apoptosome assembly

Known as: apoptosome formation 
The aggregation, arrangement and bonding together of the apoptosome, a multisubunit protein complex involved in the signaling phase of the apoptotic… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Several studies have shown that gallic acid (GA) induces apoptosis in different cancer cell lines, whereas the mechanism of… (More)
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2009
2009
Intracellular reactive oxygen species (ROS) are known to regulate apoptosis. Activation of caspase-9, the initial caspase in the… (More)
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Highly Cited
2006
Highly Cited
2006
Multiple myeloma represents an incurable disease, for which development of new therapies is required. Here, we report the effect… (More)
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Highly Cited
2006
Highly Cited
2006
Cytochrome c (CC)-initiated Apaf-1 apoptosome formation represents a key initiating event in apoptosis. This process can be… (More)
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Highly Cited
2006
Highly Cited
2006
We propose a mathematical model for mitochondria-dependent apoptosis, in which kinetic cooperativity in formation of the… (More)
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Review
2005
Review
2005
Induction of heat shock proteins (Hsps) following cellular damage can prevent apoptosis induced by both the intrinsic and the… (More)
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Review
2004
Review
2004
A plethora of apoptotic stimuli converge on the mitochondria and affect their membrane integrity. As a consequence, multiple… (More)
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Highly Cited
2004
Highly Cited
2004
Although a recent study (Zhang et al. Cell Death Differ 2002; 9; 790-800) presented that acetylcholinesterase (AChE) might be an… (More)
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2003
2003
Cytochrome c released from mitochondria into the cytoplasm plays a critical role in many forms of apoptosis by stimulating… (More)
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Highly Cited
2000
Highly Cited
2000
Release of cytochrome c from mitochondria by apoptotic signals induces ATP/dATP-dependent formation of the oligomeric Apaf-1… (More)
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