autophagosome assembly

Known as: autophagosome formation, autophagosome biosynthesis, autophagic vacuole assembly 
The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Autophagy is a bulk degradation process in eukaryotic cells and has fundamental roles in cellular homeostasis.The origin and… (More)
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Highly Cited
2008
Highly Cited
2008
Autophagy is the engulfment of cytosol and organelles by double-membrane vesicles termed autophagosomes. Autophagosome formation… (More)
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Highly Cited
2008
Highly Cited
2008
Autophagy is a potent intracellular degradation process with pivotal roles in health and disease. Atg8, a lipid-conjugated… (More)
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Highly Cited
2008
Highly Cited
2008
Autophagy is a membrane-mediated intracellular degradation system. The serine/threonine kinase Atg1 plays an essential role in… (More)
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Highly Cited
2008
Highly Cited
2008
Autophagic and endocytic pathways are tightly regulated membrane rearrangement processes that are crucial for homeostasis… (More)
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Highly Cited
2007
Highly Cited
2007
Autophagy involves de novo formation of double membrane-bound structures called autophagosomes, which engulf material to be… (More)
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Review
2002
Review
2002
Macroautophagy is an intracellular degradation system for the majority of proteins and some organelles. The molecular mechanism… (More)
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Highly Cited
2001
Highly Cited
2001
In macroautophagy, cytoplasmic components are delivered to lysosomes for degradation via autophagosomes that are formed by… (More)
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Highly Cited
2001
Highly Cited
2001
Macroautophagy is a bulk degradation process induced by starvation in eukaryotic cells. In yeast, 15 Apg proteins coordinate the… (More)
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Highly Cited
1999
Highly Cited
1999
We characterized Apg8/Aut7p essential for autophagy in yeast. Apg8p was transcriptionally upregulated in response to starvation… (More)
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