bufuralol

Known as: 1-(7-ethylbenzofuran-2-yl)-2-tert-butylamino-1-hydroxyethane, Bufuralolum 
 
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
Human embryonic stem cells (hESCs) may provide a cell source for functional hepatocytes for clinical applications and drug… (More)
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2010
2010
The cynomolgus monkey is used in drug metabolism studies, because of its evolutionary closeness to human, including cytochrome… (More)
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Highly Cited
2006
Highly Cited
2006
The biotransformation of prasugrel to R-138727 (2-[1-2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4-mercapto-3-piperidinylidene… (More)
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Highly Cited
2004
Highly Cited
2004
The human clearance of proton pump inhibitors (PPIs) of the substituted benzimidazole class is conducted primarily by the hepatic… (More)
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Highly Cited
1995
Highly Cited
1995
Identifying selective inhibitors of cytochrome P450 isoforms is a useful tool in defining the role of individual cytochrome P450s… (More)
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1994
1994
Bufuralol 1'-hydroxylation is a prototypical reaction catalyzed by cytochrome P450 (P450) 2D6, an enzyme known to show… (More)
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Highly Cited
1987
Highly Cited
1987
The cytochrome P-450 forms involved in debrisoquine 4-hydroxylation (P-450DB), phenacetin O-deethylation (P-450PA), S-mephenytoin… (More)
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Highly Cited
1986
Highly Cited
1986
The anti-arrhythmic quinidine has been reported to be a competitive inhibitor of the catalytic activities of human liver P-450DB… (More)
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1982
1982
Bufuralol (Ro 3 - 4787, Angium) is a non selective beta-adrenoceptor blocking drug with some degree of sympathomimetic action and… (More)
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1980
1980
The beta-blocking agent bufuralol is subject to first-pass metabolism and is eliminated from the body almost entirely by… (More)
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