National Institutes of Health

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Highly Cited
1989
Highly Cited
1989
A plasmid-encoded β-lactamase conferring extended broad spectrum resistance including cephamycins was identified in aKlebsiella… (More)
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1989
1989
Concomitant concentrations of monobactam antibiotics were measured in plasma and in prostatic tissue obtained by transurethral… (More)
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1988
1988
The susceptibility of 310 mainly clinically isolated Gram-negative nonfermenters to aztreonam, carumonam, ciprofloxacin… (More)
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1988
1988
Carumonam and gentamicin were compared in a prospective, randomized study of 52 patients with complicated urinary tract… (More)
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1988
1988
The pharmacokinetics of carumonam after single and multiple intravenous administration of 1- and 2-g dosage regimens were studied… (More)
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1986
1986
The pharmacokinetic properties of carumonam (AMA-1080, Ro 17-2301) were studied in mice, rats, rabbits, dogs, and cynomolgus… (More)
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1985
1985
Direct labeling experiments with [14C]-carumonam as well as competition binding assays with [14C]-benzylpenicillin and [14C… (More)
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1985
1985
The in vitro and in vivo antibacterial activities of carumonam (AMA-1080), a synthetic sulfazecin derivative, were compared with… (More)
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1985
1985
The in vitro activities of carumonam and eight comparative antimicrobial agents were studied. MICs of carumonam were less than or… (More)
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1985
1985
The pharmacokinetics of the monobactam carumonam (Ro 17-2301) as derived from serial measurement of the concentrations of this… (More)
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