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Naltrexone

Known as: 17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one, Naltrexonum, N-Cyclopropylmethylnoroxymorphone 
A noroxymorphone derivative with competitive opioid antagonistic property. Naltrexone reverses the effects of opioid analgesics by binding to the… Expand
National Institutes of Health

Related topics

Related topics

46 relations

Narrower (33)

10-ketonaltrexone3-carboxamido-4-hydroxynaltrexone6 beta-hydroxynaltrexone6-deoxy-6-fluoronaltrexone
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Broader (2)

Heterocyclic Compounds, Bridged-RingNarcotic Antagonists
In BloodLiver FailureNaltrexone 380 MG Injection [Vivitrol]Naltrexone cutoff:MCnc:Pt:Urine:Qn:Confirm
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Obesity and nonalcoholic fatty liver disease: From pathophysiology to therapeutics.
The obesity epidemic is closely associated with the rising prevalence and severity of nonalcoholic fatty liver disease (NAFLD… Expand
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Review
2019
Review
2019
Medication Treatment For Opioid Use Disorders In Substance Use Treatment Facilities.
Medication treatment (MT) is one of the few evidence-based strategies proposed to combat the current opioid epidemic. We examined… Expand
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Review
2019
Review
2019
Development of a Cascade of Care for responding to the opioid epidemic
ABSTRACT Amid worsening opioid overdose death rates, the nation continues to face a persistent addiction treatment gap limiting… Expand
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Highly Cited
2005
Highly Cited
2005
Efficacy and tolerability of long-acting injectable naltrexone for alcohol dependence: a randomized controlled trial.
CONTEXT Alcohol dependence is a common disorder associated with significant morbidity and mortality. Naltrexone, an opioid… Expand
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Highly Cited
2003
Highly Cited
2003
A Functional Polymorphism of the μ-Opioid Receptor Gene is Associated with Naltrexone Response in Alcohol-Dependent Patients
This study examined the association between two specific polymorphisms of the gene encoding the μ-opioid receptor and treatment… Expand
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Highly Cited
2001
Highly Cited
2001
Naltrexone in the treatment of alcohol dependence.
BACKGROUND Although naltrexone, an opiate-receptor antagonist, has been approved by the Food and Drug Administration for the… Expand
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Highly Cited
2001
Highly Cited
2001
Double-blind naltrexone and placebo comparison study in the treatment of pathological gambling
BACKGROUND The authors' goal was to assess the efficacy and tolerability of naltrexone in the treatment of pathologic gambling… Expand
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Review
1994
Review
1994
Naltrexone in the treatment of alcohol dependence.
A BSTRACT Background Although naltrexone, an opiate-receptor antagonist, has been approved by the Food and Drug Administration… Expand
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Highly Cited
1992
Highly Cited
1992
Naltrexone and coping skills therapy for alcohol dependence. A controlled study.
Ninety-seven alcohol-dependent patients were treated for 12 weeks in a double-blind, placebo-controlled study evaluating… Expand
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Highly Cited
1976
Highly Cited
1976
The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog.
Three different syndromes produced by congeners of morphine have been identified in the nondependent chronic spinal dog. These… Expand
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