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Widespread A-to-I RNA Editing of Alu-Containing mRNAs in the Human Transcriptome
RNA editing by adenosine deamination generates RNA and protein diversity through the posttranscriptional modification of single nucleotides in RNA sequences. Few mammalian A-to-I edited genes haveExpand
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Spontaneous assembly of a self-complementary oligopeptide to form a stable macroscopic membrane.
A 16-residue peptide [(Ala-Glu-Ala-Glu-Ala-Lys-Ala-Lys)2] has a characteristic beta-sheet circular dichroism spectrum in water. Upon the addition of salt, the peptide spontaneously assembles to formExpand
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Molecular structure of a left-handed double helical DNA fragment at atomic resolution
The DNA fragment d(CpGpCpGpCpG) crystallises as a left-handed double helical molecule with Watson–Crick base pairs and an antiparallel organisation of the sugar phosphate chains. The helix has twoExpand
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Sequence-specific recognition of double helical nucleic acids by proteins.
The base pairs in double helical nucleic acids have been compared to see how they can be recognized by proteins. We conclude that a single hydrogen bond is inadequate for uniquely identifying anyExpand
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Extensive neurite outgrowth and active synapse formation on self-assembling peptide scaffolds.
A new type of self-assembling peptide (sapeptide) scaffolds that serve as substrates for neurite outgrowth and synapse formation is described. These peptide-based scaffolds are amenable to molecularExpand
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The molecular structure of collagen.
  • A. Rich, F. Crick
  • Chemistry, Medicine
  • Journal of molecular biology
  • 1 October 1961
This paper describes in detail our work on the structure of collagen which we have already outlined elsewhere ( Rich & Crick, 1955 ). The main substance of the paper is: (1) a demonstration that,Expand
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Structural comparison of anticancer drug-DNA complexes: adriamycin and daunomycin.
The anticancer drugs adriamycin and daunomycin have each been crystallized with the DNA sequence d(CGATCG) and the three-dimensional structures of the complexes solved at 1.7- and 1.5-A resolution,Expand
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Structural domains of transfer RNA molecules.
In this article, we have described various detailed features of the conformation of yeast tRNA(Phe) revealed by recent refinement analysis of x-ray diffraction data at 2.5 A resolution. The grossExpand
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Self-complementary oligopeptide matrices support mammalian cell attachment.
A new class of ionic self-complementary oligopeptides is described, two members of which have been designated RAD16 and EAK16. These oligopeptides consist of regular repeats of alternating ionicExpand
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A Z-DNA binding domain present in the human editing enzyme, double-stranded RNA adenosine deaminase.
Editing of RNA changes the read-out of information from DNA by altering the nucleotide sequence of a transcript. One type of RNA editing found in all metazoans uses double-stranded RNA (dsRNA) as aExpand
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