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- Publications
- Influence
Widespread A-to-I RNA Editing of Alu-Containing mRNAs in the Human Transcriptome
- A. Athanasiadis, A. Rich, S. Maas
- Biology, Medicine
- PLoS biology
- 9 November 2004
RNA editing by adenosine deamination generates RNA and protein diversity through the posttranscriptional modification of single nucleotides in RNA sequences. Few mammalian A-to-I edited genes have… Expand
Spontaneous assembly of a self-complementary oligopeptide to form a stable macroscopic membrane.
- S. Zhang, T. Holmes, C. Lockshin, A. Rich
- Chemistry, Medicine
- Proceedings of the National Academy of Sciences…
- 15 April 1993
A 16-residue peptide [(Ala-Glu-Ala-Glu-Ala-Lys-Ala-Lys)2] has a characteristic beta-sheet circular dichroism spectrum in water. Upon the addition of salt, the peptide spontaneously assembles to form… Expand
Molecular structure of a left-handed double helical DNA fragment at atomic resolution
- A. H. Wang, G. Quigley, +4 authors A. Rich
- Chemistry, Medicine
- Nature
- 13 December 1979
The DNA fragment d(CpGpCpGpCpG) crystallises as a left-handed double helical molecule with Watson–Crick base pairs and an antiparallel organisation of the sugar phosphate chains. The helix has two… Expand
Sequence-specific recognition of double helical nucleic acids by proteins.
- N. Seeman, J. Rosenberg, A. Rich
- Chemistry, Medicine
- Proceedings of the National Academy of Sciences…
- 1 March 1976
The base pairs in double helical nucleic acids have been compared to see how they can be recognized by proteins. We conclude that a single hydrogen bond is inadequate for uniquely identifying any… Expand
Extensive neurite outgrowth and active synapse formation on self-assembling peptide scaffolds.
- T. C. Holmes, S. de Lacalle, X. Su, G. Liu, A. Rich, S. Zhang
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 6 June 2000
A new type of self-assembling peptide (sapeptide) scaffolds that serve as substrates for neurite outgrowth and synapse formation is described. These peptide-based scaffolds are amenable to molecular… Expand
The molecular structure of collagen.
This paper describes in detail our work on the structure of collagen which we have already outlined elsewhere ( Rich & Crick, 1955 ). The main substance of the paper is: (1) a demonstration that,… Expand
Structural comparison of anticancer drug-DNA complexes: adriamycin and daunomycin.
- C. A. Frederick, L. Williams, +4 authors A. Wang
- Chemistry, Medicine
- Biochemistry
- 13 March 1990
The anticancer drugs adriamycin and daunomycin have each been crystallized with the DNA sequence d(CGATCG) and the three-dimensional structures of the complexes solved at 1.7- and 1.5-A resolution,… Expand
Structural domains of transfer RNA molecules.
- G. Quigley, A. Rich
- Chemistry, Medicine
- Science
- 19 November 1976
In this article, we have described various detailed features of the conformation of yeast tRNA(Phe) revealed by recent refinement analysis of x-ray diffraction data at 2.5 A resolution. The gross… Expand
Self-complementary oligopeptide matrices support mammalian cell attachment.
- S. Zhang, T. C. Holmes, C. DiPersio, R. Hynes, X. Su, A. Rich
- Materials Science, Medicine
- Biomaterials
- 1 December 1995
A new class of ionic self-complementary oligopeptides is described, two members of which have been designated RAD16 and EAK16. These oligopeptides consist of regular repeats of alternating ionic… Expand
A Z-DNA binding domain present in the human editing enzyme, double-stranded RNA adenosine deaminase.
- A. Herbert, J. Alfken, Y. Kim, I. Mian, K. Nishikura, A. Rich
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 5 August 1997
Editing of RNA changes the read-out of information from DNA by altering the nucleotide sequence of a transcript. One type of RNA editing found in all metazoans uses double-stranded RNA (dsRNA) as a… Expand