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brca gene

Known as: BRCA genes, gene brca 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
As next‐generation sequencing increases access to human genetic variation, the challenge of determining clinical significance of… 
Review
2015
Review
2015
BackgroundMainstreaming genetic medicine, increased media coverage and clinical trials for BRCA mutation carriers are leading… 
2015
2015
The involvement of microRNA (miRNAs), a new class of small RNA molecules, in governing angiogenesis has been well described. Our… 
Review
2015
Review
2015
Studies indicate variant of uncertain significance (VUS) results are challenging for genetic counselors and patients, often… 
Highly Cited
2011
Highly Cited
2011
Cells that are deficient in homologous recombination, such as those that lack functional breast cancer–associated 1 (BRCA1) or… 
Highly Cited
2011
Highly Cited
2011
PURPOSE To compare the pathologic complete response (pCR) rate and relapse-free survival (RFS) and overall survival (OS) after… 
Highly Cited
2011
Highly Cited
2011
  • Malini Guha
  • Nature Biotechnology
  • 2011
  • Corpus ID: 205267931
373 development; what’s more, its exact mechanism of action remains “unknown,” says Alan Ashworth, chief executive of the… 
Review
2011
Review
2011
Purpose: Approximately 5–10% of patients who undergo genetic testing of BRCA1 and BRCA2 receive a variant of unknown significance… 
Review
2007
Review
2007
BackgroundFor individuals genetically predisposed to breast and ovarian cancer through inheritance of a mutant BRCA allele…