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binaltorphimine

Known as: BNI ligand 
National Institutes of Health

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2 relations

Broader (1)

Naltrexone
analogs & derivatives

Papers overview

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Highly Cited
2007
Highly Cited
2007
Oxycodone and morphine have distinctly different pharmacological profiles: Radioligand binding and behavioural studies in two rat models of neuropathic pain
Highly Cited
2004
Highly Cited
2004
Salvinorin A, an Active Component of the Hallucinogenic Sage Salvia divinorum Is a Highly Efficacious κ-Opioid Receptor Agonist: Structural and Functional Considerations
The diterpene salvinorin A from Salvia divinorum has recently been reported to be a high-affinity and selective κ-opioid receptor… 
Highly Cited
2001
Highly Cited
2001
Altered Responsiveness to Cocaine and Increased Immobility in the Forced Swim Test Associated with Elevated cAMP Response Element-Binding Protein Expression in Nucleus Accumbens
Drugs of abuse regulate the transcription factor cAMP response element-binding protein (CREB) in striatal regions, including the… 
Highly Cited
2000
Highly Cited
2000
Antinociceptive effects of Nigella sativa oil and its major component, thymoquinone, in mice.
Highly Cited
1998
Highly Cited
1998
Ischemic Preconditioning in the Intact Rat Heart Is Mediated by δ1- But Not μ- or κ-Opioid Receptors
Background—Our laboratory has previously shown that δ-opioid receptors are involved in the cardioprotective effect of ischemic… 
Highly Cited
1995
Highly Cited
1995
Kappa opioid inhibition of morphine and cocaine self-administration in rats
Highly Cited
1994
Highly Cited
1994
U50,488, a κ opioid receptor agonist, attenuates cocaine-induced increases in extracellular dopamine in the nucleus accumbens of rats
Highly Cited
1992
Highly Cited
1992
All three types of opioid receptors in the spinal cord are important for 2/15 Hz electroacupuncture analgesia.
Highly Cited
1992
Highly Cited
1992
Precipitation of morphine withdrawal syndrome in rats by administration of mu-, delta- and kappa-selective opioid antagonists
Highly Cited
1988
Highly Cited
1988
Nor-binaltorphimine, a highly selective kappa-opioid antagonist in analgesic and receptor binding assays.
Previously, we reported on an opioid antagonist, nor-binaltorphimine (nor-BNI), that had high selectivity for kappa opioid… 
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