Skip to search formSkip to main contentSkip to account menu

BRCA2 gene

Known as: BRCC2, BRCA2 Genes, BRCA2 
A tumor suppressor gene (GENES, TUMOR SUPPRESSOR) located on human chromosome 13 at locus 13q12.3. Mutations in this gene predispose humans to breast… 
National Institutes of Health

Related topics

Related topics

29 relations
BLID geneBRCA2 Ag:PrThr:Pt:Tiss:Ord:Immune stainBRCA2 Gene MutationBRCA2 Protein

Narrower (1)

BRCA2 wt Allele

Broader (1)

brca gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Presenilin 1 Regulates Epidermal Growth Factor Receptor Turnover and Signaling in the Endosomal-Lysosomal Pathway*
Mutations in the gene encoding presenilin 1 (PS1) cause the most aggressive form of early-onset familial Alzheimer disease. In… 
Review
2004
Review
2004
From RPA to BRCA2: lessons from single-stranded DNA binding by the OB-fold.
Highly Cited
2003
Highly Cited
2003
The CHEK2*1100delC variant acts as a breast cancer risk modifier in non-BRCA1/BRCA2 multiple-case families.
The frame-shifting mutation 1100delC in the cell-cycle-checkpoint kinase 2 gene (CHEK2) has been reported to be associated with… 
Highly Cited
2002
Highly Cited
2002
Risk-reducing salpingo-oophorectomy in women with a BRCA1 or BRCA2 mutation
In the 6 years from mid-1995 to mid-2001, 177 women from the Genetics Service at Memorial Sloan-Kettering who were found to carry… 
Highly Cited
2002
Highly Cited
2002
Mutagen sensitivity of peripheral blood from women carrying a BRCA1 or BRCA2 mutation.
Highly Cited
2001
Highly Cited
2001
Large regional differences in the frequency of distinct BRCA1/BRCA2 mutations in 517 Dutch breast and/or ovarian cancer families.
Highly Cited
2000
Highly Cited
2000
Prevalence of founder BRCA1 and BRCA2 mutations among breast and ovarian cancer patients in Hungary
We have investigated the impact of BRCA1 and BRCA2 mutations that were frequently identified among Hungarian high‐risk breast… 
Highly Cited
2000
Highly Cited
2000
The CAG repeat within the androgen receptor gene in male breast cancer patients
Editor—In the December 1998 issue of Journal of Medical Genetics , four letters discussed whether or not Kenny-Caffey syndrome… 
Highly Cited
1999
Highly Cited
1999
Clinicopathologic analysis of BRCA1‐ or BRCA2‐associated hereditary breast carcinoma in Japanese women
The purpose of this investigation was to elucidate the clinicopathologic characteristics of BRCA1‐ and BRCA2‐associated… 
Highly Cited
1996
Highly Cited
1996
Cell cycle control of BRCA2.
Identifying the conditions and kinetics of the induction of BRCA2 gene expression may implicate roles for the function of the… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)