Skip to search formSkip to main contentSkip to account menu

anti-B4 blocked ricin immunoconjugate

Known as: anti-B4 blocked ricin, monoclonal antibody, Anti B4-BR, Anti-B4-bR 
An immunotoxin comprised of an anti-B4 (anti-CD19) murine monoclonal antibody linked to the modified plant-derived toxin blocked ricin. The antibody… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2000
Highly Cited
2000
This study used an 8-day continuous infusion regimen of a 1:1 mixture of two immunotoxins (ITs) prepared from deglycosylated… 
Highly Cited
1998
Highly Cited
1998
Immunotoxins, composed of a monoclonal antibody conjugated to a protein toxin, mediate cell death through novel cytotoxic… 
Highly Cited
1997
Highly Cited
1997
Anti-CD7-dgA, DA7, consists of deglycosylated ricin A chain coupled to a mouse monoclonal anti-human CD7 antibody. This study… 
Highly Cited
1993
Highly Cited
1993
PURPOSE This phase I trial was undertaken to determine the maximum-tolerated dose (MTD) and dose-limiting toxicities (DLTs) of… 
Highly Cited
1993
Highly Cited
1993
Anti-B-blocked ricin (anti-B4-bR) combines the specificity of the anti-B4 (CD19) monoclonal antibody with the protein toxin… 
Highly Cited
1993
Highly Cited
1993
Sodium chloride ingestion is stimulated during conditions of sodium deficiency to maintain body fluid and electrolyte balance… 
Highly Cited
1992
Highly Cited
1992
Anti-B4-blocked Ricin (Anti-B4-bR) is an immunotoxin comprised of the anti-B4 monoclonal antibody (MoAb) and the protein toxin… 
Highly Cited
1992
Highly Cited
1992
The antitumor activities of immunotoxins (ITs) constructed with deglycosylated ricin A chain (dgA) and either anti-CD19 (HD37) or… 
Highly Cited
1988
Highly Cited
1988
A monoclonal anti-Thy-1.1 antibody (OX7) was coupled to either native or chemically deglycosylated ricin A-chain (dgA) using one… 
Highly Cited
1988
Highly Cited
1988
The toxic lectin, ricin D, contains mannose, fucose, xylose, and N-acetylglucosamine as sugar components. Sugar chains are linked…