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calyculin

 
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
The Japanese marine sponge Discodermia calyx contains a major cytotoxic compound, calyculin A, which exhibits selective… Expand
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Highly Cited
2002
Highly Cited
2002
Insulin resistance contributes importantly to the pathophysiology of type 2 diabetes mellitus. One mechanism mediating insulin… Expand
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Highly Cited
2002
Highly Cited
2002
Although proteins phosphorylated on tyrosine residues can be enriched by immunoprecipitation with anti-phosphotyrosine antibodies… Expand
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Highly Cited
2002
Highly Cited
2002
Accumulating evidence indicates that expression of anaplastic lymphoma kinase (ALK), typically due to t(2;5) translocation… Expand
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Highly Cited
2001
Highly Cited
2001
Endothelial nitric-oxide synthase (eNOS) is an important regulatory enzyme in the cardiovascular system catalyzing the production… Expand
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Highly Cited
2001
Highly Cited
2001
The activity of the endothelial nitric oxide synthase (eNOS) can be regulated independently of an increase in Ca(2+) by the… Expand
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Highly Cited
1997
Highly Cited
1997
Impulses in primary afferent nerve fibers may produce short- or long-lasting modifications in spinal nociception. Here we have… Expand
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Highly Cited
1997
Highly Cited
1997
Dopamine transporters (DATs) are members of a family of Na+- and Cl−-dependent neurotransmitter transporters responsible for the… Expand
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Highly Cited
1996
Highly Cited
1996
Signal transduction pathways involved in apoptotic cell death are poorly understood, although recent studies have implicated… Expand
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Highly Cited
1990
Highly Cited
1990
The cyclic peptide hepatotoxins microcystin-LR, 7-desmethyl-microcystin-RR and nodularin are potent inhibitors of the protein… Expand
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