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antibiotic biosynthetic process
Known as:
antibiotic formation
, antibiotic biosynthesis
, antibiotic synthesis
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The chemical reactions and pathways resulting in the formation of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and…
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National Institutes of Health
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Papers overview
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Highly Cited
2005
Highly Cited
2005
Biochemical Activities of the absA Two-Component System of Streptomyces coelicolor
Nancy L Sheeler
,
S. MacMillan
,
J. Nodwell
Journal of Bacteriology
2005
Corpus ID: 20355466
ABSTRACT The AbsA1 sensor kinase and its cognate response regulator AbsA2 are important regulators of antibiotic synthesis in…
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2004
2004
Widespread activation of antibiotic biosynthesis by S-adenosylmethionine in streptomycetes.
J. Huh
,
Dong-jin Kim
,
+8 authors
J. Suh
FEMS Microbiology Letters
2004
Corpus ID: 25923693
The effect of S-adenosylmethionine (SAM) on the production of various antibiotics was investigated to determine whether SAM…
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2004
2004
Partial activation of a silent angucycline-type gene cluster from a rubromycin beta producing Streptomyces sp. PGA64.
M. Metsä‐Ketelä
,
K. Ylihonko
,
P. Mäntsälä
Journal of antibiotics (Tokyo. )
2004
Corpus ID: 6513557
In the course of DNA-fingerprinting our strain collection for antibiotic biosynthesis genes, two different type II polyketide…
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2004
2004
Characterization of tylM3/tylM2 and mydC/mycB pairs required for efficient glycosyltransfer in macrolide antibiotic biosynthesis.
C. Melançon
,
Haruko Takahashi
,
Hung‐wen Liu
Journal of the American Chemical Society
2004
Corpus ID: 37907374
The heterologous expression of tylM3 and mydC, two homologous genes of previously unknown function, along with genes encoding…
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Highly Cited
2001
Highly Cited
2001
Genetic and transcriptional analysis of absA, an antibiotic gene cluster‐linked two‐component system that regulates multiple antibiotics in Streptomyces coelicolor
T. Anderson
,
P. Brian
,
W. Champness
Molecular Microbiology
2001
Corpus ID: 7384605
In Streptomyces coelicolor, the AbsA1–AbsA2 two‐component system regulates the expression of multiple antibiotic gene clusters…
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Highly Cited
2000
Highly Cited
2000
Mutations in Multidrug Efflux Homologs, Sugar Isomerases, and Antimicrobial Biosynthesis Genes Differentially Elevate Activity of the ςX and ςW Factors inBacillus subtilis
M. Turner
,
J. Helmann
Journal of Bacteriology
2000
Corpus ID: 21318087
ABSTRACT The ςX and ςW extracytoplasmic function sigma factors regulate more than 40 genes in Bacillus subtilis. ςW activates…
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Highly Cited
1998
Highly Cited
1998
Transcriptional Regulation of Streptomyces coelicolorPathway-Specific Antibiotic Regulators by the absA andabsB Loci
D. Aceti
,
W. Champness
Journal of Bacteriology
1998
Corpus ID: 22211683
ABSTRACT The four antibiotics produced by Streptomyces coelicolor are all affected by mutations in the absAand absB loci. The…
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Review
1990
Review
1990
Phosphate control sequences involved in transcriptional regulation of antibiotic biosynthesis.
P. Liras
,
J. Asturias
,
J. Martín
Trends in Biotechnology
1990
Corpus ID: 36024472
1978
1978
ATP and adenylate energy charge during phosphate-mediated control of antibiotic synthesis.
J. Martín
,
P. Liras
,
A. Demain
Biochemical and Biophysical Research…
1978
Corpus ID: 33381547
Review
1978
Review
1978
Mutants blocked in antibiotic synthesis.
Queener Sw
,
Sebek Ok
,
C. Vēzina
Annual Review of Microbiology
1978
Corpus ID: 19939955
INTRODUCTION ... . ........ 594 MUTANTS BLOCKED IN PRIMARY AND SECONDARY METABOLISM: A GENERAL COMPARISON OF AUXOTROPHS AND…
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