FAQ

BRCA2 Gene Mutation

Known as: BRCA2 Mutation, Mutation of the BRCA2 Gene 
A mutation that is typically a heritable, permanent change in the nucleotide sequence of the BRCA2 gene. Single nucleotide substitutions and small… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1998-2017
05101519982017

Related topics

Related topics

9 relations
BRCA2 geneColloid Carcinoma of the PancreasHigh Grade Ovarian Serous AdenocarcinomaPancreatic Ductal Adenocarcinoma
(More)

Related mentions per year

Related mentions per year

1977-2018
197019801990200020102020
BRCA2 Gene Mutation
BRCA2 gene
Pancreatic Ductal Adenocarcinoma
Undifferentiated Pancreatic Carcinoma
Pancreatic Hepatoid Adenocarcinoma
Colloid Carcinoma of the Pancreas

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers.
Importance The clinical management of BRCA1 and BRCA2 mutation carriers requires accurate, prospective cancer risk estimates… (More)
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2017
2017
Bilateral Oophorectomy and Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers.
Background Whether oophorectomy reduces breast cancer risk among BRCA mutation carriers is a matter of debate. We undertook a… (More)
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2017
2017
Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores
Purpose BRCA1/2 mutations increase the risk of breast and prostate cancer in men. Common genetic variants modify cancer risks for… (More)
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2016
2016
BRCA1 and BRCA2 Mutation Testing in Young Women With Breast Cancer.
IMPORTANCE BRCA testing is recommended for young women diagnosed as having breast cancer, but little is known about decisions… (More)
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2014
2014
Targeted Prostate Cancer Screening in BRCA1 and BRCA2 Mutation Carriers: Results from the Initial Screening Round of the IMPACT Study
BACKGROUND Men with germline breast cancer 1, early onset (BRCA1) or breast cancer 2, early onset (BRCA2) gene mutations have a… (More)
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2013
2013
Seeking Balance: Decision Support Needs of Women Without Cancer and a Deleterious BRCA1 or BRCA2 Mutation
Recommendations for women with a deleterious BRCA1 or BRCA2 gene mutation include complex medical approaches related to cancer… (More)
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2012
2012
Breast Cancer Incidence After Risk-Reducing Salpingo- Oophorectomy in BRCA1 and BRCA2 Mutation Carriers
Premenopausal risk-reducing salpingo-oophorectomy (RRSO) in BRCA1/2 mutation carriers effectively reduces ovarian cancer risk… (More)
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Highly Cited
2009
Highly Cited
2009
Meta-analysis of Risk Reduction Estimates Associated With Risk-Reducing Salpingo-oophorectomy in BRCA1 or BRCA2 Mutation Carriers
BACKGROUND Risk-reducing salpingo-oophorectomy (RRSO) is widely used by carriers of BRCA1 or BRCA2 (BRCA1/2) mutations to reduce… (More)
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Highly Cited
2006
Highly Cited
2006
Salpingo-oophorectomy and the risk of ovarian, fallopian tube, and peritoneal cancers in women with a BRCA1 or BRCA2 Mutation.
CONTEXT Women with BRCA1 or BRCA2 mutation are often advised to undergo preventive oophorectomy. The effectiveness of this… (More)
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2005
2005
“Social Separation” Among Women Under 40 Years of Age Diagnosed with Breast Cancer and Carrying a BRCA1 or BRCA2 Mutation
We conducted an exploratory, qualitative study investigating experiences of women who had developed breast cancer under the age… (More)
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