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Naltrexone

Known as: 17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one, Naltrexonum, N-Cyclopropylmethylnoroxymorphone 
A noroxymorphone derivative with competitive opioid antagonistic property. Naltrexone reverses the effects of opioid analgesics by binding to the… 
National Institutes of Health

Related topics

Related topics

46 relations

Narrower (33)

10-ketonaltrexone3-carboxamido-4-hydroxynaltrexone6 beta-hydroxynaltrexone6-deoxy-6-fluoronaltrexone

Broader (2)

Heterocyclic Compounds, Bridged-RingNarcotic Antagonists
In BloodLiver FailureNaltrexone 380 MG Injection [Vivitrol]Naltrexone cutoff:MCnc:Pt:Urine:Qn:Confirm

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
Simultaneous development of six LC-MS-MS methods for the determination of multiple analytes in human plasma.
Highly Cited
1994
Highly Cited
1994
A 24-h inpatient detoxification treatment for heroin addicts: a preliminary investigation.
Highly Cited
1990
Highly Cited
1990
N--methyl-d-aspartate receptors mediate activation of the c-fos proto-oncogene in a model of brain injury
Highly Cited
1990
Highly Cited
1990
Opioid antagonist challenges in buprenorphine maintained patients.
Highly Cited
1988
Highly Cited
1988
Upregulation of opioid receptor subtypes correlates with potency changes of morphine and DADLE.
Highly Cited
1987
Highly Cited
1987
Naltrexone decreases self‐injurious behavior
The effect of naltrexone (0.5, 1.0, 1.5, and 2.0 mg/kg) on the frequency of self‐injurious behavior (SIB) was investigated in… 
Highly Cited
1982
Highly Cited
1982
Naloxone enhancement of memory processes: effects of other opiate antagonists.
Highly Cited
1981
Highly Cited
1981
Possible involvement of endorphin withdrawal or imbalance in specific premenstrual syndromes and postpartum depression.
Highly Cited
1980
Highly Cited
1980
Location and characterization of opiate receptors regulating pituitary secretion.
Highly Cited
1977
Highly Cited
1977
Opioid peptides and opiates differ in receptor selectivity
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