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BRCA2 Gene Mutation

Known as: BRCA2 Mutation, Mutation of the BRCA2 Gene 
A mutation that is typically a heritable, permanent change in the nucleotide sequence of the BRCA2 gene. Single nucleotide substitutions and small… 
National Institutes of Health

Related topics

Related topics

12 relations
BRCA2 geneColloid Carcinoma of the PancreasHereditary Male Breast CarcinomaHereditary Prostate Carcinoma

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Olaparib maintenance therapy in patients (pts) with a BRCA1 and/or BRCA2 mutation (BRCAm) and newly diagnosed advanced ovarian cancer (OC): SOLO1 China cohort.
5554 Background: SOLO1 (NCT01844986) is a randomized, double-blind, Phase III trial evaluating the efficacy and safety of the… 
2015
2015
Identification of a recurrent BRCA1 exon 21‐22 genomic rearrangement in Malay breast cancer patients
To the Editor: Germline mutations in BRCA1 and BRCA2 are associated with increased risk to breast and ovarian cancer and their… 
Review
2013
Review
2013
Parental origin of mutation and the risk of breast cancer in a prospective study of women with a BRCA1 or BRCA2 mutation
The objective is to estimate the risk of breast cancer in women who carry a deleterious BRCA1 or BRCA2 mutation, according to… 
2011
2011
Prospective study of breast cancer risk for mutation negative women from BRCA1 or BRCA2 mutation positive families
Published studies have reached contradictory conclusions regarding breast cancer risk for women from families segregating a BRCA1… 
Review
2010
Review
2010
Effects of ethnicity on genotype-phenotype correlations in individuals with a BRCA1 or BRCA2 mutation.
6060 Background: Genotype-phenotype correlations have yet to be established of know BRCA1/2 mutations. A recent study found that… 
2009
2009
Selected abstracts submitted to the Third International Symposium on Hereditary Breast and Ovarian Cancer
Selected abstracts submitted to the Third International Symposium on Hereditary Breast and Ovarian Cancer BRCA: Fifteen Years of… 
2008
2008
Germline TP53 mutations in BRCA1 and BRCA2 mutation-negative French Canadian breast cancer families
About 40% of French Canadian breast and/or ovarian cancer families harbor germline BRCA1 or BRCA1 mutations where common… 
Review
2008
Review
2008
Histopathological features of ‘BRCAX’ familial breast cancers in the kConFab resource
Aims: In recent years histopathology has made an important contribution to the study of familial breast cancer, largely on the… 
2008
2008
Impact of BRCA mutation status on the clinical phenotype and survival of hereditary breast cancer
Abstract #3091 Background : In a multidisciplinary program supported by the German Cancer Aid in 1996-2006 a total of 3.408 women… 
2005
2005
Sex ratio skewing of offspring in families with hereditary susceptibility to breast cancer
The function of BRCA1 is complex and includes roles in DNA damage repair, cell cycle control, regulation of transcription, and X… 
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