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The ability to sequence genomes has far outstripped approaches for deciphering the information they encode. Here we present a… Expand Techniques for systematically monitoring protein translation have lagged far behind methods for measuring messenger RNA (mRNA… Expand The crystal structure of the bacterial 70S ribosome refined to 2.8 angstrom resolution reveals atomic details of its interactions… Expand Evaluation of the electrostatic properties of biomolecules has become a standard practice in molecular biophysics. Foremost among… Expand We describe the crystal structure of the complete Thermus thermophilus 70S ribosome containing bound messenger RNA and transfer… Expand Using the atomic structures of the large ribosomal subunit from Haloarcula marismortui and its complexes with two substrate… Expand Eukaryotic translation initiation factor 4F (eIF4F) is a protein complex that mediates recruitment of ribosomes to mRNA. This… Expand By analyzing the effects of single base substitutions around the ATG initiator codon in a cloned preproinsulin gene, I have… Expand The sequence of the 3′-terminus of 16S RNA from different bacteria has been determined. Complementarity relationships between… Expand With a stepwise degradation and terminal labeling procedure the 3'-terminal sequence of E. coli 16S ribosomal RNA is shown to be… Expand