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The Montreal Definition and Classification of Gastroesophageal Reflux Disease: A Global Evidence-Based Consensus
Novel aspects of the new definition include a patient-centered approach that is independent of endoscopic findings, subclassification of the disease into discrete syndrome, and the recognition of laryngitis, cough, asthma, and dental erosions as possible GERD syndromes. Expand
Epidemiology of gastro-oesophageal reflux disease: a systematic review
The prevalence and incidence of gastro-oesophageal reflux disease was estimated from 15 studies which defined GORD as at least weekly heartburn and/or acid regurgitation and met criteria concerning sample size, response rate, and recall period. Expand
Update on the epidemiology of gastro-oesophageal reflux disease: a systematic review
GERD is prevalent worldwide, and disease burden may be increasing, and prevalence estimates show considerable geographic variation, but only East Asia shows estimates consistently lower than 10%. Expand
Endoscopic assessment of oesophagitis: clinical and functional correlates and further validation of the Los Angeles classification
Results add further support to previous studies for the clinical utility of the Los Angeles system for endoscopic grading of oesophagitis and to the risk for symptom relapse off therapy over six months. Expand
An evidence-based appraisal of reflux disease management — the Genval Workshop Report
This report summarises conclusions from an evidence-based workshop which evaluated major clinical strategies for the management of the full spectrum of gastro-oesophageal reflux disease, with anExpand
Mechanism of gastroesophageal reflux in recumbent asymptomatic human subjects.
It is concluded that in asymptomatic recumbent subjects GER is related to transient inappropriate LES relaxations rather than to low steady-state basal LES pressure and also, that primary perstalsis is the major mechanism that clears the esophagus of refluxed material. Expand
The usefulness of a structured questionnaire in the assessment of symptomatic gastroesophageal reflux disease.
The present questionnaire using descriptive language usefully identified heartburn in patients presenting with upper abdominal symptoms, and this symptom predicted symptom resolution during treatment with omeprazole. Expand
The endoscopic assessment of esophagitis: a progress report on observer agreement.
Endoscopists can identify mucosal breaks confined to a mucosal fold and lesions that extend throughout the esophageal circumference and Complications of reflux disease can be reproducibly recorded. Expand
Development of the GerdQ, a tool for the diagnosis and management of gastro‐oesophageal reflux disease in primary care
This study presents a novel and scalable approach that allows for rapid and efficient diagnosis and management of gastro‐oesophageal reflux disease in patients with symptomatic reflux. Expand
A critical review of the diagnosis and management of Barrett's esophagus: the AGA Chicago Workshop.
Based on this review of BE, the opinions of workshop members on issues pertaining to screening and surveillance are at variance with published clinical guidelines. Expand