mitochondrial outer membrane permeabilization

Known as: MOMP 
The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space… (More)
National Institutes of Health

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Broader (1)

apoptotic signaling pathway

Papers overview

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Review
2010
Review
2010
Mitochondria and cell death: outer membrane permeabilization and beyond
Mitochondrial outer membrane permeabilization (MOMP) is often required for activation of the caspase proteases that cause… (More)
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Review
2009
Review
2009
PUMA cooperates with direct activator proteins to promote mitochondrial outer membrane permeabilization and apoptosis.
The BCL-2 family of proteins regulates apoptosis by controlling mitochondrial outer membrane permeabilization (MOMP). Within the… (More)
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Highly Cited
2009
Highly Cited
2009
Dynamics of outer mitochondrial membrane permeabilization during apoptosis
Individual cells within a population undergo apoptosis at distinct, apparently random time points. By analyzing cellular mitotic… (More)
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Review
2008
Review
2008
How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?
The mitochondrial pathway of apoptosis proceeds when molecules sequestered between the outer and inner mitochondrial membranes… (More)
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Review
2008
Review
2008
Lysosomal membrane permeabilization in cell death
Mitochondrial outer membrane permeabilization (MOMP) constitutes one of the major checkpoint(s) of apoptotic and necrotic cell… (More)
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2008
2008
Assessing mitochondrial outer membrane permeabilization during apoptosis.
Mitochondria play a pivotal role in the regulation of apoptosis. An imbalance in apoptosis can lead to disease. Unscheduled… (More)
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Highly Cited
2007
Highly Cited
2007
ADP/ATP carrier is required for mitochondrial outer membrane permeabilization and cytochrome c release in yeast apoptosis.
Adenine nucleotide translocator (ANT) is a mitochondrial inner membrane protein involved in the ADP/ATP exchange and is a… (More)
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Review
2007
Review
2007
Mechanisms of mitochondrial outer membrane permeabilization.
In response to many apoptotic stimuli, Bcl-2 family pro-apoptotic members, such as Bax and Bak, are activated. This results in… (More)
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Review
2006
Review
2006
Mitochondrial outer membrane permeabilization during apoptosis: the innocent bystander scenario
Mitochondrial outer membrane permeabilization (MOMP) is considered the ‘point of no return’ as this event is responsible for… (More)
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Review
2004
Review
2004
The pathophysiology of mitochondrial cell death.
In the mitochondrial pathway of apoptosis, caspase activation is closely linked to mitochondrial outer membrane permeabilization… (More)
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