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Ricin

Known as: Ricinus Lectin, Castor Bean Lectin, Ricins 
A phytotoxin and lectin comprised of a homodimer of ricin toxin A and B chains derived from the seeds of Ricinus communis, the castor oil plant, with… 
National Institutes of Health

Related topics

Related topics

26 relations

Narrower (9)

CNL protein, Clitocybe nebularisRicin A ChainXomaZymeZENECA ZD0490
Castor bean poisoningIn BloodProcess of secretionRicin:PrThr:Pt:XXX:Ord

Broader (3)

Chemical Warfare AgentsPlant alkaloidplant poison

Papers overview

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1987
1987
Amantadine potentiates T lymphocyte killing by an anti-pan-T cell (CD5) ricin A-chain immunotoxin.
The studies described in this report demonstrate that 1-adamantanamine hydrochloride (amantadine) is a potent enhancer of the… 
1987
1987
Cloning and expression of recombinant, functional ricin B chain.
The cDNA encoding the B chain of the plant toxin ricin has been cloned and expressed in monkey kidney COS-M6 cells. The… 
Highly Cited
1986
Highly Cited
1986
Synergy between immunotoxins prepared with native ricin A chains and chemically-modified ricin B chains.
Ricin B chains treated with chloramine-T in the presence or absence of NaI show a 100-fold to 200-fold reduction in their ability… 
1985
1985
Radiation inactivation of ricin occurs with transfer of destructive energy across a disulfide bridge.
The ionizing radiation sensitivity of ricin, a disulfide-linked heterodimeric protein, was studied as a model to determine the… 
1984
1984
Specific killing of lymphocytes that cause experimental autoimmune myasthenia gravis by ricin toxin-acetylcholine receptor conjugates.
Experimental autoimmune myasthenia gravis (EAMG) is an autoimmune disease in which antibodies to acetylcholine receptor (AChR… 
1981
1981
Cell-specific cytotoxicity expressed by a conjugate of ricin and murine monoclonal antibody directed against thy 1.1 antigen.
The isolation and characterization are described of a conjugate between ricin, and a thy 1.1-specific monoclonal IgG2a murine… 
Highly Cited
1979
Highly Cited
1979
A hybrid protein containing the toxic subunit of ricin and the cell-specific subunit of human chorionic gonadotropin. II. Biologic properties.
The biologic properties of a purified hybrid protein containing the toxic subunit A of ricin and the cell-specific subunit of… 
1979
1979
Changes in the sensitivity of chick fibroblasts to Ricinus lectin (RCA I) toxicity in relation to the stage of embryo development.
The toxic effect of Ricinus lectin RCA I, as estimated by the inhibition of [3H]leucine incorporation, was investigated on chick… 
1976
1976
Site of action of ricin on the ribosome.
The extent of the inhibitory effect of ricin in polyphenylalanine synthesis by eukaryotic ribosomes is strongly dependent upon… 
1972
1972
Polyribosome disaggregation in rat liver following administration of the phytotoxic proteins, abrin and ricin.
Summary As the possible mechanisms of inhibition of protein biosynthesis, it was demonstrated that the toxic proteins abrin and…