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Biguanides

Known as: Biguanide, Biguanides [Chemical/Ingredient] 
Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES… 
National Institutes of Health

Related topics

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33 relations

Narrower (18)

1-(3-chlorophenyl)biguanide2,4-dimethoxyphenyl biguanide2-tolylbiguanide3,4-dichlorophenylbiguanide
24 HR Metformin hydrochloride 500 MG Extended Release Oral TabletBiguanide [EPC]In BloodMetformin

Broader (1)

Hypoglycemic Agents

Papers overview

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Review
2013
Review
2013
Metformin: the hidden chronicles of a magic drug.
Review
2004
Review
2004
A comparison of the effects of thiazolidinediones and metformin on metabolic control in patients with type 2 diabetes mellitus.
2003
2003
Effects of phenformin on the proliferation of human tumor cell lines.
Highly Cited
1994
Highly Cited
1994
Effects of the biguanide class of oral hypoglycemic agents on mouse embryogenesis.
The incidence of birth defects among offspring of mothers with non-insulin dependent diabetes mellitus (NIDDM) is 2-3-fold higher… 
Highly Cited
1990
Highly Cited
1990
Synergism within polyhexamethylene biguanide biocide formulations.
Polyhexamethylene biguanides (PHMB) are mixtures of polymeric biguanides with an average polymer length (n) of 5, but containing… 
1989
1989
Neural reflex of the canine pylorus to intraduodenal acid infusion.
Highly Cited
1981
Highly Cited
1981
Biguanide treatment increases the number of insulin-receptor sites on human erythrocytes.
THE mode of the antihyperglycemic action of biguanides has been in dispute for many years. Increased muscular uptake of glucose… 
Highly Cited
1978
Highly Cited
1978
Pharmacologic profile of methyl 2-tetradecylglycidate (McN-3716)--an orally effective hypoglycemic agent.
1977
1977
Treatment of hypertriglyceridemia with metformin. Effectiveness and analỳsis of results.
Highly Cited
1973
Highly Cited
1973
Effect on dental plaque formation and some in vitro properties of 12 bis-biguanides.
Six alkyl-, 4 alicyclie- and 2 aryl-bis-biguanide formulations have been tested for plaque inhibition in vivo. The participants… 
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