calyculin
National Institutes of Health
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The Japanese marine sponge Discodermia calyx contains a major cytotoxic compound, calyculin A, which exhibits selective…
Insulin resistance contributes importantly to the pathophysiology of type 2 diabetes mellitus. One mechanism mediating insulin…
Although proteins phosphorylated on tyrosine residues can be enriched by immunoprecipitation with anti-phosphotyrosine antibodies…
Endothelial nitric-oxide synthase (eNOS) is an important regulatory enzyme in the cardiovascular system catalyzing the production…
The activity of the endothelial nitric oxide synthase (eNOS) can be regulated independently of an increase in Ca(2+) by the…
The second messenger ceramide (N-alkylsphingosine) has been implicated in a host of cellular processes including growth arrest…
Impulses in primary afferent nerve fibers may produce short- or long-lasting modifications in spinal nociception. Here we have…