apoptotic signaling pathway

Known as: apoptotic signalling pathway, induction of apoptosis by extracellular signals 
A series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Prostate cancer has its highest incidence in the USA and is becoming a major concern in Asian countries. Bufadienolides are… (More)
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Highly Cited
2006
Highly Cited
2006
Monoamine oxidase A (MAO A) degrades serotonin, norepinephrine, and dopamine and produces reactive oxygen that may cause neuronal… (More)
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Highly Cited
2002
Highly Cited
2002
Thalidomide (Thal) achieves responses even in the setting of refractory multiple myeloma (MM). Although increased angiogenesis in… (More)
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Highly Cited
2002
Highly Cited
2002
Targeted gene disruption studies have established that the c-Jun NH(2)-terminal kinase (JNK) signaling pathway is required for… (More)
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Review
2002
Review
2002
Apoptotic cell death is an active process mediated by various signaling pathways, which include the caspase cascade and the… (More)
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Highly Cited
2001
Highly Cited
2001
Activation of terminal caspases such as caspase-3 plays an important role in the execution of neuronal cell death after transient… (More)
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Highly Cited
2001
Highly Cited
2001
Yersinia enterocolitica induces apoptosis in macrophages by injecting the plasmid-encoded YopP (YopJ in other Yersinia species… (More)
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Highly Cited
2001
Highly Cited
2001
Apoptosis after the loss of cell anchorage--"anoikis"--plays an important role in the life cycle of adherent cells. Furthermore… (More)
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Highly Cited
1999
Highly Cited
1999
Apoptotic changes of the nucleus induced by Fas (Apo1/CD95) stimulation are completely blocked by reducing intracellular ATP… (More)
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Highly Cited
1994
Highly Cited
1994
Intracellular pathways leading from membrane receptor engagement to apoptotic cell death are still poorly characterized. We… (More)
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