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Naltrexone

Known as: 17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one, Naltrexonum, N-Cyclopropylmethylnoroxymorphone 
A noroxymorphone derivative with competitive opioid antagonistic property. Naltrexone reverses the effects of opioid analgesics by binding to the… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
The obesity epidemic is closely associated with the rising prevalence and severity of nonalcoholic fatty liver disease (NAFLD… Expand
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Review
2019
Review
2019
Medication treatment (MT) is one of the few evidence-based strategies proposed to combat the current opioid epidemic. We examined… Expand
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Review
2019
Review
2019
ABSTRACT Amid worsening opioid overdose death rates, the nation continues to face a persistent addiction treatment gap limiting… Expand
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Highly Cited
2005
Highly Cited
2005
CONTEXT Alcohol dependence is a common disorder associated with significant morbidity and mortality. Naltrexone, an opioid… Expand
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Highly Cited
2003
Highly Cited
2003
This study examined the association between two specific polymorphisms of the gene encoding the μ-opioid receptor and treatment… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Although naltrexone, an opiate-receptor antagonist, has been approved by the Food and Drug Administration for the… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND The authors' goal was to assess the efficacy and tolerability of naltrexone in the treatment of pathologic gambling… Expand
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Review
1994
Review
1994
A BSTRACT Background Although naltrexone, an opiate-receptor antagonist, has been approved by the Food and Drug Administration… Expand
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Highly Cited
1992
Highly Cited
1992
Ninety-seven alcohol-dependent patients were treated for 12 weeks in a double-blind, placebo-controlled study evaluating… Expand
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Highly Cited
1976
Highly Cited
1976
Three different syndromes produced by congeners of morphine have been identified in the nondependent chronic spinal dog. These… Expand
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