Biguanides

Known as: Biguanide, Biguanides [Chemical/Ingredient] 
Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES… (More)
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
As the concentrations of highly consumed nutrients, particularly glucose, are generally lower in tumours than in normal tissues… (More)
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Highly Cited
2014
Highly Cited
2014
The biguanide metformin is widely prescribed for Type II diabetes and has anti-neoplastic activity in laboratory models. Despite… (More)
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Highly Cited
2013
Highly Cited
2013
Glucose production by the liver is essential for providing a substrate for the brain during fasting. The inability of insulin to… (More)
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Review
2013
Review
2013
Metformin is widely prescribed for the treatment of type II diabetes. Recently, it has been proposed that this compound or… (More)
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Review
2010
Review
2010
Retrospective studies that may be impractical to confirm prospectively suggest that diabetics treated with metformin have a… (More)
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Highly Cited
2010
Highly Cited
2010
Dysfunctional mTORC1 signaling is associated with a number of human pathologies owing to its central role in controlling cell… (More)
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Highly Cited
2010
Highly Cited
2010
Hyperphosphorylated tau plays an important role in the formation of neurofibrillary tangles in brains of patients with Alzheimer… (More)
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Highly Cited
2009
Highly Cited
2009
This report presents an algorithm to assist primary care physicians, endocrinologists, and others in the management of adult… (More)
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Review
2005
Review
2005
Type 2 diabetes mellitus is a progressive and complex disorder that is difficult to treat effectively in the long term. The… (More)
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Review
2002
Review
2002
Insulin resistance contributes greatly to development of cardiovascular disease in patients with the metabolic syndrome and its… (More)
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