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arcaine

Known as: 1,4-diguanidinobutane, tetramethylenediguanide 
 
National Institutes of Health

Papers overview

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2008
2008
RationaleThe polyamines putrescine, spermidine, and spermine are a group of aliphatic amines that may act as physiological… Expand
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2006
2006
Putrescine, a polyamine present at high concentrations in the mammalian brain, was suggested to play a role in the modulation of… Expand
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Highly Cited
2006
Highly Cited
2006
Agmatine is a polyamine and has been considered as a novel neurotransmitter or neuromodulator in the central nervous system. In… Expand
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Highly Cited
2004
Highly Cited
2004
Polyamines, among other functions, are considered to act as a free radical scavenger and antioxidant. The quinolinic acid (QA… Expand
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2002
2002
Ifenprodil, arcaine and agmatine have all been reported to inhibit the NMDA receptor by actions at polyamine-sites, however the… Expand
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Highly Cited
1999
Highly Cited
1999
We investigated in rat hippocampus neurons whether 4-(aminobutyl)guanidine (agmatine), formed by decarboxylation of L-arginine by… Expand
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1999
1999
Polyamines such as spermine are thought to be endogenous regulators of NMDA (N-methyl-D-aspartate)-type glutamate receptors… Expand
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1998
1998
Abstract The discriminative stimulus properties of compounds that interact with the NMDA receptor complex were investigated in… Expand
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Highly Cited
1998
Highly Cited
1998
It has been suggested that the anticraving drug, acamprosate, acts via the glutamatergic system, but the exact mechanism of… Expand
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1990
1990
  • Ian Reynolds
  • The Journal of pharmacology and experimental…
  • 1990
  • Corpus ID: 19391897
This study investigated the interaction between the polyamines spermine and spermidine and the N-methyl-D-aspartate (NMDA… Expand
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