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anti-B4 blocked ricin immunoconjugate

Known as: anti-B4 blocked ricin, monoclonal antibody, Anti B4-BR, Anti-B4-bR 
An immunotoxin comprised of an anti-B4 (anti-CD19) murine monoclonal antibody linked to the modified plant-derived toxin blocked ricin. The antibody… 
National Institutes of Health

Papers overview

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2002
2002
PURPOSE In an effort to develop a non-lethal model of ricin toxicosis, we studied the biochemical effects of the administration… 
Highly Cited
1998
Highly Cited
1998
Immunotoxins, composed of a monoclonal antibody conjugated to a protein toxin, mediate cell death through novel cytotoxic… 
Highly Cited
1995
Highly Cited
1995
In a phase I trial, eight patients with non-Hodgkin's B-cell lym-phoma received mouse IgG1k monoclonal antibody HD37 specific for… 
1993
1993
Anti-CD19 monoclonal antibody anti-B4 (IgG1) conjugated to the novel toxin-blocked ricin forms a potent immunotoxin, anti-B4… 
1993
1993
Ricin, a toxic lectin from castor beans greatly enhances IgE responses to bee venom phospholipase A2 (PLA2) in high and low IgE… 
Highly Cited
1991
Highly Cited
1991
Twenty‐three monoclonal antibodies (MAbs) against the IL‐2 receptor α‐chain (CD25) were evaluated as ricin A‐chain immunotoxins… 
1989
1989
The mAb anti-CD5 was linked to purified ricin A chain (RTA) or intact ricin (Rc) containing B chain to determine the role of… 
Highly Cited
1984
Highly Cited
1984
A method is described for preparing specific cytotoxic agents by linking intact ricin to antibodies in a manner that produces…