Ricin

Known as: Ricinus Lectin, Castor Bean Lectin, Ricins 
A phytotoxin and lectin comprised of a homodimer of ricin toxin A and B chains derived from the seeds of Ricinus communis, the castor oil plant, with… (More)
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
Bacterial Shiga-like toxins are virulence factors that constitute a significant public health threat worldwide, and the plant… (More)
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Review
2002
Review
2002
Ricin, cholera, and Shiga toxin belong to a family of protein toxins that enter the cytosol to exert their action. Since all… (More)
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Highly Cited
1999
Highly Cited
1999
The importance of cholesterol for endocytosis has been investigated in HEp-2 and other cell lines by using methyl-beta… (More)
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Highly Cited
1999
Highly Cited
1999
Ricin acts by translocating to the cytosol the enzymatically active toxin A-chain, which inactivates ribosomes. Retrograde… (More)
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Highly Cited
1997
Highly Cited
1997
Translocation of ricin A chain to the cytosol has been proposed to take place from the endoplasmic reticulum (ER), but attempts… (More)
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Review
1994
Review
1994
Ricin is an abundant protein component of Ricinus communis seeds (castor beans) that is exquisitely toxic to mammalian cells. It… (More)
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Highly Cited
1988
Highly Cited
1988
Ricin A-chain cleaves the N-glycosidic bond at A-4324 in 28 S rRNA when intact rat ribosomes are the substrate. Cleavage occurs… (More)
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Highly Cited
1987
Highly Cited
1987
Ricin is a potent cytotoxic protein derived from the higher plant Ricinus communis that inactivates eukaryotic ribosomes. In this… (More)
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Highly Cited
1987
Highly Cited
1987
The modification reaction of 28 S rRNA in eukaryotic ribosomes by ricin A-chain was characterized. To examine whether ricin A… (More)
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Highly Cited
1986
Highly Cited
1986
Receptor-mediated endocytosis and intracellular routing of native ricin, and of ricin conjugated to colloidal gold (Ri-Au) and to… (More)
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