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antibiotic biosynthetic process

Known as: antibiotic formation, antibiotic biosynthesis, antibiotic synthesis 
The chemical reactions and pathways resulting in the formation of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and… 
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
Biochemical Activities of the absA Two-Component System of Streptomyces coelicolor
ABSTRACT The AbsA1 sensor kinase and its cognate response regulator AbsA2 are important regulators of antibiotic synthesis in… 
2004
2004
Widespread activation of antibiotic biosynthesis by S-adenosylmethionine in streptomycetes.
The effect of S-adenosylmethionine (SAM) on the production of various antibiotics was investigated to determine whether SAM… 
2004
2004
Partial activation of a silent angucycline-type gene cluster from a rubromycin beta producing Streptomyces sp. PGA64.
In the course of DNA-fingerprinting our strain collection for antibiotic biosynthesis genes, two different type II polyketide… 
2004
2004
Characterization of tylM3/tylM2 and mydC/mycB pairs required for efficient glycosyltransfer in macrolide antibiotic biosynthesis.
The heterologous expression of tylM3 and mydC, two homologous genes of previously unknown function, along with genes encoding… 
Highly Cited
2001
Highly Cited
2001
Genetic and transcriptional analysis of absA, an antibiotic gene cluster‐linked two‐component system that regulates multiple antibiotics in Streptomyces coelicolor
In Streptomyces coelicolor, the AbsA1–AbsA2 two‐component system regulates the expression of multiple antibiotic gene clusters… 
Highly Cited
2000
Highly Cited
2000
Mutations in Multidrug Efflux Homologs, Sugar Isomerases, and Antimicrobial Biosynthesis Genes Differentially Elevate Activity of the ςX and ςW Factors inBacillus subtilis
ABSTRACT The ςX and ςW extracytoplasmic function sigma factors regulate more than 40 genes in Bacillus subtilis. ςW activates… 
Highly Cited
1998
Highly Cited
1998
Transcriptional Regulation of Streptomyces coelicolorPathway-Specific Antibiotic Regulators by the absA andabsB Loci
ABSTRACT The four antibiotics produced by Streptomyces coelicolor are all affected by mutations in the absAand absB loci. The… 
Review
1990
Review
1990
Phosphate control sequences involved in transcriptional regulation of antibiotic biosynthesis.
1978
1978
ATP and adenylate energy charge during phosphate-mediated control of antibiotic synthesis.
Review
1978
Review
1978
Mutants blocked in antibiotic synthesis.
INTRODUCTION ... . ........ 594 MUTANTS BLOCKED IN PRIMARY AND SECONDARY METABOLISM: A GENERAL COMPARISON OF AUXOTROPHS AND… 
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