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arcaine

Known as: 1,4-diguanidinobutane, tetramethylenediguanide 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Biguanides

Narrower (1)

arcaine, dihydrochloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Spermidine improves fear memory persistence.
2010
2010
Polyaminergic agents modulate contextual fear extinction in rats
2005
2005
Pronociceptive role of dynorphins in uninjured animals: N-ethylmaleimide-induced nociceptive behavior mediated through inhibition of dynorphin degradation
Highly Cited
2001
Highly Cited
2001
Intra-amygdala spermidine administration improves inhibitory avoidance performance in rats.
1996
1996
Characterisation of a functional polyamine site on rat mast cells: association with a NMDA receptor macrocomplex
Highly Cited
1994
Highly Cited
1994
Further characterization of [3H]ifenprodil binding in rat brain.
Highly Cited
1994
Highly Cited
1994
N-methyl-d-aspartate receptor-mediated changes in thermal nociception: Allosteric modulation at glycine and polyamine recognition sites
1992
1992
Polyamines allosterically modulate [3H]nitrendipine binding to the voltage-sensitive calcium channel in rat brain.
Highly Cited
1992
Highly Cited
1992
Arcaine blocks N-methyl-D-aspartate receptor responses by an open channel mechanism: whole-cell and single-channel recording studies in cultured hippocampal neurons.
Arcaine, a putative competitive antagonist at the polyamine site on the N-methyl-D-aspartate (NMDA) receptor complex, not only… 
Highly Cited
1990
Highly Cited
1990
Arcaine uncovers dual interactions of polyamines with the N-methyl-D-aspartate receptor.
This study investigated the interaction between the polyamines spermine and spermidine and the N-methyl-D-aspartate (NMDA… 
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