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AGS67E
Known as:
Anti-CD37 MMAE ADC AGS67E
, Anti-CD37 MMAE Antibody-drug Conjugate AGS67E
An antibody-drug conjugate (ADC) composed of AGS67C, a human anti-CD37 monoclonal antibody covalently linked, via reduced cysteines and a protease…
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National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Immunoconjugates
Monoclonal Antibodies
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Abstract 2709: Evaluation of CD37 expression and binding of AGS67E, an antibody-drug conjugate (ADC) against CD37, on white blood cells (WBCs) collected from phase I non-Hodgkin lymphoma (NHL…
S. Karki
,
H. Aviña
,
+12 authors
F. Doñate
2017
Corpus ID: 80118611
AGS67E is an antibody drug conjugate (ADC) against CD37 conjugated to monomethyl auristatin E (MMAE). CD37 is expressed on normal…
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2016
2016
A first in human experience of the anti-CD37 antibody-drug conjugate AGS67E in lymphoid malignancies.
A. Sawas
,
K. Savage
,
+9 authors
O. O’Connor
2016
Corpus ID: 79556534
7549Background: CD37 is a tetraspanin expressed in most B- and T- cell malignancies in previous tumor profiling studies (Pereira…
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2015
2015
A Phase 1 Study of the Anti-CD37 Antibody-Drug Conjugate AGS67E in Advanced Lymphoid Malignancies. Interim Results
A. Sawas
,
K. Savage
,
+8 authors
O. O’Connor
2015
Corpus ID: 208326372
Introduction. AGS67E, a fully human IgG2 antibody conjugated to the anti-tubulin agent MMAE through a cleavable linker, targets…
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2014
2014
Abstract 2650: Ags67e, an anti-cd37 monomethyl auristatin e antibody (mmae) drug conjugate as a potential therapeutic for non-hodgkin's lymphoma, chronic lymphocytic leukemia and acute myeloid…
D. Pereira
,
Claudia I. Guevara
,
+27 authors
D. Stover
2014
Corpus ID: 70779741
We have developed AGS67E, an antibody drug conjugate that targets CD37, a tetraspanin highly expressed on malignant B cells, for…
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