Immunoconjugates

Known as: Icon, Immunoconjugate, Immunoconjugates [Chemical/Ingredient] 
Combinations of diagnostic or therapeutic substances linked with specific immune substances such as IMMUNOGLOBULINS; MONOCLONAL ANTIBODIES; or… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Acute lymphoblastic leukemia (ALL) is the second most common acute leukemia in adults, with an incidence of over 6500 cases per… (More)
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Highly Cited
2008
Highly Cited
2008
The linker component of antibody-drug conjugates (ADC) is a key feature in developing optimized therapeutic agents that are… (More)
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Review
2005
Review
2005
Immunoconjugates—monoclonal antibodies (mAbs) coupled to highly toxic agents, including radioisotopes and toxic drugs… (More)
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Highly Cited
2005
Highly Cited
2005
Immunoconjugates are being explored as novel cancer therapies with the promise of target-specific drug delivery. The… (More)
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Highly Cited
2004
Highly Cited
2004
Antibody-targeted chemotherapy with gemtuzumab ozogamicin (CMA-676, a CD33-targeted immunoconjugate of N-acetyl-gamma… (More)
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Highly Cited
2002
Highly Cited
2002
The anticancer drug doxorubicin (DOX) has been linked to chimeric BR96, an internalizing monoclonal antibody that binds to a… (More)
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Highly Cited
2001
Highly Cited
2001
Antibody-targeted chemotherapy is a promising therapy in patients with acute myeloid leukemia (AML). In a phase II study of… (More)
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Highly Cited
1999
Highly Cited
1999
Leukemic blast cells express the CD33 antigen in most patients with acute myeloid leukemia (AML), but this antigen is not… (More)
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Highly Cited
1993
Highly Cited
1993
Immunoconjugates (BR96-DOX) were prepared between chimeric monoclonal antibody BR96 and the anticancer drug doxorubicin. The… (More)
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Highly Cited
1992
Highly Cited
1992
The potential of immunoconjugates of cytotoxic drugs for the treatment of cancer has not yet been realized owing to the… (More)
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