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Biguanides

Known as: Biguanide, Biguanides [Chemical/Ingredient] 
Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES… 
National Institutes of Health

Related topics

Related topics

33 relations

Narrower (18)

1-(3-chlorophenyl)biguanide2,4-dimethoxyphenyl biguanide2-tolylbiguanide3,4-dichlorophenylbiguanide
24 HR Metformin hydrochloride 500 MG Extended Release Oral TabletBiguanide [EPC]In BloodMetformin

Broader (1)

Hypoglycemic Agents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Metformin: the hidden chronicles of a magic drug.
Highly Cited
2010
Highly Cited
2010
Lipophilic versus hydrodynamic modes of uptake and release by contact lenses of active entities used in multipurpose solutions.
Review
2004
Review
2004
A comparison of the effects of thiazolidinediones and metformin on metabolic control in patients with type 2 diabetes mellitus.
Highly Cited
2004
Highly Cited
2004
Association of diabetes mellitus and glycemic control strategies with clinical outcomes after acute coronary syndromes.
Review
2002
Review
2002
The pathophysiologic basis of efficacy and clinical experience with the new oral antidiabetic agents.
Highly Cited
1993
Highly Cited
1993
Excitatory amino acid receptors in the nucleus tractus solitarius mediate the responses to the stimulation of cardio-pulmonary vagal afferent C fiber endings
Highly Cited
1991
Highly Cited
1991
The activation of the biguanide antimalarial proguanil co-segregates with the mephenytoin oxidation polymorphism--a panel study.
The activation of the antimalarial drug proguanil (PG) to the active metabolite cycloguanil (CG) has been evaluated in a panel of… 
Highly Cited
1985
Highly Cited
1985
Metformin improved insulin resistance in type I, insulin-dependent, diabetic patients.
Highly Cited
1984
Highly Cited
1984
New polymeric biocides: synthesis and antibacterial activities of polycations with pendant biguanide groups
Acrylate monomers with pendant biguanide groups were successfully synthesized, and their homopolymers and copolymers were… 
Highly Cited
1978
Highly Cited
1978
Pharmacologic profile of methyl 2-tetradecylglycidate (McN-3716)--an orally effective hypoglycemic agent.
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