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bispecific antibody 2B1

Known as: MoAb 2B1 Bispecific, 2B1 Bispecific Murine MAb, BsAb 2B1 
A monoclonal antibody with potential antineoplastic activity. Specific for both the immunoglobulin G (IgG) receptor CD16 and c-erbB-2, bispecific… 
National Institutes of Health

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Broader (1)

Antibodies, Bispecific
Antigens, CD16Bispecific Monoclonal AntibodiesERBB2 protein, humanNCIt Antineoplastic Agent Terminology

Papers overview

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2007
2007
A Bispecific Recombinant Cytotoxin (DTEGF13) Targeting Human Interleukin-13 and Epidermal Growth Factor Receptors in a Mouse Xenograft Model of Prostate Cancer
Purpose: Overexpressed cytokine receptors are considered valid targets for new biologicals targeting prostate cancer. However… 
2007
2007
Mechanisms in removal of tumor by antibody
We report two preliminary trials of antibody treatment of B-cell lymphoma. Advanced lymphoma was treated with chimeric FabFc2, in… 
2006
2006
n-6 and n-3 polyunsaturated fatty acids down-regulate cytochrome P-450 2B1 gene expression induced by phenobarbital in primary rat hepatocytes.
2000
2000
Inhalation of toluene diisocyanate affects cytochrome P450 2B1 expression in rat lung
Abstract. In the lung the expression of xenobiotic-metabolizing enzymes such as cytochromes P450 (CYP) and glutathione S… 
1998
1998
Bispecific CD3 x CD19 diabody for T cell-mediated lysis of malignant human B cells.
For the treatment of minimal residual disease in patients with leukemias and malignant lymphomas, we constructed a heterodimeric… 
1998
1998
Catalytic properties of an expressed cytochrome P450 2B1 from a Wistar-Kyoto rat liver cDNA library.
Cytochrome P450 2B1 clones were isolated from a phenobarbital-induced Wistar-Kyoto (WKY) hepatic cDNA library and were found to… 
1996
1996
Activation of T cell cytotoxicity against autologous common acute lymphoblastic leukemia (cALL) blasts by CD3xCD19 bispecific antibody.
To develop an effective immunotherapy for B-lineage acute lymphoblastic leukemia (ALL), bispecific monoclonal antibodies (bsAb… 
1995
1995
Preparation of a bispecific F(ab')2 targeted to the human IL-2 receptor.
The heterodimer-forming leucine zippers Fos and Jun can efficiently mediate the formation of bispecific F(ab')2 when they are… 
1995
1995
CD8 T cell activation after intravenous administration of CD3×CD19 bispecific antibody in patients with non-Hodgkin lymphoma
A bispecific antibody directed to T and B cells (CD3×CD19 bsAb) was daily infused intravenously in escalating doses from 10 μg up… 
1993
1993
Delivery of saporin to human B-cell lymphoma using bispecific antibody: targeting via CD22 but not CD19, CD37, or immunoglobulin results in efficient killing.
A panel of bispecific F(ab')2 antibodies (BsAb) have been constructed for delivering the ribosome-inactivating protein saporin to… 
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