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Ricin

Known as: Ricinus Lectin, Castor Bean Lectin, Ricins 
A phytotoxin and lectin comprised of a homodimer of ricin toxin A and B chains derived from the seeds of Ricinus communis, the castor oil plant, with… 
National Institutes of Health

Related topics

Related topics

26 relations

Narrower (9)

CNL protein, Clitocybe nebularisRicin A ChainXomaZymeZENECA ZD0490
Castor bean poisoningIn BloodProcess of secretionRicin:PrThr:Pt:XXX:Ord

Broader (3)

Chemical Warfare AgentsPlant alkaloidplant poison

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1998
1998
Selective killing of CD8+ cells with a `memory' phenotype (CD62Llo) by the N-acetyl-D-galactosamine-specific lectin from Viscum album L
As reported previously by our group, among the toxic proteins from Viscum album L. only the mistletoe lectins (MLs) induce the… 
1987
1987
Amantadine potentiates T lymphocyte killing by an anti-pan-T cell (CD5) ricin A-chain immunotoxin.
The studies described in this report demonstrate that 1-adamantanamine hydrochloride (amantadine) is a potent enhancer of the… 
Highly Cited
1986
Highly Cited
1986
Synergy between immunotoxins prepared with native ricin A chains and chemically-modified ricin B chains.
Ricin B chains treated with chloramine-T in the presence or absence of NaI show a 100-fold to 200-fold reduction in their ability… 
1984
1984
Specific killing of lymphocytes that cause experimental autoimmune myasthenia gravis by ricin toxin-acetylcholine receptor conjugates.
Experimental autoimmune myasthenia gravis (EAMG) is an autoimmune disease in which antibodies to acetylcholine receptor (AChR… 
1982
1982
Selective cytotoxicity of a ricin A-chain-anti-carcinoembryonic antigen antibody conjugate for a human colon adenocarcinoma cell line.
Ricin A-chain, the toxic subunit of the potent plant toxin ricin, has been isolated by affinity chromatography and conjugated via… 
1981
1981
Cell-specific cytotoxicity expressed by a conjugate of ricin and murine monoclonal antibody directed against thy 1.1 antigen.
The isolation and characterization are described of a conjugate between ricin, and a thy 1.1-specific monoclonal IgG2a murine… 
Highly Cited
1979
Highly Cited
1979
A hybrid protein containing the toxic subunit of ricin and the cell-specific subunit of human chorionic gonadotropin. II. Biologic properties.
The biologic properties of a purified hybrid protein containing the toxic subunit A of ricin and the cell-specific subunit of… 
1979
1979
Changes in the sensitivity of chick fibroblasts to Ricinus lectin (RCA I) toxicity in relation to the stage of embryo development.
The toxic effect of Ricinus lectin RCA I, as estimated by the inhibition of [3H]leucine incorporation, was investigated on chick… 
1979
1979
Restricted replication of two alphaviruses in ricin-resistant mouse L cells with altered glycosyltransferase activities
Two mouse L cell variant lines (CL 3 and CL 6) selected for resistance to the toxic plant lectin ricin were restricted in their… 
1972
1972
Polyribosome disaggregation in rat liver following administration of the phytotoxic proteins, abrin and ricin.
Summary As the possible mechanisms of inhibition of protein biosynthesis, it was demonstrated that the toxic proteins abrin and…