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Immunoconjugates

Known as: Icon, Immunoconjugate, Immunoconjugates [Chemical/Ingredient] 
Combinations of diagnostic or therapeutic substances linked with specific immune substances such as IMMUNOGLOBULINS; MONOCLONAL ANTIBODIES; or… 
National Institutes of Health

Related topics

Related topics

40 relations

Narrower (30)

AGS67EAMG 595ANG4043D2C7-(scdsFv)-PE38KDEL

Broader (2)

AntibodiesImmunologic Factors
BRENTUXIMABBispecific CD19-directed CD3-directed T Cell Engager [EPC]ImmunotherapyImmunotoxicity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Synthesis and evaluation of novel bifunctional chelating agents based on 1,4,7,10-tetraazacyclododecane-N,N',N",N"'-tetraacetic acid for radiolabeling proteins.
Highly Cited
2003
Highly Cited
2003
Experimental comparison of three monoclonal antibodies for the class-selective immunoextraction of triazines. Correlation with molecular modeling and principal component analysis studies.
2003
2003
Icon® rice seed treatment toxicity to crayfish (Procambarus clarkii) in experimental rice paddies
Outdoor pools (2.3 × 2.3 m) were used to simulate typical rice agricultural practices in Louisiana, USA, to evaluate the toxicity… 
Highly Cited
1999
Highly Cited
1999
Monoclonal antibody conjugates of doxorubicin prepared with branched linkers: A novel method for increasing the potency of doxorubicin immunoconjugates.
Immunoconjugates of monoclonal antibody BR96 and Doxorubicin have been prepared using a novel series of branched hydrazone… 
Highly Cited
1997
Highly Cited
1997
Overcoming the nephrotoxicity of radiometal‐labeled immunoconjugates
Elevated renal uptake and extended retention of radiolabeled antibody fragments and peptides is a problem in the therapeutic… 
Highly Cited
1994
Highly Cited
1994
Effect of seven new vasoactive immunoconjugates on the enhancement of monoclonal antibody uptake in tumors
Background. To enhance monoclonal antibody uptake in tumors, seven novel vasoactive immunoconjugates were developed that… 
Highly Cited
1993
Highly Cited
1993
Potent anti-CD5 ricin A chain immunoconjugates from bacterially produced Fab' and F(ab')2.
We have used genetic engineering to obtain secretion of anti-human CD5 antibody fragments from Escherichia coli for conjugation… 
Highly Cited
1991
Highly Cited
1991
Anthracycline immunoconjugates prepared by a site-specific linkage via an amino-dextran intermediate carrier.
Anthracycline, either daunomycin or doxorubicin, was site specifically attached to the carbohydrate moiety of a monoclonal… 
Highly Cited
1991
Highly Cited
1991
Expression of genetically engineered immunoconjugates of lymphotoxin and a chimeric anti-ganglioside GD2 antibody.
Human lymphotoxin was genetically conjugated to the constant region of a human gamma 1 immunoglobulin gene at the end of either… 
Highly Cited
1988
Highly Cited
1988
Superiority of an acid-labile daunorubicin-monoclonal antibody immunoconjugate compared to free drug.
We conjugated the chemotherapy agent daunorubicin to the anti-T-cell monoclonal antibody T101 using an active ester intermediate… 
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